Metrikler
Yayın
100
Açık Erişim
18
BM Sürdürülebilir Kalkınma Amaçları
Duyurular & Dokümanlar
Dosya İndir
Eğitim Bilgileri
2012 - 2018
2012 - 2018Doktora
Hacettepe Üniversitesi, Sağlık Bilimleri Enstitüsü, Farmasötik Kimya A.B.D., Türkiye
2007 - 2012
2007 - 2012Yüksek Lisans
İnönü Üniversitesi, Sağlık Bilimleri Enstitüsü, Farmasötik Kimya (Yl), Türkiye
2000 - 2004
2000 - 2004Lisans
İstanbul Üniversitesi, Eczacılık Fakültesi, Türkiye
Yaptığı Tezler
2018
2018Doktora
(Arilalkil)azol yapısında yeni oksim ester türevleri üzerinde çalışmalar: Sentez, biyolojik aktivite ve moleküler modelleme
Hacettepe Üniversitesi, Sağlık Bilimleri Enstitüsü, Farmasötik Kimya A.B.D.
2012
2012Yüksek Lisans
Yeni (Arilalkil) triazol türevi oksim esterlerin sentezleri, antikonvülsan ve antimikrobiyal aktiviteleri
İnönü Üniversitesi, Acil Tıp A.B.D. (ing.), Anatomi A.B.D. (Türkçe)
Yabancı Diller
C1 İleri
C1 İleriİngilizce
Sertifika, Kurs ve Eğitimler
2014
2014Eğiticilerin Eğitimi Programı
Eğitim Yönetimi ve Planlama
Hacettepe Üniversitesi Yaşam Boyu Öğrenme Merkezi
2014
2014Deney Hayvanı Kullanım Sertifikası
Sağlık ve Tıp
Hacettepe Üniversitesi Hayvan Deneyleri Yerel Etik Kurulu
Araştırma Alanları
Sağlık Bilimleri
Eczacılık
Meslek Bilimleri
Farmasötik Kimya
Akademik Ünvanlar / Görevler
2020 - Devam Ediyor
2020 - Devam EdiyorDr. Öğr. Üyesi
Hacettepe Üniversitesi, Eczacılık Fakültesi, Eczacılık Meslek Bilimleri Bölümü
2013 - 2020
2013 - 2020Araştırma Görevlisi
Hacettepe Üniversitesi, Eczacılık Fakültesi, Eczacılık Meslek Bilimleri Bölümü
Akademi Dışı Deneyim
2016 - 2016
2016 - 2016Misafir Araştırmacı
Yeni Zelanda Auckland Üniversitesi, Misafir Araştırmacı
2015 - 2015
2015 - 2015Misafir araştırmacı
Yeni Zelanda Auckland Üniversitesi, Misafir araştırmacı
Makaleler
Tümü (78)
SCI-E, SSCI, AHCI (73)
SCI-E, SSCI, AHCI, ESCI (78)
ESCI (4)
Scopus (78)
TRDizin (3)
2026
20261. Synthesis, crystallography, biological activity, and molecular modeling studies of some 3-Aryl-2-(4-(substitutedphenyl)thiazol-2-yl) acrylonitrile derivatives
Anas S., Moncol J., NİGİZ Ş., ÖZKUL KOÇAK C., Vagolu S. K., SARI S., et al.
JOURNAL OF MOLECULAR STRUCTURE
, cilt.1350, 2026 (SCI-Expanded, Scopus)
2025
20252. Unveiling a New Cholinesterase Inhibitor Iridoid From Verbascum uschakense (Murb.) Hub.-Mor.: In Vitro and In Silico Evaluation
Mindiz R. S., TOPÇU G., ŞÖHRETOĞLU D., SARI S., ÖZBEK M. U., KAHRAMAN Ç.
CHEMICAL BIOLOGY & DRUG DESIGN
, cilt.106, sa.4, 2025 (SCI-Expanded, Scopus)
2025
20253. Histone deacetylase inhibitory properties of metabolites from leaves of Quercus pontica K. Koch and its metabolites
RENDA G., Sevgi S., Soral M., BORA AKOĞLU G., SARI S., Cetin O., et al.
INTERNATIONAL JOURNAL OF ENVIRONMENTAL HEALTH RESEARCH
, cilt.35, sa.6, ss.1616-1627, 2025 (SCI-Expanded, Scopus)
2025
20254. Ranolazine attenuates mouse detrusor contractility: Evidence for the involvement of calcium-related mechanisms
BARUT E. N., Erac Y., Daglar G., Sari S., DUMAN M.
EUROPEAN JOURNAL OF PHARMACOLOGY
, 2025 (SCI-Expanded, Scopus)
2025
20255. Novel 2-Alkoxy-3-Cyanopyridine Derivatives as Cholinesterase Inhibitors: Synthesis, Biological Evaluation, and In Silico Investigations
Kadi I., SEYHAN G., Zebbiche Z., SARI S., BARUT B., Boumoud T., et al.
