Metrikler
Yayın
91
Açık Erişim
18
BM Sürdürülebilir Kalkınma Amaçları
Eğitim Bilgileri
2006 - 2012
2006 - 2012Doktora
Hacettepe Üniversitesi, Sağlık Bilimleri Enstitüsü, Farmasötik Kimya A.B.D., Türkiye
2004 - 2006
2004 - 2006Yüksek Lisans
Hacettepe Üniversitesi, Sağlık Bilimleri Enstitüsü, Farmasötik Kimya A.B.D., Türkiye
2000 - 2004
2000 - 2004Lisans
Hacettepe Üniversitesi, Eczacılık Fakültesi, Türkiye
Yaptığı Tezler
2012
2012Doktora
Kalsiyum modülatör etkili tiyenopiridin ve siklopentapiridin türevleri
Hacettepe Üniversitesi, Sağlık Bilimleri Enstitüsü, Farmasötik Kimya (Dr)
2006
2006Yüksek Lisans
7-sübstitüe hekzahidrokinolin türevleri ve kalsiyum kanalları üzerine etkileri
Hacettepe Üniversitesi, Eczacılık Fakültesi, Eczacılık Meslek Bilimleri Bölümü
Yabancı Diller
C1 İleri
C1 İleriİngilizce
Araştırma Alanları
Sağlık Bilimleri
Eczacılık
Meslek Bilimleri
Farmasötik Kimya
Akademik Faaliyetlere Dayalı Araştırma Alanları
Avesis Araştırma Alanları
WoS Araştırma Alanları
Scopus Araştırma Alanları
Akademik Ünvanlar / Görevler
2023 - Devam Ediyor
2023 - Devam EdiyorProf. Dr.
Hacettepe Üniversitesi, Eczacılık Fakültesi, Eczacılık Meslek Bilimleri Bölümü
2017 - 2023
2017 - 2023Doç. Dr.
Hacettepe Üniversitesi, Eczacılık Fakültesi, Eczacılık Meslek Bilimleri Bölümü
2015 - 2017
2015 - 2017Yrd. Doç. Dr.
Hacettepe Üniversitesi, Eczacılık Fakültesi, Eczacılık Meslek Bilimleri Bölümü
2004 - 2015
2004 - 2015Araştırma Görevlisi
Hacettepe Üniversitesi, Eczacılık Fakültesi, Eczacılık Meslek Bilimleri Bölümü
Akademi Dışı Deneyim
2015 - 2015
2015 - 2015Misafir Araştırıcı
Berlin Freie Universitat-Berlin / ALMANYA, Misafir Araştırıcı
2014 - 2014
2014 - 2014Misafir Araştırmacı
Berlin Freie Universitat-Berlin/ ALMANYA, Misafir Araştırmacı
2013 - 2013
2013 - 2013Misafir Araştırıcı
Berlin Freie Universitat-Berlin/ ALMANYA, Misafir Araştırıcı
2010 - 2010
2010 - 2010Misafir Araştırmacı
Ludwig Maximilian Universitat-Münih/ ALMANYA, Misafir Araştırmacı
Yönetilen Tezler
2024
2024Yüksek Lisans
Azol Halkası Taşıyan COX İnhibitörlerinin Sentezi ve Antimikrobiyal Aktivitelerinin Araştırılması
Gündüz M. G. (Danışman)
A.KARAGÜZEL(Öğrenci)
2022
2022Yüksek Lisans
Dihidropiridin türevlerinin sentezi ve L-/T-tipi kalsiyum kanal bloke edici aktiviteleri
Gündüz M. G. (Danışman)
D.AKMAN(Öğrenci)
2019
2019Yüksek Lisans
Kondanse 1,4-dihidropiridin türevlerinin sentezi ve L-/T-tipi kalsiyum kanalları üzerine etkileri
Gündüz M. G. (Danışman)
H.AYGÜN(Öğrenci)
Makaleler
Tümü (91)
SCI-E, SSCI, AHCI (88)
SCI-E, SSCI, AHCI, ESCI (90)
ESCI (2)
Scopus (90)
TRDizin (3)
Diğer Yayınlar (1)
2026
20261. Non-targeted metabolomic profiling of Cistus species and association with anticholinesterase efficacy for Alzheimer's disease: In vitro and in silico evaluation
KAHRAMAN Ç., Gonulalan E. M., Kocak E., Gokmen F. S., GÜNDÜZ M. G., NEMUTLU E., et al.
JOURNAL OF ETHNOPHARMACOLOGY
, cilt.355, 2026 (SCI-Expanded, Scopus)
2025
20252. From Sulfa Drugs to New Antibacterial Agents: Advances in Chemical Modification of Approved Sulfonamides.
Karagüzel A., Koçak Aslan E., Gündüz M. G.
Drug development research
, cilt.86, sa.8, 2025 (SCI-Expanded, Scopus)
2025
20253. Screening Natural Phenolic Compounds for Blood-Brain Barrier Permeability, Alongside GSK-3β, CK-1δ, and AChE Inhibition, for the Treatment of Alzheimer's Disease.
Gürbüz P., Doğan Ş. D., Gündüz M. G., Martínez-González L., Pérez C., Martinez A.
Drug development research
, cilt.86, sa.8, 2025 (SCI-Expanded, Scopus)
2025
20254. Synthesis, biological evaluation, molecular modeling, and DFT calculations of novel quinoline-conjugated sulfonyl hydrazones as potential anticancer agents.
Özcan E., Han M. İ., Baran M., Bitgen N., Çetinkaya Y., Gündüz M. G., et al.
