In vitro biological activity of Salvia fruticosa Mill. infusion against amyloid beta-peptide-induced toxicity and inhibition of GSK-3 beta, CK-1 delta, and BACE-1 enzymes relevant to Alzheimer's disease

GÜRBÜZ, PERİHAN; Dokumaci, Alim; GÜNDÜZ, MİYASE; Perez, Concepcion; GÖGER, FATİH; Paksoy, Mehmet; Yerer, Mukerrem; DEMİREZER, LÜTFİYE

doi:10.1016/j.jsps.2021.01.007

In vitro biological activity of Salvia fruticosa Mill. infusion against amyloid beta-peptide-induced toxicity and inhibition of GSK-3 beta, CK-1 delta, and BACE-1 enzymes relevant to Alzheimer's disease

Atıf İçin Kopyala

GÜRBÜZ P., Dokumaci A. H., GÜNDÜZ M. G., Perez C., GÖGER F., Paksoy M. Y., ...Daha Fazla

SAUDI PHARMACEUTICAL JOURNAL, cilt.29, sa.3, ss.236-243, 2021 (SCI-Expanded)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 29 Sayı: 3
Basım Tarihi: 2021
Doi Numarası: 10.1016/j.jsps.2021.01.007
Dergi Adı: SAUDI PHARMACEUTICAL JOURNAL
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, EMBASE, International Pharmaceutical Abstracts, Directory of Open Access Journals
Sayfa Sayıları: ss.236-243
Anahtar Kelimeler: Lamiaceae, Neurotoxicity, Molecular modeling, Neuroprotection, Rosmarinic acid, PHENOLIC-COMPOUNDS, FIBRIL FORMATION, DOUBLE-BLIND, ACID, ANTIOXIDANT, SAGE, EXTRACT, OFFICINALIS, PROTEIN, MEMORY
Hacettepe Üniversitesi Adresli: Evet

Özet

Salvia species have been traditionally used to improve cognition and have been proved to be a potential natural treatment for Alzheimer's disease. Salvia fruticosa Mill. (Turkish sage or Greek sage) demonstrated to have anticholinergic effects in vitro.