CHEMISTRY & BIODIVERSITY
, 2025 (SCI-Expanded, Scopus)
2025
20256. The role of unsaturated fatty acids in modulating human butyrylcholinesterase activity: insights from kinetics and molecular docking
Gok M., Cicek C., SARI S., BODUR E.
NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY
, 2025 (SCI-Expanded, Scopus)
2025
20257. Inhibitor Action of Unsaturated Fatty Acids on Equine Serum Butyrylcholinesterase
Akay M. B., Şener K., Sarı S., Bodur E.
PROTEIN JOURNAL
, 2025 (SCI-Expanded, Scopus)
2024
20248. Potent Antimicrobial Azoles: Synthesis, In Vitro and In Silico Study
ÖZDEMİR Z., ZENNİ Y. N., Karakurt A., SARI S., Sarac S., Akdag M., et al.
ANTIBIOTICS-BASEL
, cilt.13, sa.11, 2024 (SCI-Expanded, Scopus)
2024
20249. New Ester-Containing Azole Derivatives With Potent Anti-Candida Effects: Synthesis, Antifungal Susceptibility, Cytotoxicity, and Molecular Modeling Studies
Ataker Y., Oncue O., GÜLMEZ KIVANÇ D., SABUNCUOĞLU S., ARIKAN AKDAĞLI S., SARI S.
DRUG DEVELOPMENT RESEARCH
, cilt.85, sa.7, 2024 (SCI-Expanded, Scopus)
2024
202410. Alpha-Glucosidase Inhibitory Effects of Flavonoids, Phenolic Acids and Iridoids Isolated From Vinca Soneri: In Vitro and In Silico Perspectives
Uyanir E., Soral M., SEYHAN G., AKKAYA D., BARUT B., SARI S., et al.
CHEMISTRY & BIODIVERSITY
, cilt.21, sa.10, 2024 (SCI-Expanded, Scopus)
2024
202411. Galactokinase-like protein from Leishmania donovani: Biochemical and structural characterization of a recombinant protein
Baber H., Aghajani A., Gallimore B. H., Bethel C., Hyatt J. G., King E. F., et al.
Biochimie
, cilt.223, ss.31-40, 2024 (SCI-Expanded, Scopus)
2024
202412. Effective α-glycosidase inhibitors based on polyphenolic benzothiazole heterocycles
Sevimli E., SEYHAN G., AKKAYA D., SARI S., BARUT B., Köksoy B.
Bioorganic Chemistry
, cilt.147, 2024 (SCI-Expanded, Scopus)
2024
202413. In vitro and in silico investigation of FDA-approved drugs to be repurposed against Alzheimer's disease
AKKAYA D., SEYHAN G., SARI S., BARUT B.
Drug Development Research
, cilt.85, sa.3, 2024 (SCI-Expanded, Scopus)
2024
202414. Azoles display promising anticonvulsant effects through possible PPAR-α activation
SARI S., Yurtoğlu S., ZENGİN M., Marcinkowska M., Siwek A., Saraç S.
Neuroscience Letters
, cilt.828, 2024 (SCI-Expanded, Scopus)
2024
202415. A transcriptomics-based drug repositioning approach to identify drugs with similar activities for the treatment of muscle pathologies in spinal muscular atrophy (SMA) models
Hoolachan J. M., McCallion E., Sutton E. R., Çetin Ö., Pacheco-Torres P., Dimitriadi M., et al.
Human Molecular Genetics
, cilt.33, sa.5, ss.400-425, 2024 (SCI-Expanded, Scopus)
2024
202416. Discovery of novel IDO1/TDO2 dual inhibitors: a consensus Virtual screening approach with molecular dynamics simulations, and binding free energy analysis
Hanif N., SARI S.
Journal of Biomolecular Structure and Dynamics
, 2024 (SCI-Expanded, Scopus)
2024
202417. Myrtenyl-bispidine containing azole: synthesis and antifungal activity
Li-Zhulanov N. S., Ponomarev K. Y., Sarı S., Gülmez Kıvanç D., Arıkan Akdağlı S., Krasnov V. I., et al.
Mendeleev Communications
, cilt.34, sa.1, ss.119-121, 2024 (SCI-Expanded, Scopus)
2023
202318. Advances in the natural α-glucosidase inhibitors
ŞÖHRETOĞLU D., RENDA G., Arroo R., Xiao J., SARI S.
eFood
, cilt.4, sa.5, 2023 (Scopus)
2023
202319. Virtual screening, identification and in vitro validation of small molecule GDP-mannose dehydrogenase inhibitors
Dolan J. P., Ahmadipour S., Wahart A. J. C., Cheallaigh A. N., SARI S., Eurtivong C., et al.