Biochemical and biophysical research communications
, cilt.792, ss.152965, 2025 (SCI-Expanded, Scopus)
2025
20255. Synthesis and Isomerization of Tetrahydro-4H-chromene Derivatives
Burk R. J., Ghorai A., Mao J. X., Phan V. Q. H., Dias H. V. R., GÜNDÜZ M. G., et al.
JOURNAL OF ORGANIC CHEMISTRY
, 2025 (SCI-Expanded, Scopus)
2025
20256. Isoniazid-Derived Hydrazones Featuring Piperazine/Piperidine Rings: Design, Synthesis, and Investigation of Antitubercular Activity
Ozcan E., Vagolu S. K., Tamhaev R., Lherbet C., Mourey L., Tonjum T., et al.
BIOMOLECULES
, cilt.15, sa.9, 2025 (SCI-Expanded, Scopus)
2025
20257. Fabrication of poly(malachite green)/Nafion@nanotubes modified sensor for sensitive analysis of gallic acid and computational-electrochemical approaches on its interaction with human serum albumin
Bahend K., Bakirhan N. K., El Fazdoune M., Gündüz M. G., Bazzaoui E. A., Bazzaoui M.
MICROCHEMICAL JOURNAL
, cilt.215, ss.114277, 2025 (SCI-Expanded, Scopus)
2025
20258. Hydrazone-bridged 5-nitrofuran and piperidine/piperazine derivatives: Synthesis, DFT studies, and evaluation of anticancer and antimicrobial activity
Şimşek T., Özcan E., Çetinkaya Y., Aleksic I., Skaro Bogojevic S., Nikodinovic-Runic J., et al.
JOURNAL OF MOLECULAR STRUCTURE
, cilt.1334, ss.141863, 2025 (SCI-Expanded, Scopus)
2025
20259. Cytotoxicity-guided isolation of acacetin derivatives from Cirsium rhizocephalum CAMey. (Asteraceae) and their in silico investigation for androgen receptor inhibition against prostate cancer
Aygun A., Kilinc F., Ozmen A. S., Bayram M. E., Kiper A. N., UZUN K., et al.
CHEMICAL PAPERS
, 2025 (SCI-Expanded, Scopus)
2025
202510. Chiral Chromatographic Separation of Fifteen New Hexahydroquinoline Derivatives
Sajeevan J S., Salehi R., Burk R., Berthod A., Koçak Aslan E., Karagüzel A., et al.
CHIRALITY
, sa.5, 2025 (SCI-Expanded, Scopus)
2025
202511. Synthesis, molecular modeling, DFT studies, and enantioseparation of tetrahydro-4H-chromene derivatives with calcium channel blocking activity
Koçak Aslan E., Karagüzel A., Lam K., Dengiz C., Huang S., Burk R. J., et al.
JOURNAL OF MOLECULAR STRUCTURE
, 2025 (SCI-Expanded, Scopus)
2025
202512. Biginelli dihydropyrimidines and their acetylated derivatives as L‐/T‐type calcium channel blockers: Synthesis, enantioseparation, and molecular modeling studies
Gündüz M. G., Dengiz C., Denzinger K., Huang S., Lee J. T., Nafie J. W., et al.
ARCHIV DER PHARMAZIE
, cilt.358, sa.3, 2025 (SCI-Expanded, Scopus)
2024
202413. Tail-approach based design, synthesis, and molecular modeling of benzenesulfonamides carrying thiadiazole and urea moieties as novel carbonic anhydrase inhibitors.
Han M. İ., Gündüz M. G., Ammara A., Supuran C. T., Doğan Ş. D.
Archiv der Pharmazie
, cilt.357, 2024 (SCI-Expanded, Scopus)
2024
202414. Expanding cyclodextrin use in normal phase and super/subcritical fluid chromatographic modes for the chiral separation of 1,4-dihydropyridines
Burk R. J., Sajeevan J S. J., Salehi R., Koçak Aslan E., Gündüz M. G., Armstrong D. W.
JOURNAL OF CHROMATOGRAPHY A
, 2024 (SCI-Expanded, Scopus)
2024
202415. Experimental and computational perspectives on the interaction of nerve agent VX metabolite ethyl methylphosphonic acid with human serum albumin
Bakirhan N. K., Brahmi M., Gündüz M. G., Irem Kaya S., Sezigen S., Ozkan S. A.
MICROCHEMICAL JOURNAL
, cilt.205, 2024 (SCI-Expanded, Scopus)
2024
202416. Chiral superficially porous stationary phases for enantiomeric separation of condensed 1,4-dihydropyridine derivatives.
Salehi R., J S. J. S., Burk R. J., Berthod A., Gündüz M. G., Armstrong D. W.
Journal of pharmaceutical and biomedical analysis
, cilt.251, ss.116420, 2024 (SCI-Expanded, Scopus)
2024
202417. Synthesis, molecular modeling, DFT studies, and EPR analysis of 1,4-dihydropyridines as potential calcium channel blockers
KOÇAK ASLAN E., Lam K., DENGİZ Ç., Denzinger K., Dicle Erdamar I. Y., Huang S., et al.
Journal of Molecular Structure
, cilt.1307, 2024 (SCI-Expanded, Scopus)
2024
202418. Azole rings linked to COX inhibitors via hydrazone bridge: Synthesis, stereochemical analysis, and investigation of antimicrobial activity
Karagüzel A., Buran Uğur S., ÇETİNKAYA Y., DOĞAN Ş. D., Stevanovic M., Nikodinovic-Runic J., et al.
