ESR study of some gamma irradiated amino acids and condensed 1,4-dihydropyridines

Aydin M., ŞİMŞEK R., GÜNDÜZ M. G., Safak C., Osmanoglu Y. E.

JOURNAL OF MOLECULAR STRUCTURE, vol.1035, pp.378-382, 2013 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 1035
  • Publication Date: 2013
  • Doi Number: 10.1016/j.molstruc.2012.11.037
  • Journal Name: JOURNAL OF MOLECULAR STRUCTURE
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.378-382
  • Keywords: ESR, Free radicals, Amino acids, 1,4-Dihydropyridines, ELECTRON-SPIN-RESONANCE, L-GLUTAMIC ACID, PARAMAGNETIC-RESONANCE, FREE-RADICALS, SINGLE-CRYSTALS, L-ALANINE, ESTER HYDROCHLORIDE, ETHYL-ESTER, EPR, SPECTRUM
  • Hacettepe University Affiliated: Yes

Abstract

L-alanine methyl ester hydrochloride, 2-aminoisobutyric acid and some condensed 1,4-dihydropyridine derivatives (Compounds R1-R4) were gamma irradiated, the induced free radicals was investigated at room temperature by electron spin resonance techniques. The observed paramagnetic species of amino acids compounds were attributed to the CH3<(C)over dot>HCOOCH3 and (CH3)(2)<(C)over dot>COOH radicals, respectively. The observed spectra of the 1,4-dihydropyridine derivatives interpreted in terms of some type of amine radical fragments. The spectra were computer simulated and the g values of the radicals and the hyperfine structure constants of the unpaired electron with nearby protons and N-14 nucleus were determined. In this study, the observed paramagnetic species were found to be stable at room temperature more than 2 months. Published by Elsevier B.V.