Metrikler
Yayın
75
Açık Erişim
4
BM Sürdürülebilir Kalkınma Amaçları
Eğitim Bilgileri
1993 - 1997
1993 - 1997Doktora
Hacettepe Üniversitesi, Eczacılık Fakültesi, Farmasötik Kimya, Türkiye
1991 - 1993
1991 - 1993Yüksek Lisans
Hacettepe Üniversitesi, Eczacılık Fakültesi, Farmasötik Kimya, Türkiye
1987 - 1991
1987 - 1991Lisans
Hacettepe Üniversitesi, Eczacılık Fakültesi, Türkiye
Yaptığı Tezler
1997
1997Doktora
Bazı biyolojik etkili kondanse heterosiklik bileşikler üzerinde çalışmalar
Hacettepe Üniversitesi, Eczacılık Fakültesi, Eczacılık Meslek Bilimleri Bölümü
1993
1993Yüksek Lisans
Biyolojik etkili kondanse tiyazolo[3,2-b]-1,2,4-triazol-5-(6H)-on türevleri üzerinde sentez çalışmaları
Hacettepe Üniversitesi, Sağlık Bilimleri Enstitüsü, Farmasötik Kimya (Yl) (Tezli)
Yabancı Diller
B2 Orta Üstü
B2 Orta Üstüİngilizce
Araştırma Alanları
Sağlık Bilimleri
Eczacılık
Meslek Bilimleri
Farmasötik Kimya
Kimya
Organik Kimya
Heterosiklik Bileşikler Kimyası
Temel Bilimler
Akademik Faaliyetlere Dayalı Araştırma Alanları
Avesis Araştırma Alanları
WoS Araştırma Alanları
Scopus Araştırma Alanları
Akademik Ünvanlar / Görevler
2010 - Devam Ediyor
2010 - Devam EdiyorProf. Dr.
Hacettepe Üniversitesi, Eczacılık Fakültesi, Eczacılık Meslek Bilimleri Bölümü
2003 - 2010
2003 - 2010Doç. Dr.
Hacettepe Üniversitesi, Eczacılık Fakültesi, Eczacılık Meslek Bilimleri Bölümü
1999 - 2003
1999 - 2003Yrd. Doç. Dr.
Hacettepe Üniversitesi, Eczacılık Fakültesi, Eczacılık Meslek Bilimleri Bölümü
1992 - 1999
1992 - 1999Araştırma Görevlisi
Hacettepe Üniversitesi, Eczacılık Fakültesi, Eczacılık Meslek Bilimleri Bölümü
Yönetimsel Görevler
2009 - Devam Ediyor
2009 - Devam EdiyorFarabi Programı Kurum Koordinatörü
Hacettepe Üniversitesi, Eczacılık Fakültesi
Akademi Dışı Deneyim
2021 - 2021
2021 - 2021Ziyaretçi Araştırmacı
Auburn Üniversitesi, Eczacılık Fakültesi Medisinal Kimya Bölümü (Alabama-ABD), Ziyaretçi Araştırmacı
2004 - 2005
2004 - 2005Misafir araştırmacı
Northeastern Üniversitesi, Farmasötik Bilimler Bölümü, Misafir araştırmacı
1996 - 1996
1996 - 1996Misafir araştırmacı
Westfäelische Wilhelms Universitesi, Farmasötik Kimya Enstitüsü, Misafir araştırmacı
Yönetilen Tezler
2015
2015Doktora
Bazı yeni kondanse triazol türevlerinin sentezi ve antikanser aktivitelerinin araştırılması
TOZKOPARAN KÖPRÜCÜ B.
S.PERİ(Öğrenci)
Makaleler
Tümü (51)
SCI-E, SSCI, AHCI (48)
SCI-E, SSCI, AHCI, ESCI (49)
ESCI (5)
Scopus (49)
TRDizin (1)
Diğer Yayınlar (1)
2025
20251. Some novel 5-benzylidenethiazolo[3,2-b]-1,2,4-triazole-6(5H)-one derivatives in the battle against cancer: Design, synthesis and their biological activities
AVCI A., Aztopal N., Gokhan-Kelekci N., ULUKAYA E., TOZKOPARAN KÖPRÜCÜ B.
JOURNAL OF MOLECULAR STRUCTURE
, cilt.1327, 2025 (SCI-Expanded, Scopus)
2024
20242. Synthesis, characterization, and MAO inhibitory activities of three new drug-like N-acylhydrazone derivatives
TAŞCİ H., HÖKELEK T., SAĞLIK ÖZKAN B. N., KAYNAK F. B., TOZKOPARAN KÖPRÜCÜ B., GÖKHAN KELEKÇİ N.