RSC Chemical Biology
, cilt.4, sa.11, ss.865-870, 2023 (ESCI, Scopus)
2023
202320. Synthesis and biological evaluation of novel zinc (II) and nickel (II) phthalocyanines as cholinesterase inhibitors
AKKAYA D., BARUT B., SARI S., REIS R., Fazli H., BIYIKLIOĞLU Z., et al.
Journal of Organometallic Chemistry
, cilt.995, 2023 (SCI-Expanded, Scopus)
2023
202321. Azole derivatives inhibit wildtype butyrylcholinesterase and its common mutants
SARI S., ÖNDER S., AKKAYA D., SABUNCUOĞLU S., ZENGİN M., BARUT B., et al.
Drug Development Research
, cilt.84, sa.5, ss.1018-1028, 2023 (SCI-Expanded, Scopus)
2023
202322. Design, Synthesis, and Molecular Modeling of New and Safe Azole Oxime Esters with Promising Antifungal Activity
Yurtoğlu S., SARI S., KART D., SABUNCUOĞLU S., Saraç S.
ChemistrySelect
, cilt.8, sa.18, 2023 (SCI-Expanded, Scopus)
2023
202323. Rational Design of New Monoterpene-Containing Azoles and Their Antifungal Activity
Li-Zhulanov N. S., Zaikova N. P., Sarı S., Gülmez Kıvanç D., Sabuncuoğlu S., Özadalı Sarı K., et al.
Antibiotics
, cilt.12, sa.5, 2023 (SCI-Expanded, Scopus)
2023
202324. The inhibitory effect of escitalopram on mouse detrusor contractility: The role of L-type calcium channels
ENGİN S., BARUT E. N., Erac Y., SARI S., DUMAN M.
Toxicology and Applied Pharmacology
, cilt.461, 2023 (SCI-Expanded, Scopus)
2023
202325. Novel activity of human BChE: Lipid hydrolysis
Gok M., Cicek C., Sarı S., Bodur E.
Biochimie
, cilt.204, ss.127-135, 2023 (SCI-Expanded, Scopus)
2023
202326. Molecular and Computational Analysis Identify Statins as Selective Inhibitors of Human Butyrylcholinesterase
Atay M. S., SARI S., BODUR E.
Protein Journal
, cilt.42, 2023 (SCI-Expanded, Scopus)
2022
202227. Design, Synthesis, and Biological Evaluation of Some Benzothiazolone Derivatives as Cholinesterase Inhibitors
ALAGÖZ M. A., AKKAYA D., ARSLAN G., Uludağ B., ÖZDEMİR Z., BARUT B., et al.
ChemistrySelect
, cilt.7, sa.46, 2022 (SCI-Expanded, Scopus)
2022
202228. Bioactive Saponins of Primula vulgaris Huds. Promote Wound Healing through Inhibition of Collagenase and Elastase Enzymes: in Vivo, in Vitro and in Silico Evaluations
KAHRAMAN Ç., SARI S., AKKOL E., ÇANKAYA İ. İ.
CHEMISTRY & BIODIVERSITY
, cilt.19, 2022 (SCI-Expanded, Scopus)
2022
202229. In Vitro and in Silico Investigation of DNA Interaction, Topoisomerase I and II Inhibitory Properties of Polydatin
ŞÖHRETOĞLU D., BARUT B., SARI S., ÖZEL A., Kuruuzum-Uz A., Arroo R.
CHEMISTRY & BIODIVERSITY
, cilt.19, sa.10, 2022 (SCI-Expanded, Scopus)
2022
202230. Inhibition of Cholinesterases by Benzothiazolone Derivatives
ALAGÖZ M. A., Kim S., Oh J. M., ARSLAN G., ÖZDEMİR Z., SARI S., et al.
PROCESSES
, cilt.10, sa.9, 2022 (SCI-Expanded, Scopus)
2022
202231. In Vitro Cytotoxicity of Methano[1,2,4]Triazolo-[1,5-C][1,3,5]Benzoxadiazocine Derivatives and Their Effects on Nitrite and Prostaglandin E2 (PGE2) Levels
DOĞAN İ. S., GÜMÜŞ M. K., Gorobets N. Y., Reis R., Orak D., SİPAHİ H., et al.
PHARMACEUTICAL CHEMISTRY JOURNAL
, cilt.56, sa.6, ss.769-776, 2022 (SCI-Expanded, Scopus)
2022
202232. Anti-inflammatory and Antinociceptive Potential of Verbascum latisepalum
KAHRAMAN Ç., SARI S., AKKOL E., AKDEMİR Z. Ş., ÇANKAYA İ. İ.
