7-Substituted Hexahydroquinoline Derivatives and their Calcium Channel Modulator Effects


GÜNDÜZ M. G. , Celebi S., Kaygisiz B., ŞİMŞEK R. , Erol K., Safak C.

LATIN AMERICAN JOURNAL OF PHARMACY, cilt.28, ss.922-926, 2009 (SCI İndekslerine Giren Dergi) identifier identifier

  • Cilt numarası: 28 Konu: 6
  • Basım Tarihi: 2009
  • Dergi Adı: LATIN AMERICAN JOURNAL OF PHARMACY
  • Sayfa Sayıları: ss.922-926

Özet

In this study, calcium antagonistic activity of sixteen hexahydroquinoline derivatives have been elucidated in rat ileum and rat thorasic aorta. In the studies on isolated rat ileum, it has been observed that all compounds showed meaningfull activity. In rat thorasic aorta studies, compound 3a has been found more active than nicardipine.