JOURNAL OF MOLECULAR STRUCTURE
, cilt.1318, 2024 (SCI-Expanded, Scopus)
2023
20233. COMPUTATIONAL IDENTIFICATION OF NOVEL TARGETS FOR DRUG CANDIDATE COMPOUNDS
SUCULARLI C., Tozkoparan B., Aytac S. P.
Journal of Research in Pharmacy
, cilt.27, ss.9-12, 2023 (ESCI, Scopus, TRDizin)
2022
20224. A new triazolothiadiazine derivative inhibits stemness and induces cell death in HCC by oxidative stress dependent JNK pathway activation
KAHRAMAN D. C., Guven E. B., Aytac P. S., Aykut G., TOZKOPARAN KÖPRÜCÜ B., Atalay R. C.
SCIENTIFIC REPORTS
, cilt.12, sa.1, 2022 (SCI-Expanded, Scopus)
2022
20225. Design, Synthesis and Biological Evaluation of Novel Triazolothiadiazoles Derived from NSAIDs as Anticancer Agents
Aytac P., Sahin I. D., ATALAY R., TOZKOPARAN KÖPRÜCÜ B.
ANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY
, cilt.22, sa.7, ss.1340-1347, 2022 (SCI-Expanded, Scopus)
2019
20196. Synthesis and structural characterization of 3-[1-[4-(2-methylpropyl)phenyl] ethyl]-6-(4-fluorophenyl)-1,2,4-triazolo[3,4-b]-1,3,4-thiadiazole
Gundogdu G., KARAYEL A., AYTAÇ S. P., TOZKOPARAN KÖPRÜCÜ B., KAYNAK F. B.
POWDER DIFFRACTION
, cilt.34, sa.4, ss.325-330, 2019 (SCI-Expanded, Scopus)
2017
20177. Structure elucidation of 3-[1-(6-methoxy-2-naphtyl)ethyl]-6-(2,4-dichlorophenyl)-7H-1,2,4-triazolo[3,4-b]-1,3,4-thiadiazine, C23H18Cl2N4OSfrom synchrotron X-ray powder diffraction
GÜNDOĞDU G., AYTAÇ S. P., MELANİE M., TOZKOPARAN B., KAYNAK F. B.
Powder Diffraction , cilt.34, ss.271-278, 2017 (SCI-Expanded, Scopus)
2017
20178. Structure determination of two structural analogs, named 3-[1-(2-fluoro-4-biphenyl)ethyl]-6-(4-fluorophenyl)-1,2,4-triazolo[3,4-b]-1,3,4-thiadiazole(C23H16F2N4S) and 3-[1-(2-fluoro-4-biphenyl)ethyl]-6-(4-chlorophenyl)-1,2,4-triazolo[3,4-b]-1,3,4-thiadiazole (C23H16ClFN4S) by synchrotron X-raypowder diffraction
GÜNDOĞDU G., AYTAÇ S. P., MELANİE M., TOZKOPARAN B., KAYNAK F. B.
Powder Diffraction , cilt.32, ss.279-289, 2017 (SCI-Expanded, Scopus)
2017
20179. Design and Synthesis of 1,2,4-Triazolo[3,2-b]-1,3,5-thiadiazine Derivatives as a Novel Template for Analgesic/Anti-Inflammatory Activity
Sert-Ozgur S., TEL B. C., Somuncuoglu E. I., KAZKAYASI İ., Ertan M., Tozkoparan B.
ARCHIV DER PHARMAZIE
, cilt.350, sa.7, 2017 (SCI-Expanded, Scopus)
2016
201610. Novel triazolothiadiazines act as potent anticancer agents in liver cancer cells through Akt and ASK-1 proteins
Aytac P. S., Durmaz I., Houston D. R., Cetin-Atalay R., TOZKOPARAN KÖPRÜCÜ B.
BIOORGANIC & MEDICINAL CHEMISTRY
, cilt.24, sa.4, ss.858-872, 2016 (SCI-Expanded, Scopus)
2016
201611. Crystal structure determination of two novel 1,2,4-triazolo[3,4-b]-1,3,4-thiadiazine and -thiadiazole derivatives by XRPD method
KAYNAK F. B., Gundogdu G., Muller M., ÖZBEY S.
ACTA CRYSTALLOGRAPHICA A-FOUNDATION AND ADVANCES
, cilt.72, 2016 (SCI-Expanded, Scopus)
2015
201512. Novel thiazolo[3,2-b]-1,2,4-triazoles derived from naproxen with analgesic/anti-inflammatory properties: Synthesis, biological evaluation and molecular modeling studies
SARIGOL D., UZGOREN-BARAN A., TEL B. C., Somuncuoglu E. İ., KAZKAYASI İ., OZADALI-SARI K., et al.