REVISTA BRASILEIRA DE FARMACOGNOSIA-BRAZILIAN JOURNAL OF PHARMACOGNOSY
, cilt.32, sa.4, ss.537-543, 2022 (SCI-Expanded, Scopus)
2022
202233. Antifungal Azole Derivatives Featuring Naphthalene Prove Potent and Competitive Cholinesterase Inhibitors with Potential CNS Penetration According to the in Vitro and in Silico Studies
SARI S., AKKAYA D., ZENGİN M., SABUNCUOĞLU S., ÖZDEMİR Z., ALAGÖZ M. A., et al.
CHEMISTRY & BIODIVERSITY
, cilt.19, sa.7, 2022 (SCI-Expanded, Scopus)
2022
202234. Synthesis, Molecular Modelling and In Vitro Anti-inflammatory Activity of Novel 1,2,4-Triazolo[4,3-a]quinoxaline Derivatives
DOĞAN İ. S., KAHVECİ B., SARI S., Kolci K., Reis R., SİPAHİ H.
CHEMISTRYSELECT
, cilt.7, sa.26, 2022 (SCI-Expanded, Scopus)
2022
202235. Rutin increases alpha-tubulin acetylation via histone deacetylase 6 inhibition
Cetin O., SARI S., Erdem-Yurter H., BORA G.
DRUG DEVELOPMENT RESEARCH
, cilt.83, sa.4, ss.993-1002, 2022 (SCI-Expanded, Scopus)
2022
202236. Multiple biological effects of secondary metabolites of Ziziphus jujuba: isolation and mechanistic insights through in vitro and in silico studies
ŞÖHRETOĞLU D., Bakir S. D., BARUT B., Soral M., SARI S.
EUROPEAN FOOD RESEARCH AND TECHNOLOGY
, cilt.248, ss.1059-1067, 2022 (SCI-Expanded, Scopus)
2022
202237. Potential of nafimidone derivatives against co-morbidities of epilepsy: In vitro, in vivo, and in silico investigations
SARI S., BARUT B., Marcinkowska M., SABUNCUOĞLU S., AVCI A., KOÇAK ASLAN E., et al.
DRUG DEVELOPMENT RESEARCH
, cilt.83, sa.1, ss.184-193, 2022 (SCI-Expanded, Scopus)
2022
202238. Flavonoids as tyrosinase inhibitors in in silico and in vitro models: basic framework of SAR using a statistical modelling approach
Jakimiuk K., SARI S., Milewski R., Supuran C. T., ŞÖHRETOĞLU D., Tomczyk M.
JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY
, cilt.37, sa.1, ss.421-430, 2022 (SCI-Expanded, Scopus)
2022
202239. Azoles containing naphthalene with activity against Gram-positive bacteria: in vitro studies and in silico predictions for flavohemoglobin inhibition
SARI S., SABUNCUOĞLU S., KOÇAK ASLAN E., AVCI A., KART D., ÖZDEMİR Z., et al.
JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS
, cilt.40, sa.20, ss.10220-10229, 2022 (SCI-Expanded, Scopus)
2022
202240. Inhibitory Action of Omega-3 and Omega-6 Fatty Acids Alpha-Linolenic, Arachidonic and Linoleic acid on Human Erythrocyte Acetylcholinesterase
Akay M. B., Şener K., Sarı S., Bodur E.
Protein Journal
, cilt.42, 2022 (SCI-Expanded, Scopus)
2022
202241. A hybrid ligand and structure-based virtual screening of NCI compound library identifies potential SAPT1 inhibitors
SARI S., Valand N., Girija U. V.
JOURNAL OF RESEARCH IN PHARMACY
, cilt.26, sa.3, ss.617-624, 2022 (ESCI, TRDizin)
2021
202142. In silico Repurposing of Drugs for pan-HDAC and pan-SIRT Inhibitors: Consensus Structure-based Virtual Screening and Pharmacophore Modeling Investigations
SARI S., AVCI A., Aslan E.
TURKISH JOURNAL OF PHARMACEUTICAL SCIENCES
, cilt.18, sa.6, ss.730-737, 2021 (ESCI, Scopus, TRDizin)
2021
202143. Alpha-glucosidase and tyrosinase inhibiton of polyphenols isolated from Potentilla speciosa var. speciosa: In vitro and in silico perspectives
Özgünseven A., BARUT B., Šoral M., SARI S., AKAYDIN G., ÖZEL A., et al.
Industrial Crops and Products
, cilt.170, 2021 (SCI-Expanded, Scopus)
2021
202144. Azole antifungal compounds could have dual cholinesterase inhibitory potential according to virtual screening, enzyme kinetics, and toxicity studies of an inhouse library
BARUT B., SARI S., SABUNCUOĞLU S., ÖZEL A.
