SYNTHESIS OF SOME THIAZOLO[3,2-B]-1,2,4-TRIAZOLE-5(6H)-ONE AS POTENTIAL PLATELET-AGGREGATION INHIBITORS

TOZKOPARAN B., AKGUN H., ERTAN M., RUBSEMANN K.

ARCHIV DER PHARMAZIE, vol.328, no.2, pp.169-173, 1995 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 328 Issue: 2
  • Publication Date: 1995
  • Doi Number: 10.1002/ardp.19953280215
  • Journal Name: ARCHIV DER PHARMAZIE
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.169-173
  • Hacettepe University Affiliated: Yes

Abstract

Twenty new compounds having 2-methyl-6-benzylidenethiazolo[3,2-b]-1,2,4-triazole-5(6H)-one (2a-d) and 2-methyl-6-(alpha-aminobenzyl)thiazolo[3,2-b]-1,2,4-triazole-5-ol (5-20) structures were synthesized. Their structures were confirmed by elemental and spectroscopic analysis and their platelet aggregation inhibitory activities were investigated.