BIOORGANIC & MEDICINAL CHEMISTRY
, cilt.23, sa.10, ss.2518-2528, 2015 (SCI-Expanded, Scopus)
2012
201213. Thiazolo[3,2-b]-1,2,4-triazole-5(6H)-one substituted with ibuprofen: Novel non-steroidal anti-inflammatory agents with favorable gastrointestinal tolerance
Uzgoren-Baran A., TEL B. C., SARIGOL D., Ozturk E. I., KAZKAYASI İ., Okay G., et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
, cilt.57, ss.398-406, 2012 (SCI-Expanded, Scopus)
2012
201214. Design and synthesis of some thiazolotriazolyl esters as anti-inflammatory and analgesic agents
Tozkoparan B., AYTAÇ S. A., Gursoy S., AKTAY G.
MEDICINAL CHEMISTRY RESEARCH
, cilt.21, sa.2, ss.192-201, 2012 (SCI-Expanded, Scopus)
2012
201215. Novel 1,2,4-Triazolo[3,4-b]-1,3,4-thiadiazole Derivatives as Dual Analgesic/Anti-inflammatory and Antimicrobial Agents
Tozkoparan B., Aytac S. P., Gursoy S., GÜNAL S., AKTAY G.
LETTERS IN DRUG DESIGN & DISCOVERY
, cilt.9, sa.2, ss.204-212, 2012 (SCI-Expanded, Scopus)
2010
201016. A joint theoretical and experimental structural study of two novel 1,2,4-triazolo[3,4-b]-1,3,4-thiadiazine derivatives
Kaynak F. B., Aytac S. P., Tozkoparan B.
STRUCTURAL CHEMISTRY
, cilt.21, sa.4, ss.795-802, 2010 (SCI-Expanded, Scopus)
2009
200917. Synthesis of 3,6-disubstituted 7H-1,2,4-triazolo[3,4-b]-1,3,4-thiadiazines as novel analgesic/anti-inflammatory compounds
AYTAÇ S. A., Tozkoparan B., KAYNAK F. B., Aktay G., Goektas O., Uenuevar S.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
, cilt.44, sa.11, ss.4528-4538, 2009 (SCI-Expanded, Scopus)
2009
200918. Novel 3,6-Disubstituted 7H-1,2,4-Triazolo[3,4-b][1,3,4]thiadiazines: Synthesis, Characterization, and Evaluation of Analgesic/Anti-inflammatory, Antioxidant Activities
Tozkoparan B., Aytac S. P., Aktay G.
ARCHIV DER PHARMAZIE
, cilt.342, sa.5, ss.291-298, 2009 (SCI-Expanded, Scopus)
2009
200919. Investigation of antioxidant properties of some 6-(alpha-aminobenzyl) thiazolo[3,2-b]-1,2,4-triazole-5-ol compounds
AKTAY G., Tozkoparan B., Ertan M.
JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY
, cilt.24, sa.3, ss.898-902, 2009 (SCI-Expanded, Scopus)
2008
200820. The antioxidant properties and the COX-inhibitory effects of some 6-(a-aminobenzyl) thiazolo [3,2-b]-1,2,4-triazole-5-ol compounds
Aktay G., Tozkoparan B., Ertan M.
BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY
, cilt.102, ss.44, 2008 (SCI-Expanded, Scopus)
2007
200721. Preparation of 5-aryl-3-alkylthio-1,2,4-triazoles and corresponding sulfones with antiinflammatory-analgesic activity
Tozkoparan B., KUPELI E., YESILADA E., Ertan M.
BIOORGANIC & MEDICINAL CHEMISTRY
, cilt.15, sa.4, ss.1808-1814, 2007 (SCI-Expanded, Scopus)
2007
200722. Design and synthesis of some new thiazolo[3,2-b]-1,2,4-triazole-5(6H)-ones substituted with flurbiprofen as anti-inflammatory and analgesic agents
DOĞDAŞ E., TOZKOPARAN B., KAYNAK F. B., ERİKSSON L., KUPELI E., YEŞİLADA E., et al.
ARZNEIMITTEL-FORSCHUNG-DRUG RESEARCH
, cilt.57, sa.4, ss.196-202, 2007 (SCI-Expanded, Scopus)
2006
200623. 3-phenyl-5-(2-thienyl)-2-pyrazoline-1-thioamide
Isik S., Koysal Y., Ozdemir Z., Bilgin A.