Journal of Molecular Structure
, cilt.1306, 2024 (SCI-Expanded, Scopus)
2024
202419. Biginelli dihydropyrimidines carrying azole rings: Synthesis, computational studies, and evaluation of alpha-glucosidase inhibitory and antimicrobial activities
KOÇAK ASLAN E., Armaković S. J., Armaković S., ÖZENVER N., ÖZKUL KOÇAK C., GÜNDÜZ M. G.
Journal of Molecular Structure
, cilt.1306, 2024 (SCI-Expanded, Scopus)
2024
202420. Electrochemical and Theoretical Investigations on the Binding of Anticancer Drug Olaparib to Human Serum Albumin
Keciba A., Bakırhan N. K., Gündüz M. G., Doulache M., Saidat B., Atici E. B., et al.
JOURNAL OF THE ELECTROCHEMICAL SOCIETY
, cilt.171, sa.6, ss.66507, 2024 (SCI-Expanded, Scopus)
2024
202421. Multivariate Approaches in Quantitative Structure–Property Relationships Study for the Photostability Assessment of 1,4-Dihydropyridine Derivatives
Chieffallo M., De Luca M., Grande F., Occhiuzzi M. A., GÜNDÜZ M. G., Garofalo A., et al.
Pharmaceutics
, cilt.16, sa.2, 2024 (SCI-Expanded, Scopus)
2023
202322. Linking quinoline ring to 5-nitrofuran moiety via sulfonyl hydrazone bridge: Synthesis, structural characterization, DFT studies, and evaluation of antibacterial and antifungal activity
DOĞAN Ş. D., Özcan E., ÇETİNKAYA Y., HAN M. İ., Şahin O., Bogojevic S. S., et al.
Journal of Molecular Structure
, cilt.1292, 2023 (SCI-Expanded, Scopus)
2023
202323. Novel Quinoline-Based Thiosemicarbazide Derivatives: Synthesis, DFT Calculations, and Investigation of Antitubercular, Antibacterial, and Antifungal Activities.
Özcan E., Vagolu S. K., Gündüz M. G., Stevanovic M., Kökbudak Z., Tønjum T., et al.
ACS omega
, cilt.8, sa.43, ss.40140-40152, 2023 (SCI-Expanded, Scopus)
2023
202324. Preparation of nanosuspensions of a 1,4-dihydropyridine-based mixed L-/T-type calcium channel blocker by combined precipitation and ultrasonication methods
PEZİK E., GÜLSÜN İNAL T., GÜNDÜZ M. G., ŞAHİN S., ÖZTÜRK N., VURAL İ.
Journal of Drug Delivery Science and Technology
, cilt.87, 2023 (SCI-Expanded, Scopus)
2023
202325. Synthesis and Evaluation of Novel Metacetamol Derivatives with Hydrazone Moiety as Anticancer and Antimicrobial Agents
Şenkardeş S., Atlıhan İ., Çayır E., Mega Tiber P., Orun O., Nigiz Ş., et al.
Chemistry and Biodiversity
, cilt.20, sa.8, 2023 (SCI-Expanded, Scopus)
2023
202326. Semicarbazides Carrying Indole Core: Synthesis, Cytotoxicity Evaluation against Human Breast Cancer Cell Lines, and Molecular Modeling Studies
Çelik B., Buran Uğur S., BARAN M., GÜNDÜZ M. G., Keskin S., ÖNDER G. Ö., et al.
Chemistry and Biodiversity
, cilt.20, sa.8, 2023 (SCI-Expanded, Scopus)
2023
202327. Investigation of Antimicrobial, Anti-Quorum Sensing, and Cytotoxic Activities of Flavonoids Isolated from Pulicaria armena Boiss. & Kotschy ex Boiss. (Asteraceae)
Başpınar Y., GÜRBÜZ P., Dilem Doğan Ş., Gözde Gündüz M. G., Aleksic I., Vojnovic S., et al.
Chemistry and Biodiversity
, cilt.20, sa.4, 2023 (SCI-Expanded, Scopus)
2023
202328. Sulfonamides linked to sulfonate esters via hydrazone functionality: synthesis, human carbonic anhydrase inhibitory activities, and molecular modeling studies
HAN M. İ., GÜNDÜZ M. G., Alçı G., Giovannuzzi S., YUVALI D., Supuran C. T., et al.
New Journal of Chemistry
, cilt.47, sa.9, ss.4267-4276, 2023 (SCI-Expanded, Scopus)
2023
202329. Synthesis, antimicrobial properties and in silico studies of aryloxyacetic acid derivatives with hydrazone or thiazolidine-4-one scaffold
ŞENKARDEŞ S., KART D., Bebek B., GÜNDÜZ M. G., Kucukguzel S. G.
JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS
, cilt.41, sa.15, ss.7421-7432, 2023 (SCI-Expanded, Scopus)
2022
202230. Indole-based hydrazone derivatives: Synthesis, cytotoxicity assessment, and molecular modeling studies
Keskin S., DOĞAN Ş. D., GÜNDÜZ M. G., Aleksic I., Vojnovic S., Lazic J., et al.
Journal of Molecular Structure
, cilt.1270, 2022 (SCI-Expanded, Scopus)
2022
202231. Focusing on C-4 position of Hantzsch 1,4-dihydropyridines: Molecular modifications, enantioseparation, and binding mechanism to L- and T-type calcium channels
Akman D., Denzinger K., Huang S., Lee J., Nafie J. W., Wolber G., et al.