Journal of Molecular Structure
, cilt.1235, 2021 (SCI-Expanded, Scopus)
2021
202145. Discovery of potent alpha-glucosidase inhibitors through structure-based virtual screening of an in-house azole collection
SARI S., Barut B., ÖZEL A., Sarac S.
CHEMICAL BIOLOGY & DRUG DESIGN
, cilt.97, sa.3, ss.701-710, 2021 (SCI-Expanded, Scopus)
2021
202146. Inhibition of cholinesterases by safranin O: Integration of inhibition kinetics with molecular docking simulations
ÖNDER S., SARI S., TACAL Ö.
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS
, cilt.698, 2021 (SCI-Expanded, Scopus)
2021
202147. Azole derivatives with naphthalene showing potent antifungal effects against planktonic and biofilm forms ofCandidaspp.: an in vitro and in silico study
SARI S., Kocak E., KART D., ÖZDEMİR Z., ACAR M., Sayoglu B., et al.
INTERNATIONAL MICROBIOLOGY
, cilt.24, sa.1, ss.93-102, 2021 (SCI-Expanded, Scopus)
2020
202048. Antibacterial azole derivatives: Antibacterial activity, cytotoxicity, and in silico mechanistic studies
SARI S., AVCI A., Kocak E., KART D., SABUNCUOĞLU S., DOĞAN İ. S., et al.
DRUG DEVELOPMENT RESEARCH
, cilt.81, sa.8, ss.1026-1036, 2020 (SCI-Expanded, Scopus)
2020
202049. In vitro and in silico assessment of DNA interaction, topoisomerase I and II inhibition properties of chrysosplenetin
Şöhretoğlu D., Barut B., Sari S., Özel A., Arroo R.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
, cilt.163, ss.1053-1059, 2020 (SCI-Expanded, Scopus)
2020
202050. Flavonoids as alpha-glucosidase inhibitors: mechanistic approaches merged with enzyme kinetics and molecular modelling
ŞÖHRETOĞLU D., SARI S.
PHYTOCHEMISTRY REVIEWS
, cilt.19, sa.5, ss.1081-1092, 2020 (SCI-Expanded, Scopus)
2020
202051. Flavones as tyrosinase inhibitors: kinetic studies in vitro and in silico
Arroo R. R. J., SARI S., Barut B., ÖZEL A., Ruparelia K. C., ŞÖHRETOĞLU D.
PHYTOCHEMICAL ANALYSIS
, cilt.31, sa.3, ss.314-321, 2020 (SCI-Expanded, Scopus)
2020
202052. Synthesis, DNA interaction, in vitro/in silico topoisomerase II inhibition and photodynamic therapy activities of two cationic BODIPY derivatives
BARUT B., ÇOBAN Ö., YALÇIN C. Ö., Baş H., SARI S., BIYIKLIOĞLU Z., et al.
Dyes and Pigments
, cilt.174, 2020 (SCI-Expanded, Scopus)
2020
202053. p-Trifluoroacetophenone Oxime Ester Derivatives: Synthesis, Antimicrobial and Cytotoxic Evaluation, and Molecular Modeling Studies
Bozbey I., Sarı S., Şalva E., Kart D., Karakurt A.
Letters In Drug Design & Discovery
, cilt.17, sa.2, ss.169-183, 2020 (SCI-Expanded, Scopus)
2019
201954. Novel water soluble BODIPY compounds: Synthesis, photochemical, DNA interaction, topoisomerases inhibition and photodynamic activity properties
BARUT B., YALÇIN C. Ö., SARI S., ÇOBAN Ö., Keleş T., BIYIKLIOĞLU Z., et al.
European Journal of Medicinal Chemistry
, cilt.183, 2019 (SCI-Expanded, Scopus)
2019
201955. A new series of pyridazinone derivatives as cholinesterases inhibitors: Synthesis, in vitro activity and molecular modeling studies
Ozcelik A. B., ÖZDEMİR Z., SARI S., Utku S., Uysal M.
PHARMACOLOGICAL REPORTS
, cilt.71, sa.6, ss.1253-1263, 2019 (SCI-Expanded, Scopus)
2019
201956. Discovery and Characterisation of Dual Inhibitors of Tryptophan 2,3-Dioxygenase (TDO2) and Indoleamine 2,3-Dioxygenase 1 (IDO1) Using Virtual Screening.
Sari S., Tomek P., Leung E., Reynisson J.
Molecules (Basel, Switzerland)
, cilt.24, 2019 (SCI-Expanded, Scopus)
2019
201957. Tyrosinase inhibitory effects of Vinca major and its secondary metabolites: Enzyme kinetics and in silico inhibition model of the metabolites validated by pharmacophore modelling
SARI S., BARUT B., ÖZEL A., ŞÖHRETOĞLU D.