ACTA CRYSTALLOGRAPHICA SECTION E-CRYSTALLOGRAPHIC COMMUNICATIONS
, cilt.62, 2006 (SCI-Expanded, ESCI, Scopus)
2005
200524. Two N-substituted 3,5-diphenyl-2-pyrazoline-1-thiocarboxamides
Koysal Y., Isik S., Sahin G., Palaska E.
ACTA CRYSTALLOGRAPHICA SECTION C-STRUCTURAL CHEMISTRY
, cilt.61, 2005 (SCI-Expanded, Scopus)
2005
200525. 2-[(2-Chloro-3,4-dimethoxybenzylidene)amino]-adamantane
Isik S., Koysal Y., Septioglu E., Calis U.
ACTA CRYSTALLOGRAPHICA SECTION E-CRYSTALLOGRAPHIC COMMUNICATIONS
, cilt.61, 2005 (SCI-Expanded, ESCI, Scopus)
2005
200526. 1-[(2-Chloro-3,4-dimethoxybenzylidene)amino]-adamantane
Isik S., Koysal Y., Septioglu E., Calis U.
ACTA CRYSTALLOGRAPHICA SECTION E-CRYSTALLOGRAPHIC COMMUNICATIONS
, cilt.61, 2005 (SCI-Expanded, ESCI, Scopus)
2005
200527. Protective effects of thiazolo[3,2-b]-1,2,4-triazoles on ethanol-induced oxidative stress in mouse brain and liver
AKTAY G., Tozkoparan B., ERTAN M.
ARCHIVES OF PHARMACAL RESEARCH
, cilt.28, sa.4, ss.438-442, 2005 (SCI-Expanded, Scopus)
2005
200528. Synthesis and evaluation of analgesic/anti-inflammatory and antimicrobial activities of 3-substituted-1,2,4-triazole-5-thiones
Tozkoparan B., KUPELI E., YESILADA E., ISIK S., OZALP M. A., ERTAN M.
ARZNEIMITTELFORSCHUNG-DRUG RESEARCH
, cilt.55, sa.9, ss.533-540, 2005 (SCI-Expanded, Scopus)
2005
200529. Synthesis and evaluation of analgesic/anti-inflammatory and antimicrobial activities of 3-substituted-1,2,4-triazole-5-thiones
TOZKOPARAN B., KUPELI E., YEŞİLADA E., Isik S., ÖZALP M., Ertan M.
ARZNEIMITTELFORSCHUNG-DRUG RESEARCH
, cilt.55, sa.9, ss.533-540, 2005 (SCI-Expanded, Scopus)
2005
200530. Mechanistic studies of inactivation of glutathione S transferase Pi isozyme by a haloenol lactone derivative
JİANG Z., GHANG L., TOZKOPARAN B., WEN D.
Medicinal Chemistry
, cilt.1, ss.191-198, 2005 (Scopus)
2004
200431. 5-(2-chlorobenzoyl)-1,3-benzoxazol-2(3H)-one
Isik S., Koysal Y., Yavuz M., Koksal M., Erdogan H.
ACTA CRYSTALLOGRAPHICA SECTION E-CRYSTALLOGRAPHIC COMMUNICATIONS
, cilt.60, 2004 (SCI-Expanded, ESCI, Scopus)
2004
200432. 2-[6-(3-Chlorophenyl)-2,4-dioxo-perhydropyrimidin-3-yl]ethyl morpholine-4-carbodithioate
Koysal Y., Isik S., Septioglu E., Calis U.
ACTA CRYSTALLOGRAPHICA SECTION C-STRUCTURAL CHEMISTRY
, cilt.60, 2004 (SCI-Expanded, Scopus)
2004
200433. 6-(2-Fluorobenzylidene)-2-[1-(2-fluoro-4-biphenyl)ethyl]-thiazolo[3,2-b][1,2,4]triazol-5(6H)-one
KOYSAL Y., ISIK S., DOGDAS E., Tozkoparan B., ERTAN M.
ACTA CRYSTALLOGRAPHICA SECTION C-STRUCTURAL CHEMISTRY
, cilt.60, 2004 (SCI-Expanded, Scopus)
2004
200434. 3-[4-(4-Fluorophenyl)piperazin-1-ylmethyl]-5-methyl-1,3-benzoxazol-2(3H)-one and 3-[4-(2-fluorophenyl)piperazin-1-ylmethyl]-5-methyl-1,3-benzoxazol-2 (3H)-one
Koysal Y., Isik S., Koksal M., Erdogan H., Gokhan N.