European Journal of Medicinal Chemistry
, cilt.244, 2022 (SCI-Expanded, Scopus)
2022
202232. Isoniazid Linked to Sulfonate Esters via Hydrazone Functionality: Design, Synthesis, and Evaluation of Antitubercular Activity
KOÇAK ASLAN E., HAN M. İ., Krishna V. S., Tamhaev R., DENGİZ Ç., DOĞAN Ş. D., et al.
Pharmaceuticals
, cilt.15, sa.10, 2022 (SCI-Expanded, Scopus)
2022
202233. Urea derivatives carrying a thiophenylthiazole moiety: Design, synthesis, and evaluation of antitubercular and InhA inhibitory activities
Keleş Atıcı R., DOĞAN Ş. D., GÜNDÜZ M. G., Krishna V. S., Chebaiki M., Homberset H., et al.
Drug Development Research
, cilt.83, sa.6, ss.1292-1304, 2022 (SCI-Expanded, Scopus)
2022
202234. Synthesis, antimicrobial evaluation and molecular modeling studies of novel thiosemicarbazides/semicarbazides derived from p-aminobenzoic acid
İhsan Han M., İNCE U., GÜNDÜZ M. G., COŞKUN G. P., Birgül K., DOĞAN Ş. D., et al.
Journal of Molecular Structure
, cilt.1261, 2022 (SCI-Expanded, Scopus)
2022
202235. Theoretical and experimental investigation of 1,4-dihydropyridine-based hexahydroquinoline-3-carboxylates: Photophysics and bovine serum albumin binding studies
Camargo da Luz L., Gözde Gündüz M. G., Beal R., Modernell Zanotto G., Ramires Kuhn E., Augusto Netz P., et al.
Journal of Photochemistry and Photobiology A: Chemistry
, cilt.429, 2022 (SCI-Expanded, Scopus)
2022
202236. Linking azoles to isoniazid via hydrazone bridge: Synthesis, crystal structure determination, antitubercular evaluation and computational studies
KOÇAK ASLAN E., Krishna V. S., Armaković S. J., Armaković S., Şahin O., Tønjum T., et al.
Journal of Molecular Liquids
, cilt.354, 2022 (SCI-Expanded, Scopus)
2022
202237. 1,4-Dihydropyridine as a Promising Scaffold for Novel Antimicrobials Against Helicobacter pylori
Gonzalez A., Casado J., Gunduz M. G., Santos B., Velazquez-Campoy A., Sarasa-Buisan C., et al.
FRONTIERS IN MICROBIOLOGY
, cilt.13, 2022 (SCI-Expanded, Scopus)
2022
202238. Isolation, Characterization and in Silico Studies of Secondary Metabolites from Jurinea macrocephala DC. with Antiproliferative Activity
GÜRBÜZ P., DOĞAN Ş. D., GÜNDÜZ M. G., UZUN K., UZUNHİSARCIKLI E., AYCAN M. B.
CHEMISTRY & BIODIVERSITY
, cilt.19, sa.4, 2022 (SCI-Expanded, Scopus)
2022
202239. Synthesis, Antimicrobial Evaluation, and Molecular Modeling Studies of New Thiosemicarbazide-Triazole Hybrid Derivatives of (S)-Naproxen
HAN M. İ., İNCE U., GÜNDÜZ M. G., Küçükgüzel Ş. G.
Chemistry and Biodiversity
, cilt.19, 2022 (SCI-Expanded, Scopus)
2022
202240. Isoquinolinedione-urea hybrids: Synthesis, antibacterial evaluation, drug-likeness, molecular docking and DFT studies
HAN M. İ., DENGİZ Ç., Dogan S. D., GÜNDÜZ M. G., KÖPRÜ S., Ozkul C.
JOURNAL OF MOLECULAR STRUCTURE
, cilt.1252, 2022 (SCI-Expanded, Scopus)
2022
202241. Attaching azoles to Hantzsch 1,4-dihydropyridines: Synthesis, theoretical investigation of nonlinear optical properties, antimicrobial evaluation and molecular docking studies
GÜNDÜZ M. G., DENGİZ Ç., KOÇAK ASLAN E., Skaro Bogojevic S., Nikodinovic-Runic J.
JOURNAL OF MOLECULAR STRUCTURE
, cilt.1247, 2022 (SCI-Expanded, Scopus)
2021
202142. S-alkylated thiosemicarbazone derivatives: Synthesis, crystal structure determination, antimicrobial activity evaluation and molecular docking studies
GÜNDÜZ M. G., Kaya B., ÖZKUL KOÇAK C., ŞAHİN O., Rekha E. M., Sriram D., et al.
JOURNAL OF MOLECULAR STRUCTURE
, cilt.1242, 2021 (SCI-Expanded, Scopus)
2021
202143. Synthesis and Laccase-Mediated Oxidation of New Condensed 1,4-Dihydropyridine Derivatives
Milovanovic J., GÜNDÜZ M. G., Zerva A., Petkovic M., Beskoski V., Thomaidis N. S., et al.
CATALYSTS
, cilt.11, sa.6, 2021 (SCI-Expanded, Scopus)
2021
202144. Design, synthesis, antibacterial activity evaluation and molecular modeling studies of new sulfonamides containing a sulfathiazole moiety
Meseli T., DOĞAN Ş. D., GÜNDÜZ M. G., KÖKBUDAK Z., Skaro Bogojevic S., Noonan T., et al.
