SYNTHESIS OF SOME THIAZOLO[3,2-B]-1,2,4-TRIAZOLE-5(6H)-ONE AS POTENTIAL PLATELET-AGGREGATION INHIBITORS


TOZKOPARAN B. , AKGUN H. , ERTAN M. , RUBSEMANN K.

ARCHIV DER PHARMAZIE, cilt.328, ss.169-173, 1995 (SCI İndekslerine Giren Dergi) identifier identifier

  • Cilt numarası: 328 Konu: 2
  • Basım Tarihi: 1995
  • Doi Numarası: 10.1002/ardp.19953280215
  • Dergi Adı: ARCHIV DER PHARMAZIE
  • Sayfa Sayıları: ss.169-173

Özet

Twenty new compounds having 2-methyl-6-benzylidenethiazolo[3,2-b]-1,2,4-triazole-5(6H)-one (2a-d) and 2-methyl-6-(alpha-aminobenzyl)thiazolo[3,2-b]-1,2,4-triazole-5-ol (5-20) structures were synthesized. Their structures were confirmed by elemental and spectroscopic analysis and their platelet aggregation inhibitory activities were investigated.