ACTA CRYSTALLOGRAPHICA SECTION C-STRUCTURAL CHEMISTRY
, cilt.60, 2004 (SCI-Expanded)
2004
200435. Effects of nonsteroidal antiinflammatory drugs on the thiol groups and lipid peroxidation in ethanol induced oxidative stress
AKTAY G., TOZKOPARAN B., Ertan M.
Acta Pharmaceutica Turcica , cilt.46, ss.107-112, 2004 (Hakemli Dergi)
2004
200436. Synthesis, characterization and anti-inflammatory-analgesic properties of 6-(α-amino-4-chlorobenzyl)thiazolo[3,2-b]-1,2,4-triazol-5-ols
Tozkoparan B., Gokhan N., KUPELI E., YESILADA E., ERTAN M.
ARZNEIMITTELFORSCHUNG-DRUG RESEARCH
, cilt.54, sa.1, ss.35-41, 2004 (SCI-Expanded)
2003
200337. 3-[4-(2-Chlorophenyl)piperazinomethyl]-5-methyl-1-benzoxazolin-2(3H)-one
Koysal Y., Isik S., Koksal M., Erdogan H., Gokhan N.
ACTA CRYSTALLOGRAPHICA SECTION E-STRUCTURE REPORTS ONLINE
, cilt.59, 2003 (SCI-Expanded)
2002
200238. Methyl 2-methyl-7-oxo-1,2,4-triazolo[3,2-b]-1,3-thiazine-5-carboxylate
OZBEY S., Tozkoparan B.
ACTA CRYSTALLOGRAPHICA SECTION E-STRUCTURE REPORTS ONLINE
, cilt.58, 2002 (SCI-Expanded)
2002
200239. Synthesis of some 1,2,4-triazolo[3,2-b]-1,3-thiazine-7-ones with potential analgesic and antiinflammatory activities
Tozkoparan B., AKTAY G., YESILADA E.
FARMACO
, cilt.57, sa.2, ss.145-152, 2002 (SCI-Expanded, Scopus)
2001
200140. Synthesis of some thiazolo[3,2-b]-1,2,4-triazole-5(6H)-ones and their novel Michael addition products with anti-inflammatory activities
Tozkoparan B., AKTAY G., YESILADA E., ERTAN M.
ARZNEIMITTEL-FORSCHUNG-DRUG RESEARCH
, cilt.51, sa.6, ss.470-477, 2001 (SCI-Expanded, Scopus)
2000
200041. Studies on synthesis, chromatographic resolution, and antiinflammatory activities of some 2-thioxo-1,2,3,4-tetrahydropyrimidines and their condensed derivatives
Tozkoparan B., YARIM M., Sarac S., ERTAN M., Kelicen P., ALTINOK G., et al.
ARCHIV DER PHARMAZIE
, cilt.333, sa.12, ss.415-420, 2000 (SCI-Expanded, Scopus)
2000
200042. 6-benzylidenethiazolo[3,2-b]-1,2,4-triazole-5(6H)-ones substituted with ibuprofen:: synthesis, characterization and evaluation of anti-inflammatory activity
Tozkoparan B., GOKHAN N., AKTAY G., YESILADA E., ERTAN M.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
, cilt.35, sa.7-8, ss.743-750, 2000 (SCI-Expanded, Scopus)
1999
199943. Synthesis and evaluation of anti-inflammatory activity of some thiazolo[3,2-b]-1,2,4-triazole-5(6H)-ones and their Michael addition products
Tozkoparan B., KILCIGIL G., ERTAN R., ERTAN M., Kelicen P., DEMIRDAMAR R.
ARZNEIMITTEL-FORSCHUNG-DRUG RESEARCH
, cilt.49, sa.12, ss.1006-1011, 1999 (SCI-Expanded, Scopus)
1999
199944. 6-Benzylidene-2-(2-chlorophenyl)thiazolo[3,2-b]-1,2,4-triazol-5(6H)-one
OZBEY S., KENDI E., Tozkoparan B., ERTAN M.
ACTA CRYSTALLOGRAPHICA SECTION C-CRYSTAL STRUCTURE COMMUNICATIONS
, cilt.55, ss.1939-1941, 1999 (SCI-Expanded, Scopus)
1999
199945. Synthesis and anti-inflammatory activities of some thiazolo[3,2-a]pyrimidine derivatives
Tozkoparan B., ERTAN M., KELICEN P., DEMIRDAMAR R.
FARMACO
, cilt.54, sa.9, ss.588-593, 1999 (SCI-Expanded, Scopus)
1998
199846. Condensed heterocyclic compounds: Synthesis and antiinflammatory activity of novel thiazolo[3,2-a]pyrimidines
Tozkoparan B., ERTAN M., KREBS B., LAGE M., Kelicen P., DEMIRDAMAR R.
