SYNTHESIS OF SOME THIAZOLO[3,2-B]-1,2,4-TRIAZOLE-5(6H)-ONE AS POTENTIAL PLATELET-AGGREGATION INHIBITORS

TOZKOPARAN, BİRSEN; AKGUN, HÜLYA; ERTAN, MEVLÜT; RUBSEMANN, K

doi:10.1002/ardp.19953280215

SYNTHESIS OF SOME THIAZOLO[3,2-B]-1,2,4-TRIAZOLE-5(6H)-ONE AS POTENTIAL PLATELET-AGGREGATION INHIBITORS

TOZKOPARAN B., AKGUN H., ERTAN M., RUBSEMANN K.

ARCHIV DER PHARMAZIE, cilt.328, sa.2, ss.169-173, 1995 (SCI-Expanded, Scopus)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 328 Sayı: 2
Basım Tarihi: 1995
Doi Numarası: 10.1002/ardp.19953280215
Dergi Adı: ARCHIV DER PHARMAZIE
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.169-173
Hacettepe Üniversitesi Adresli: Evet

Özet

Twenty new compounds having 2-methyl-6-benzylidenethiazolo[3,2-b]-1,2,4-triazole-5(6H)-one (2a-d) and 2-methyl-6-(alpha-aminobenzyl)thiazolo[3,2-b]-1,2,4-triazole-5-ol (5-20) structures were synthesized. Their structures were confirmed by elemental and spectroscopic analysis and their platelet aggregation inhibitory activities were investigated.