NEW JOURNAL OF CHEMISTRY
, cilt.45, ss.8166-8177, 2021 (SCI-Expanded, Scopus)
2021
202145. Copper-Oxone Promoted Oxidative C-H Functionalization: Synthesis of 2-Aminobenzothiazoles and Evaluation of Their Antimicrobial Activities
DOĞAN Ş. D., GÜNDÜZ M. G., Ugur S. B., Dogan H., ÖZKUL KOÇAK C., ÇETİNKAYA Y.
CHEMISTRYSELECT
, cilt.6, sa.17, ss.4382-4389, 2021 (SCI-Expanded, Scopus)
2021
202146. Crystal structure determination and computational studies of 1,4-dihydropyridine derivatives as selective T-type calcium channel blockers
GÜNDÜZ M. G., Armakovic S. J., DENGİZ Ç., Tahir M. N., Armakovic S.
JOURNAL OF MOLECULAR STRUCTURE
, cilt.1230, 2021 (SCI-Expanded, Scopus)
2021
202147. Use of Pluronic Surfactants in Gel Formulations of Photosensitive 1,4-Dihydropyridine Derivatives: A Potential Approach in the Treatment of Neuropathic Pain
Ioele G., Muzzalupo R., GÜNDÜZ M. G., De Luca M., Mazzotta E., Grande F., et al.
PHARMACEUTICS
, cilt.13, sa.4, 2021 (SCI-Expanded, Scopus)
2021
202148. In vitro biological activity of Salvia fruticosa Mill. infusion against amyloid beta-peptide-induced toxicity and inhibition of GSK-3 beta, CK-1 delta, and BACE-1 enzymes relevant to Alzheimer's disease
GÜRBÜZ P., Dokumaci A. H., GÜNDÜZ M. G., Perez C., GÖGER F., Paksoy M. Y., et al.
SAUDI PHARMACEUTICAL JOURNAL
, cilt.29, sa.3, ss.236-243, 2021 (SCI-Expanded, Scopus)
2020
202049. M3, a 1,4-Dihydropyridine Derivative and Mixed L-/T-Type Calcium Channel Blocker, Attenuates Isoproterenol-Induced Toxicity in Male Wistar Rats
Kale O. E., GÜNDÜZ M. G., Ogunbiyi B. T., Ogundare T. F., Ekor M., Awodele O.
CARDIOVASCULAR TOXICOLOGY
, cilt.20, sa.6, ss.627-640, 2020 (SCI-Expanded, Scopus)
2020
202050. 1,3-Disubstituted urea derivatives: Synthesis, antimicrobial activity evaluation and in silico studies
GÜNDÜZ M. G., Uğur S. B., Güney F., Özkul C., Krishna V. S., Kaya S., et al.
BIOORGANIC CHEMISTRY
, cilt.102, 2020 (SCI-Expanded, Scopus)
2020
202051. Design and synthesis of thiourea-based derivatives as Mycobacterium tuberculosis growth and enoyl acyl carrier protein reductase (InhA) inhibitors
DOĞAN Ş. D., GÜNDÜZ M. G., Dogan H., Krishna V. S., Lherbet C., Sriram D.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
, cilt.199, 2020 (SCI-Expanded, Scopus)
2020
202052. Discovery of hydrazone containing thiadiazoles as Mycobacterium tuberculosis growth and enoyl acyl carrier protein reductase (InhA) inhibitors
Dogan H., DOĞAN Ş. D., GÜNDÜZ M. G., Krishna V. S., Lherbet C., Sriram D., et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
, cilt.188, 2020 (SCI-Expanded, Scopus)
2020
202053. Molecular dynamics, viscoelastic properties and physical stability studies of a new amorphous dihydropyridine derivative with T-type calcium channel blocking activity
Knapik-Kowalczuk J., GÜNDÜZ M. G., Chmiel K., Jurkiewicz K., Kurek M., Tajber L., et al.
EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES
, cilt.141, 2020 (SCI-Expanded, Scopus)
2020
202054. Electrochemical Studies of Newly Synthesized 1,4-Dihydropyridine-Based Hexahydroquinoline Derivatives
Tavakkoli Z., Goljani H., GÜNDÜZ M. G., Tahir M. N., Nematollahi D.
JOURNAL OF THE ELECTROCHEMICAL SOCIETY
, cilt.167, sa.12, 2020 (SCI-Expanded, Scopus)
2019
201955. Synthesis of Disulfide-Bridged N-Phenyl-N '-(alkyl/aryl/heteroaryl)urea Derivatives and Evaluation of Their Antimicrobial Activities
Dilem Dogan S., Buran S., Gozde Gunduz M. G., Ozkul C., Siva Krishna V., Sriram D.
CHEMISTRY & BIODIVERSITY
, 2019 (SCI-Expanded, Scopus)
2019
201956. Discovery of Michael acceptor containing 1,4-dihydropyridines as first covalent inhibitors of L-/T-type calcium channels
Cevher H. A., Schaller D., Gandini M. A., KAPLAN O., Gambeta E., Zhang F. X., et al.
BIOORGANIC CHEMISTRY
, cilt.91, 2019 (SCI-Expanded, Scopus)
2019
201957. Design, synthesis and computational analysis of novel acridine-(sulfadiazine/sulfathiazole) hybrids as antibacterial agents
GÜNDÜZ M. G., Tahir M. N., Armakovic S., Kocak C., Armakovic S. J.