ARCHIV DER PHARMAZIE
, cilt.331, sa.6, ss.201-206, 1998 (SCI-Expanded, Scopus)
1998
199847. Method validation in pharmaceutical analysis: From a general approach to capillary electrophoresis
YESILADA A., GOKHAN N., Tozkoparan B., ERTAN M., ABOUL-ENEIN H.
JOURNAL OF LIQUID CHROMATOGRAPHY & RELATED TECHNOLOGIES
, cilt.21, sa.17, ss.2619-2632, 1998 (SCI-Expanded, Scopus)
1998
199848. Development and validation of a capillary electrophoretic method for the determination of degradation product in naphazoline HCl bulk drug substance
Yesilada A., TOZKOPARAN B., GOKHAN N., ONER L., ERTAN M.
JOURNAL OF LIQUID CHROMATOGRAPHY & RELATED TECHNOLOGIES
, cilt.21, sa.17, ss.2575-2588, 1998 (SCI-Expanded, Scopus)
1997
199749. (1R,2S,4S,11S)-4-isopropyl-1-methyl-2(alpha-N-morpholino-3-methoxybenzyl)cyclohexan-3-one
ERTAN M., YESILADA A., Tozkoparan B., TARIMCI C., KREBS B., LAGE M.
ACTA CRYSTALLOGRAPHICA SECTION C-CRYSTAL STRUCTURE COMMUNICATIONS
, cilt.53, ss.1466-1468, 1997 (SCI-Expanded, Scopus)
1996
199650. Synthesis of some 2-arylpropionic acid amides as prodrugs
AKGUN H., Tozkoparan B., ERTAN M., AKSU F., INAN S.
ARZNEIMITTEL-FORSCHUNG/DRUG RESEARCH
, cilt.46, sa.9, ss.891-894, 1996 (SCI-Expanded, Scopus)
1995
199551. SYNTHESIS OF SOME THIAZOLO[3,2-B]-1,2,4-TRIAZOLE-5(6H)-ONE AS POTENTIAL PLATELET-AGGREGATION INHIBITORS
TOZKOPARAN B., AKGUN H., ERTAN M., RUBSEMANN K.
ARCHIV DER PHARMAZIE
, cilt.328, sa.2, ss.169-173, 1995 (SCI-Expanded, Scopus)
Hakemli Bilimsel Toplantılarda Yayımlanmış Bildiriler
2019
20191. A NEW THIADIAZINE DERIVATIVE INDUCES OXIDATIVE STRESS DEPENDENT CELL DEATH IN HEPATOCELLULAR CARCINOMA STEM CELLS
KAHRAMAN D. C., GÜVEN E. B., Aytac P., TOZKOPARAN KÖPRÜCÜ B., ATALAY R.
Annual Meeting of the American-Association-for-the-Study-of-Liver-Diseases (AASLD) / Liver Meeting, Massachusetts, Amerika Birleşik Devletleri, 8 - 12 Kasım 2019, cilt.70, (Özet Bildiri)
2019
20192. A new thiadiazine derivative induces oxidative stress dependent JNK pathway activation and cell death in hepatocellular carcinoma
KAHRAMAN D. C., GÜVEN E. B., TOZKOPARAN KÖPRÜCÜ B., ATALAY R.
Annual Meeting of the American-Association-for-Cancer-Research (AACR), Georgia, Amerika Birleşik Devletleri, 29 Mart - 03 Nisan 2019, cilt.79, (Özet Bildiri)
2017
20173. Computational Activity and Target Prediction for Three Novel Triazolothiadiazine Derivatives
SUCULARLI C., TOZKOPARAN B.
5th International BAU Drug Design Congress, 19 - 21 Ekim 2017, (Tam Metin Bildiri)
2017
20174. A Valid Scaffold for Monoamine Oxidases Inhibitors
Tasçı H., SAĞLIK B. N., ÖZKAY Y., TOZKOPARAN B., GÖKHAN KELEKÇİ N.
2nd International Gazi Pharma Symposium Series (GPSS-2017), 11 - 13 Ekim 2017, (Özet Bildiri)
2017
20175. A Study on Synthesis of Novel Mannich Bases Derived From 1,2,4-Triazole-5-thione Containing Naproxen Moiety
TOZKOPARAN B., Tasçı H., GÖKHAN KELEKÇİ N.