BIOORGANIC CHEMISTRY
, cilt.92, 2019 (SCI-Expanded, Scopus)
2019
201958. Discovery of new azoles with potent activity against Candida spp. and Candida albicans biofilms through virtual screening
SARI S., KART D., Ozturk N., KAYNAK F. B., Gencel M., Taskor G., et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
, cilt.179, ss.634-648, 2019 (SCI-Expanded, Scopus)
2019
201959. Antifungal screening and in silico mechanistic studies of an in-house azole library
SARI S., KART D., SABUNCUOĞLU S., DOĞAN İ. S., ÖZDEMİR Z., Bozbey I., et al.
CHEMICAL BIOLOGY & DRUG DESIGN
, cilt.94, ss.1944-1955, 2019 (SCI-Expanded, Scopus)
2019
201960. Synthesis, in vivo anticonvulsant testing, and molecular modeling studies of new nafimidone derivatives
ACAR M., SARI S., DALKARA S.
DRUG DEVELOPMENT RESEARCH
, cilt.80, sa.5, ss.606-616, 2019 (SCI-Expanded, Scopus)
2019
201961. Synthesis and cytotoxicity studies on new pyrazole-containing oxime ester derivatives
KARAKURT A., Bozbey I., USLU H., SARI S., ÖZDEMİR Z., ŞALVA E.
TROPICAL JOURNAL OF PHARMACEUTICAL RESEARCH
, cilt.18, sa.6, ss.1315-1322, 2019 (SCI-Expanded, Scopus)
2019
201962. Tyrosinase and α-glucosidase inhibitory potential of compounds isolated from Quercus coccifera bark: In vitro and in silico perspectives
SARI S., BARUT B., ÖZEL A., Kuruüzüm-Uz A., ŞÖHRETOĞLU D.
Bioorganic Chemistry
, cilt.86, ss.296-304, 2019 (SCI-Expanded, Scopus)
2019
201963. Synthesis, anticonvulsant screening, and molecular modeling studies of new arylalkylimidazole oxime ether derivatives
ÖZDEMİR Z., SARI S., KARAKURT A., DALKARA S.
Drug Development Research
, cilt.80, sa.2, ss.269-280, 2019 (SCI-Expanded, Scopus)
2019
201964. Class I histone deacetylase inhibition by aryl butenoic acid derivatives: In silico and in vitro studies
BORA G., SARI S., Taskor G., DALKARA S., Erdem-Yurter H.
JOURNAL OF RESEARCH IN PHARMACY
, cilt.23, sa.5, ss.952-959, 2019 (ESCI, Scopus, TRDizin)
2018
201865. α-Glucosidase inhibitory effects of polyphenols from Geranium asphodeloides: Inhibition kinetics and mechanistic insights through in vitro and in silico studies
RENDA G., SARI S., BARUT B., ŠORAL M., LIPTAJ T., KORKMAZ B., et al.
Bioorganic Chemistry
, cilt.81, ss.545-552, 2018 (SCI-Expanded, Scopus)
2018
201866. Tyrosinase inhibition by some flavonoids: Inhibitory activity, mechanism by in vitro and in silico studies
ŞÖHRETOĞLU D., SARI S., BARUT B., ÖZEL A.
Bioorganic Chemistry
, cilt.81, ss.168-174, 2018 (SCI-Expanded, Scopus)
2018
201867. Synthesis and anticonvulsant screening of 1,2,4-triazole derivatives
SARI S., KAYNAK F. B., DALKARA S.
Pharmacological Reports
, cilt.70, sa.6, ss.1116-1123, 2018 (SCI-Expanded, Scopus)
2018
201868. Tyrosinase inhibition by a rare neolignan: Inhibition kinetics and mechanistic insights through in vitro and in silico studies
ŞÖHRETOĞLU D., SARI S., BARUT B., ÖZEL A.
Computational Biology and Chemistry
, cilt.76, ss.61-66, 2018 (SCI-Expanded, Scopus)
2018
201869. Discovery of potent alpha-glucosidase inhibitor flavonols: Insights into mechanism of action through inhibition kinetics and docking simulations
ŞÖHRETOĞLU D., SARI S., BARUT B., ÖZEL A.
BIOORGANIC CHEMISTRY
, cilt.79, ss.257-264, 2018 (SCI-Expanded, Scopus)
2018
201870. Synthesis, anticonvulsant activity, and molecular modeling studies of novel 1-phenyl/1-(4-chlorophenyl)-2-(1H-triazol-1-yl)ethanol ester derivatives
DOĞAN İ. S., ÖZDEMİR Z., SARI S., Bozbey İ., KARAKURT A., Saraç S.
Medicinal Chemistry Research
, cilt.27, sa.9, ss.2171-2186, 2018 (SCI-Expanded, Scopus)
2018
201871. Potential of Potentilla inclinata and its polyphenolic compounds in α-glucosidase inhibition: Kinetics and interaction mechanism merged with docking simulations
ŞÖHRETOĞLU D., SARI S., ŠORAL M., BARUT B., ÖZEL A., LIPTAJ T.