JOURNAL OF MOLECULAR STRUCTURE
, cilt.1186, ss.39-49, 2019 (SCI-Expanded, Scopus)
2019
201958. Direct Enantiomeric Resolution of Seventeen Racemic 1,4-Dihydropyridine-Based Hexahydroquinoline Derivatives by HPLC
Sun J., GÜNDÜZ M. G., Zhang J., Yu J., Guo X.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
, cilt.20, sa.10, 2019 (SCI-Expanded, Scopus)
2019
201959. Bioactivity-Guided Isolation of Anti-Inflammatory Principles from Cistus parviflorus Lam.
GÜRBÜZ P., DOĞAN Ş. D., Celik G. N., Bekci H., CUMAOĞLU A., GÜNDÜZ M. G., et al.
RECORDS OF NATURAL PRODUCTS
, cilt.13, sa.3, ss.226-235, 2019 (SCI-Expanded, Scopus, TRDizin)
2019
201960. A New Generation of Dihydropyridine Calcium Channel Blockers: Photostabilization of Liquid Formulations Using Nonionic Surfactants
Ioele G., GÜNDÜZ M. G., SPATARI C., DE LUCA M., GRANDE F., RAGNO G.
PHARMACEUTICS
, cilt.11, sa.1, 2019 (SCI-Expanded, Scopus)
2018
201861. Synthesis of fused 1,4-dihydropyridines as potential calcium channel blockers
Ozer E. K., GÜNDÜZ M. G., El-Khouly A., Sara Y., ŞİMŞEK R., İSKİT A. B., et al.
TURKISH JOURNAL OF BIOCHEMISTRY-TURK BIYOKIMYA DERGISI
, cilt.43, sa.6, ss.578-586, 2018 (SCI-Expanded, Scopus, TRDizin)
2018
201862. Binding mechanism investigations guiding the synthesis of novel condensed 1,4-dihydropyridine derivatives with L-/T-type calcium channel blocking activity
SCHALLER D., GÜNDÜZ M. G., Zhang F. X., Zamponi G. W., WOLBER G.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
, cilt.155, ss.1-12, 2018 (SCI-Expanded, Scopus)
2017
201763. Synthesis, crystal structure and antimycobacterial activities of 4-indolyl-1,4-dihydropyridine derivatives possessing various ester groups
BAYDAR E., GÜNDÜZ M. G., KRİSHNA V. S., ŞİMŞEK R., SRİRAM D., Yildirim S. O., et al.
RESEARCH ON CHEMICAL INTERMEDIATES
, cilt.43, sa.12, ss.7471-7489, 2017 (SCI-Expanded, Scopus)
2017
201764. Theoretical and experimental study of the ground and excited states of 1,4-dihydropyridine based hexahydroquinoline derivatives achieved by microwave irradiation
GÜNDÜZ M. G., da Silva C. d. B., ZANOTTO G. M., TOLDO J. M., ŞİMŞEK R., Safak C., et al.
NEW JOURNAL OF CHEMISTRY
, cilt.41, sa.20, ss.11686-11694, 2017 (SCI-Expanded, Scopus)
2017
201765. Synthesis and photodegradation studies of analogues of muscle relaxant 1,4-dihydropyridine compounds
GÜNDÜZ M. G., Ragno G., ŞİMŞEK R., De Luca M., Safak C., Grande F., et al.
ACTA PHARMACEUTICA
, cilt.67, sa.3, ss.341-355, 2017 (SCI-Expanded, Scopus)
2017
201766. Free radicals properties of some gamma-irradiated organic compounds
ŞİMŞEK R., GÜNDÜZ M. G., Safak C., Kokpinar O., Aydin M.
BULGARIAN CHEMICAL COMMUNICATIONS
, cilt.49, sa.1, ss.82-86, 2017 (SCI-Expanded, Scopus)
2016
201667. Photodegradation studies of 1,4-dihydropyridine compounds by MCR analysis on UV spectral data
Ioele G., GÜNDÜZ M. G., DE LUCA M., ŞİMŞEK R., Safak C., MUZZALUPO R., et al.
FUTURE MEDICINAL CHEMISTRY
, cilt.8, sa.2, ss.107-115, 2016 (SCI-Expanded, Scopus)
2016
201668. Synthesis and Biological Evaluation of New Tricyclic Dihydropyridine Based Derivatives on Potassium Channels
GÜNDÜZ M. G., KAYA YAŞAR Y., ŞİMŞEK R., ERDEMLİ İ., ŞAFAK O. C.
Iranian Journal Of Pharmaceutical Research
, 2016 (SCI-Expanded, Scopus)
2016
201669. Synthesis, structural characterization and myorelaxant activity of 4-naphthylhexahydroquinoline derivatives containing different ester groups
GÜNDÜZ M. G., ALBAYRAK E., Isli F., Fincan G. S. O., Yildirim S., ŞİMŞEK R., et al.
JOURNAL OF THE SERBIAN CHEMICAL SOCIETY
, cilt.81, sa.7, ss.729-738, 2016 (SCI-Expanded, Scopus)
2015
201570. Analgesic effect of a broad-spectrum dihydropyridine inhibitor of voltage-gated calcium channels
Gadotti V. M., Bladen C., Zhang F. X., Chen L., GÜNDÜZ M. G., ŞİMŞEK R., et al.
PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY
, cilt.467, sa.12, ss.2485-2493, 2015 (SCI-Expanded, Scopus)
2015
201571. 1,4-Dihydropyridine derivatives with T-type calcium channel blocking activity attenuate inflammatory and neuropathic pain
Bladen C., Gadotti V. M., GÜNDÜZ M. G., Berger N. D., ŞİMŞEK R., Safak C., et al.
PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY
, cilt.467, sa.6, ss.1237-1247, 2015 (SCI-Expanded, Scopus)
2015
201572. Microwave-assisted synthesis of condensed 1,4-dihydropyridines as potential calcium channel modulators
Ozer E. K., GÜNDÜZ M. G., El-Khouly A., SARA M. Y., ŞİMŞEK R., İSKİT A. B., et al.
TURKISH JOURNAL OF CHEMISTRY
, cilt.39, sa.4, ss.886-896, 2015 (SCI-Expanded, Scopus, TRDizin)
2014
201473. Synthesis and Evaluation of 1,4-Dihydropyridine Derivatives with Calcium Channel Blocking Activity
Bladen C., GÜNDÜZ M. G., ŞİMŞEK R., Safak C., Zamponi G. W.
PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY
, cilt.466, sa.7, ss.1355-1363, 2014 (SCI-Expanded, Scopus)
2014
201474. Microwave-assisted synthesis and myorelaxant activity of 9-indolyl-1,8-acridinedione derivatives
GÜNDÜZ M. G., Isli F., El-Khouly A., Yildirim S., Fincan G. S. O., ŞİMŞEK R., et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
, cilt.75, ss.258-266, 2014 (SCI-Expanded, Scopus)
2013
201375. ESR study of some gamma irradiated amino acids and condensed 1,4-dihydropyridines
Aydin M., ŞİMŞEK R., GÜNDÜZ M. G., Safak C., Osmanoglu Y. E.
JOURNAL OF MOLECULAR STRUCTURE
, cilt.1035, ss.378-382, 2013 (SCI-Expanded, Scopus)
2013
201376. Ethyl 2,7,7-trimethyl-4-(1-methyl-1H-indol-3-yl)-5-oxo-1,4,5,6,7,8-hexahydroquinoline-3-carboxylate
Yildirim S. O., Butcher R. J., GÜNDÜZ M. G., El-Khouly A., ŞİMŞEK R., Safak C.
ACTA CRYSTALLOGRAPHICA SECTION E-CRYSTALLOGRAPHIC COMMUNICATIONS
, cilt.69, 2013 (ESCI, Scopus)
2012
201277. Ethyl 4-(5-bromo-1H-indol-3-yl)-2,6,6-trimethyl-5-oxo-1,4,5,6,7,8-hexahydroquinoline-3-carboxylate
GÜNDÜZ M. G., Butcher R. J., Yildirim S. O., El-Khouly A., Safak C., ŞİMŞEK R.
ACTA CRYSTALLOGRAPHICA SECTION E-CRYSTALLOGRAPHIC COMMUNICATIONS
, cilt.68, 2012 (ESCI, Scopus)
2012
201278. Synthesis and Myorelaxant Activity of Fused 1,4-Dihydropyridines on Isolated Rabbit Gastric Fundus
Safak C., GÜNDÜZ M. G., Ilhan S. O., ŞİMŞEK R., Isli F., Yildirim S., et al.
DRUG DEVELOPMENT RESEARCH
, cilt.73, sa.6, ss.332-342, 2012 (SCI-Expanded, Scopus)
2012
201279. Investigation of myorelaxant activity of 9-aryl-3,4,6,7-tetrahydroacridine-1,8-(2H,5H,9H,10H)-diones in isolated rabbit gastric fundus
Fincan G. S. O., GÜNDÜZ M. G., Vural I. M., ŞİMŞEK R., Sarioglu Y., Safak C.
MEDICINAL CHEMISTRY RESEARCH
, cilt.21, sa.8, ss.1817-1824, 2012 (SCI-Expanded, Scopus)
2012
201280. Synthesis of Cyclopentapyridine and Thienopyridine Derivatives as Potential Calcium Channel Modulators
GÜNDÜZ M. G., SAFAK C., Kaygisiz B., Kosar B. C., ŞİMŞEK R., Erol K., et al.
ARZNEIMITTELFORSCHUNG-DRUG RESEARCH
, cilt.62, sa.4, ss.167-175, 2012 (SCI-Expanded, Scopus)
2011
201181. Two 1,4-dihydropyridine derivatives with potential calcium-channel antagonist activity
Linden A., Safak C., ŞİMŞEK R., GÜNDÜZ M. G.
ACTA CRYSTALLOGRAPHICA SECTION C-STRUCTURAL CHEMISTRY
, cilt.67, 2011 (SCI-Expanded, Scopus)
2011
201182. Antimicrobial Screening of 2 Methyl 3 Acyl 4 Aryl 2 6 6 and or 2 7 7 Trimethyl 1 4 5 6 7 8 Hexahydroquinoline Derivatives
GÜNDÜZ M. G., EKİZOĞLU M., KART D., ŞİMŞEK R., ŞAFAK O. C.
Hacettepe University, J. Faculty of Pharmacy , cilt.31, sa.1, ss.51-58, 2011 (Hakemli Dergi)
2009
200983. 7-Substituted Hexahydroquinoline Derivatives and their Calcium Channel Modulator Effects
GÜNDÜZ M. G., Celebi S., Kaygisiz B., ŞİMŞEK R., Erol K., Safak C.
LATIN AMERICAN JOURNAL OF PHARMACY
, cilt.28, sa.6, ss.922-926, 2009 (SCI-Expanded, Scopus)
2009
200984. Substituted 9-aryl-1,8-acridinedione derivatives and their effects on potassium channels
GÜNDÜZ M. G., Dogan A. E., ŞİMŞEK R., Erol K., Safak C.