2nd International Gazi Pharma Symposium Series (GPSS-2017), 11 - 13 Ekim 2017, (Özet Bildiri)
2017
20176. Novel Mannich Bases Derived From 1,2,4-Triazole-5-thione Containing Naproxen Moiety as Analgesic/Anti-inflammatory Compounds
Tasçı H., TOZKOPARAN B., GÖKHAN KELEKÇİ N.
Multidisciplinary Symposium on Drug Research and Development 2017(DRD-2017), 5 - 07 Ekim 2017, (Özet Bildiri)
2017
20177. Synthesis and Evaluation of Novel Hydrazone Derivatives as Monoamine Oxidase Inhibitors
Tasçı H., SAĞLIK B. N., ÖZKAY Y., TOZKOPARAN B., GÖKHAN KELEKÇİ N.
Multidisciplinary Symposium on Drug Research and Development 2017(DRD-2017), 5 - 07 Ekim 2017, (Özet Bildiri)
2017
20178. New Bis Mannich Bases of 1,2,4-Triazoles with Analgesic/Antiinflammatory Activities
SERT OZGUR S., TEL B. C., KAZKAYASI İ., SOMUNCUOĞLU E. İ., Ertan M., TOZKOPARAN B.
AIMECS2017, Chemistry in Drug Discovery, Design and Development, 23 - 27 Temmuz 2017, (Özet Bildiri)
2016
20169. Protective Effects of New Selective COX 2 Inhibitors on a Rat Model of Severe Acute Pancreatitits
ERİKÇİ A., UÇAR B. İ., Salgın Gökşen U., GÖKHAN KELEKÇİ N., UZGÖREN BARAN A., TOZKOPARAN B., et al.
41.FEBS Congress, Kuşadası-Aydın, Türkiye, 3 - 08 Eylül 2016
2016
201610. Protective effects of new selective COX-2 inhibitors on a rat model of severe acute pancreatitis
Erikci A., Ucar B. I., BAYSAL İ., Goksen U. S., Kelekci N. G., Baran A., et al.
41st FEBS Congress on Molecular and Systems Biology for a Better Life, Kusadasi, Türkiye, 3 - 08 Eylül 2016, cilt.283, ss.246, (Özet Bildiri)
2015
201511. Novel 1,2,4-Triazole-based bicyclic derivates bearing naproxen moiety as analgesic/anti-inflammatory agents
UZGÖREN BARAN A., SARIGÖL D., TEL B. C., SOMUNCUOĞLU E. İ., KAZKAYASI İ., OKAY G., et al.
International Multidisciplinary Symposium on Drug Research and Development, Türkiye, 15 Ekim 2015, (Özet Bildiri)
2015
201512. Novel 1 2 4 Triazole Based Bicyclic Derivatives Bearing Naproxen Moiety As Analgesic Anti Inflammatory Agents
UZGÖREN BARAN A., TEL B. C., SOMUNCUOĞLU E. İ., KAZKAYASI İ., OKAY G., TOZKOPARAN B.
International Multidisciplinary Symposium on Drug Research and Development in Memory of Professor Ünsal Çalış, Eskişehir, Türkiye, 15 - 17 Ekim 2015
2015
201513. Novel Triazole Based Condensed Derivatives As Putative Anticancer Agents
AYTAÇ S. P., DURMAZ İ., ÇETİN ATALAY R., TOZKOPARAN B.
Pharma Middle East, Dubai, Birleşik Arap Emirlikleri, 1 - 04 Ekim 2015
2015
201514. Bologna Süreci Çalışmaları Sonrası Hacettepe Üniversitesi Eczacılık Fakültesi Lisans Programına Bakış
TEL B. C., ERDOĞAN S., SÜSLÜ İ., YABANOĞLU ÇİFTÇİ S., SÖZEN ŞAHNE B., SAYGILI N., et al.
I. Bologna Süreci Araştırmaları Kongresi, Ankara, Türkiye, 17 - 18 Eylül 2015
2015
201515. Evaluation of Graduate Students Scientific Development at theHacettepe University Graduate School of Health Sciences
ÖZTÜRK ÇOPUR E., TOZKOPARAN B., KARABULUT E., YAŞAR Ü., FADILLIOĞLU E.
10th ORPHEUS Conference Challenges in evaluation of research outcomes in PhD education, Sırbistan, Belçika, 16 - 18 Nisan 2015
2012
201216. Synthesis of some 1,2,4-triazolo[3,4-b]-1,3,4-thiadiazine derivatives as possible protein kinase inhibitors
Guven E. B., Aytac P. S., Cetin-Atalay R., Tozkoparan B.