International Journal of Biological Macromolecules
, cilt.108, ss.81-87, 2018 (SCI-Expanded, Scopus)
2017
201772. GPCR Modulation of Thieno[2,3-b]pyridine Anti-Proliferative Agents
Zafar A., SARI S., Leung E., Pilkington L. I., Van Rensburg M., Barker D., et al.
MOLECULES
, cilt.22, sa.12, 2017 (SCI-Expanded, Scopus)
2017
201773. alpha-Glucosidase inhibitory effect of Potentilla astracanica and some isoflavones: Inhibition kinetics and mechanistic insights through in vitro and in silico studies
ŞÖHRETOĞLU D., SARI S., ÖZEL A., BARUT B.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
, cilt.105, ss.1062-1070, 2017 (SCI-Expanded, Scopus)
2017
201774. Design, synthesis, and molecular modeling of new 3(2H)-pyridazinone derivatives as acetylcholinesterase/butyrylcholinesterase inhibitors
ÖZDEMİR Z., Yılmaz H., SARI S., KARAKURT A., Şenol F. S., Uysal M.
Medicinal Chemistry Research
, cilt.26, sa.10, ss.2293-2308, 2017 (SCI-Expanded, Scopus)
2017
201775. New Anti-Seizure (Arylalkyl)azole Derivatives: Synthesis, In Vivo and In Silico Studies
SARI S., DALKARA S., KAYNAK F. B., REYNISSON J., Sarac S., KARAKURT A.
ARCHIV DER PHARMAZIE
, cilt.350, sa.6, 2017 (SCI-Expanded, Scopus)
2017
201776. New azole derivatives showing antimicrobial effects and their mechanism of antifungal activity by molecular modeling studies
DOGAN I. S., SARAC S., SARI S., KART D., Gokhan S. E., VURAL İ., et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
, cilt.130, ss.124-138, 2017 (SCI-Expanded, Scopus)
2016
201677. New (arylalkyl)azole derivatives showing anticonvulsant effects could have VGSC and/or GABA(A)R affinity according to molecular modeling studies
SARI S., KARAKURT A., USLU H., KAYNAK F. B., Calis U., DALKARA S.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
, cilt.124, ss.407-416, 2016 (SCI-Expanded, Scopus)
2016
201678. Coumarin or benzoxazinone based novel carbonic anhydrase inhibitors: synthesis, molecular docking and anticonvulsant studies
Karataş M. O., Uslu H., SARI S., Alagöz M. A., Karakurt A., Alıcı B., et al.
JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY , cilt.31, sa.5, ss.760-772, 2016 (SCI-Expanded, Scopus)
Hakemli Bilimsel Toplantılarda Yayımlanmış Bildiriler
2023
20231. Investigation of the Effect of Heroin on Glutathione Metabolism at the Metabolomic Level
Catak S., SABUNCUOĞLU S., SARI S., NEMUTLU E.
57th Congress of the European-Societies-of-Toxicology (EUROTOX), Ljubljana, Slovenya, 10 - 13 Eylül 2023, cilt.384, (Özet Bildiri)
2021
20212. Hepatosellüler kanserde YAP proteini hedefli yeni bileşiklerin belirlenmesi
GÜNTEKİN ERGÜN S., SARI S., AVCI A., DİNÇER P. R.
17. Ulusal Tıbbi Biyoloji ve Genetik Kongresi, 28 - 31 Ekim 2021, (Özet Bildiri)
2018
20183. Tyrosinase inhibition by a Rare Neolignan: An in vitro and in silico study
ŞÖHRETOĞLU D., SARI S., BARUT B., ÖZEL A.
Internation Symposium on Medicinal Chemistry, 6 - 10 Eylül 2018, (Özet Bildiri)
2018
20184. Discovery of potent α-glucosidase inhibitor flavonols: Insights into mechanism of action through inhibition kinetics and docking simulations
ŞÖHRETOĞLU D., SARI S., BARUT B., ÖZEL A.
advances in Phytochemical Analysis (Trends in Natural Products Research), 2 - 05 Temmuz 2018, (Özet Bildiri)
2018
20185. Hacettepe Üniversitesi Eczacılık Fakültesi’nin Akreditasyon Süreci Açısından 2016 ve 2017 Yılı Değerlendirmesi
ERDOĞAR N., DOĞAN A., BİBEROĞLU K., ULUTAŞ DENİZ E., EROĞLU İ., KAZKAYASI İ., et al.