MEDICINAL CHEMISTRY RESEARCH
, cilt.18, sa.4, ss.317-325, 2009 (SCI-Expanded, Scopus)
2008
200885. Structure-activity relationships of receptor binding of 1,4-dihydropyridine derivatives
Takahashi D., Oyunzul L., Onoue S., Ito Y., Uchida S., ŞİMŞEK R., et al.
BIOLOGICAL & PHARMACEUTICAL BULLETIN
, cilt.31, sa.3, ss.473-479, 2008 (SCI-Expanded, Scopus)
2008
200886. Evaluation of myorelaxant activity of 7-substituted hexahydroquinoline derivatives in isolated rabbit gastric fundus
GÜNDÜZ M. G., Ozturk G. S., Vural I. M., ŞİMŞEK R., Sarioglu Y., Safak C.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
, cilt.43, sa.3, ss.562-568, 2008 (SCI-Expanded, Scopus)
2008
200887. Synthesis of 2-Methyl-4-aryl-4,6,7,8-tetrahydro-5(1H)-quinolone Derivatives and their Effects on Potassium Channels
Oeztuerk G. S., Vural M., Guenduez M. G., ŞİMŞEK R., Sarioglu Y., SAFAK C.
ARZNEIMITTELFORSCHUNG-DRUG RESEARCH
, cilt.58, sa.12, ss.659-665, 2008 (SCI-Expanded, Scopus)
2008
200888. Synthesis and calcium modulatory activity of 3-alkyloxycarbonyl-4-(disubstituted)aryl-5-oxo-1,4,5,6,7,8-hexahydroquinoline derivatives
ŞİMŞEK R., Ozturk G. S., Vural I. M., GÜNDÜZ M. G., Sarioglu Y., Safak C.
ARCHIV DER PHARMAZIE
, cilt.341, sa.1, ss.55-60, 2008 (SCI-Expanded, Scopus)
2006
200689. Cocrystals of diastereoisomers of 1,4-dihydropyridine derivatives
Linden A., Gunduz M. G., SIMSEK R., SAFAK C.
ACTA CRYSTALLOGRAPHICA SECTION C-CRYSTAL STRUCTURE COMMUNICATIONS
, cilt.62, 2006 (SCI-Expanded, Scopus)
2006
200690. 4-Difluoro-substituted phenyl-5-oxo-hexahydroquinoline derivatives and their effects on calcium channels
Simsek R., Gunduz M. G., Sirmagul B., Safak C., Erol K., Linden A.
ARZNEIMITTELFORSCHUNG-DRUG RESEARCH
, cilt.56, sa.7, ss.529-534, 2006 (SCI-Expanded, Scopus)
2005
200591. (+/-)-Methyl and (+/-)-ethyl 4-(2,3-difluorophenyl)-2,6,6-trimethyl-5-oxo-1,4,5,6,7,8-hexahydroquinoline-3-carboxylate
Linden A., Simsek R., Gunduz M. G., Safak C.
ACTA CRYSTALLOGRAPHICA SECTION C-CRYSTAL STRUCTURE COMMUNICATIONS
, cilt.61, 2005 (SCI-Expanded, Scopus)
Desteklenen Projeler
2020 - 2022
2020 - 2022Potansiyel L-/T-Tipi Kalsiyum Kanal Blokörü Dihidropirimidin Türevlerinin Sentezi
Yükseköğretim Kurumları Destekli Proje , BAP Diğer
GÜNDÜZ M. G. (Yürütücü), DENGİZ Ç.
2017 - 2018
2017 - 2018Antimikobakteriyel Etkili Yeni 1,4-Dihidropiridin Türevleri Üzerine Çalışmalar
Yükseköğretim Kurumları Destekli Proje , BAP Diğer
GÜNDÜZ M. G. (Yürütücü)
2017 - 2018
2017 - 2018Alkil 2,6,6(2,7,7)-trimetil-4-(bifenil)-5-okso-1,4,5,6,7,8-hekzahidrokinolin 3-karboksilat türevlerinin sentezi ve karakterizasyonu
Yükseköğretim Kurumları Destekli Proje , BAP Diğer
ŞİMŞEK R. (Yürütücü), ŞAFAK O. C., GÜNDÜZ M. G., ÇETİN G.
2016 - 2017
2016 - 2017L-Tipi Kalsiyum Kanal Blokörü Kondanse 1,4-Dihidropiridin Türevlerinin Mikrodalga Yardımıyla Sentezi
Yükseköğretim Kurumları Destekli Proje , BAP Diğer
GÜNDÜZ M. G. (Yürütücü), ÇETİN G., ŞİMŞEK R., ŞAFAK O. C.
2016 - 2016
2016 - 2016BOSS XV 15. Belçika Organik Sentez Sempozyumu
Yükseköğretim Kurumları Destekli Proje , BAP Diğer
GÜNDÜZ M. G. (Yürütücü)
2016 - 2016
2016 - 2016Kondanse 14Dihidropiridin Türevlerinin Sentezi ile Antimikrobiyal ve Antioksidan Etkileri Üzerinde Çalışmalar
Yükseköğretim Kurumları Destekli Proje , BAP Diğer
ŞAFAK O. C. (Yürütücü), ŞİMŞEK R., GÜNDÜZ M. G., EKİZOĞLU M., Baydar E.
2015 - 2016
2015 - 2016Sentetik Kimya 2015, Orta Vadede Yükselen Hedefler ve Moleküller (24-27 Ağustos 2015, Helsinki-Finlandiya)
Yükseköğretim Kurumları Destekli Proje , BAP Diğer
GÜNDÜZ M. G. (Yürütücü)