22nd IUBMB Congress/37th FEBS Congress, Sevilla, İspanya, 4 - 09 Eylül 2012, cilt.279, ss.144-145, (Özet Bildiri)
2010
201017. Synthesis, characterization and pharmacological evaluation of some new bis mannich bases derived from 1,2,4-triazoles
Sert Ozgur S., TOZKOPARAN KÖPRÜCÜ B., Ertan M., SOMUNCUOĞLU E. İ., KAZKAYASI İ., TEL B. C.
4th International Meeting on Medicinal and Pharmaceutical Chemistry (IMMPC-4) and 6th International Symposium on Pharmaceutical Chemistry (ISPC-6), Türkiye, 30 Eylül 2010, (Özet Bildiri)
Kitaplar
2018
20181. Türk Farmakopesi
TUNÇBİLEK M., YEŞİLADA A., BALKAN A., TOZKOPARAN B., PALASKA E., ÖZKANLI F., et al.
T. C. Sağlık Bakanlığı Türkiye İlaç ve Tıbbi Cihaz Kurumu, Ankara, 2018
2016
20162. Kinolonlar
Ertan M., TOZKOPARAN B.
Farmasötik Kimya, , Editör, Hacettepe Üniversitesi Yayınları, Ankara, ss.1079-1093, 2016
Desteklenen Projeler
2022 - 2025
2022 - 2025Gastrointestinal Sistem Açısından Güvenli Yeni Bir Grup Triazol Türevi Analjezik/Antiinflamatuvar Bileşiğin Tasarımı, Sentezi, Karakterizasyonu ve COX Enzim İnhibitörü Etkilerinin Değerlendirilmesi
Yükseköğretim Kurumları Destekli Proje , BAP Diğer
TOZKOPARAN KÖPRÜCÜ B. (Yürütücü), ÖZKAY Y., PELİN SAĞLIK B. N., TAŞCİ H., GÖKHAN KELEKÇİ N., AVCI A., et al.
2022 - 2024
2022 - 2024Bazı Yeni Tiyazolo[3,2-b]-1,2,4-triazol-6(5H)-on Türevlerinin in siliko ve in vitro EGFR İnhibisyon Etkilerinin İncelenmesi
Yükseköğretim Kurumları Destekli Proje , BAP Diğer
TOZKOPARAN KÖPRÜCÜ B. (Yürütücü), GÖKHAN KELEKÇİ N., AVCI A., AZTOPAL N., ULUKAYA E.
2018 - 2021
2018 - 2021Bazı Yeni Tiyazolo(3,2-b)-1,2,4-triazol-6(5H)-on Türevlerinin Sentezi ve Sitotoksik Etkilerinin Araştırılması
Yükseköğretim Kurumları Destekli Proje , BAP Y.Lisans
TOZKOPARAN KÖPRÜCÜ B. (Yürütücü), AVCI A., AZTOPAL N.
2018 - 2019
2018 - 2019MAO İnhibitörü etki göstermesi beklenen hidrazon iskeleti taşıyan yeni bileşiklerin sentez ve yapı tayini çalışmaları
Yükseköğretim Kurumları Destekli Proje , BAP Diğer
GÖKHAN KELEKÇİ N. (Yürütücü), TAŞCİ H., TOZKOPARAN KÖPRÜCÜ B.
2018 - 2019
2018 - 2019Yeni 1-Aminometil-1,2,4-triazol-5-tiyon Bileşiklerinin Sentezi ve Yapı Aydınlatma Çalışmaları
Yükseköğretim Kurumları Destekli Proje , BAP Diğer
TOZKOPARAN KÖPRÜCÜ B. (Yürütücü), TAŞCİ H., AVCI A., GÖKHAN KELEKÇİ N.
2017 - 2017
2017 - 201718. Tetrahedron Sempozyumu, Asya Versiyonu
Yükseköğretim Kurumları Destekli Proje , BAP Diğer
TOZKOPARAN KÖPRÜCÜ B. (Yürütücü)
2015 - 2016
2015 - 2016Bazı Yeni Kondanse Triazol Türevlerinin Sentezi ve Antikanser Aktivitelerinin Araştırılması
Yükseköğretim Kurumları Destekli Proje , BAP Doktora
TOZKOPARAN KÖPRÜCÜ B. (Yürütücü), AYTAÇ S. P.
2015 - 2016
2015 - 2016OLASI ANTİKANSER BİLEŞİKLER OLARAK YENİ TRİAZOL ESASLI KONDANSE TÜREVLER
Yükseköğretim Kurumları Destekli Proje , BAP Diğer
TOZKOPARAN KÖPRÜCÜ B. (Yürütücü), ÇETİN ATALAY R., AYTAÇ S. P., DURMAZ İ.