II. Ulusal Eczacılık Eğitimi ve Akreditasyon Kongresi, Türkiye, 10 - 11 Mayıs 2018, (Özet Bildiri)
2018
20186. Hacettepe Üniversitesi Eczacılık Fakültesi’nin Akreditasyon Sonrasında Standartları Karşılama Açısından Son Üç Yıldaki Mevcut Durumu
ERDOĞAR N., DOĞAN A., BİBEROĞLU K., ULUTAŞ DENİZ E., EROĞLU İ., KAZKAYASI İ., et al.
II. Ulusal Eczacılık Eğitimi ve Akreditasyon Kongresi, Türkiye, 10 - 11 Mayıs 2018, (Özet Bildiri)
2017
20177. Discovery of New Azole Antifungals with Potent Activity against Clinically Resistant Candida tropicalis Isolate and Biofilm Formation
SARI S., KART D., SARAÇ TARHAN S., KARAKURT A., EŞSİZ GÖKHAN Ş., DALKARA S.
5th International BAU Drug Design Congress, İstanbul, Türkiye, 19 - 21 Ekim 2017, (Özet Bildiri)
2017
20178. Studies on New 1-Phenyl-2-(1H-imidazol-1-yl)ethanone Oxime Esters as Potential Antifungal Compounds
AKANSEL S., SARI S., SARAÇ TARHAN S., KART D., KARAKURT A., DALKARA S.
3rd International Multidisciplinary Symposium on Drug Research and Development, 5 - 07 Ekim 2017, (Özet Bildiri)
2017
20179. New Azoles in Oxime Ester Structure: Antifungal Susceptibility, Anti-Biofilm Activity, and Molecular Modeling Studies
SARI S., KART D., SARAÇ TARHAN S., KARAKURT A., DALKARA S.
3rd International Multidisciplinary Symposium on Drug Research and Development, 5 - 07 Ekim 2017, (Özet Bildiri)
2017
201710. Synthesis, Biological Activity, and Molecular Modelling Studies on New Oxime Ether Compounds Bearing Imidazole Ring
BOZBEY İ., ÖZDEMİR Z., SARI S., KART D., KARAKURT A., SARAÇ TARHAN S., et al.
International Multidisciplinary Symposium on Drug Research and Development (DRD 2017), Erzurum, Türkiye, 5 - 07 Ekim 2017, (Özet Bildiri)
2017
201711. Discovery of Novel Azole Antifungals: An In Silico and In Vitro Study
SARI S., KART D., EŞSİZ GÖKHAN Ş., KARAKURT A., SARAÇ TARHAN S., DALKARA S.
7th EFMC International Symposium on Advances in Synthetic and Medicinal Chemistry, VİYANA, Avusturya, 27 - 31 Ağustos 2017, (Özet Bildiri)
2015
201512. Hypofractionated Stereotactic Radiation Therapy/Radiosurgery Results in Patients With Uveal Melanoma
YAZICI G., ÖZYİĞİT G., SARI S., TARLAN B., KIRATLI H., CENGİZ M., et al.
57th Annual Meeting of the American-Society-for-Radiation-Oncology (ASTRO), San-Antonio, Kuzey Mariana Adaları, 18 - 21 Ekim 2015, cilt.93, (Özet Bildiri)
Kitaplar
2024
20241. Computaonal Approaches to Phytochemical Drug Discovery
SARI S., ŞÖHRETOĞLU D.
Computational Phytochemistry, Nahar Lutfun, Sarker Satyajit D., Editör, Elsevier, Amsterdam, ss.395-412, 2024
2021
20212. Chapter 7 - Flavonoids as Inducers of Apoptosis and Autophagy in Breast Cancer
Şöhretoğlu D., Sarı S.
Discovery and Development of Anti-Breast Cancer Agents from Natural Products, Goutam Brahmachari, Editör, Elsevier Science, Oxford/Amsterdam , Oxford, ss.147-196, 2021
2021
20213. Flavonoids as Inducers of Apoptosis and Autophagy in Breast Cancer
ŞÖHRETOĞLU D., Arroo R., SARI S., Huang S.
Discovery and Development of Anti-Breast Cancer Agents from Natural Products, Brahmachari Goutam, Editör, Elsevier, ss.147-196, 2021
Desteklenen Projeler
2015 - Devam Ediyor
2015 - Devam EdiyorPotansiyel Antifungal Ve Antikonvülsan Etkili Yeni Azol Bileşikleri Moleküler Modelleme Sentez Ve Biyolojik Aktivite Çalışmaları
TÜBİTAK Projesi
2021 - 2023
2021 - 2023Yeni HİF PHD2 inhibitörlerinin yüksek verimli sanal aktivite tarama ile keşfi ve hücre düzeyinde validasyonu
Yükseköğretim Kurumları Destekli Proje , BAP Diğer
SARI S. (Yürütücü)
2020 - 2022
2020 - 2022Yeni antifungal bileşiklerin ligand ve yapı temelli sanal aktivite tarama yöntemi ile keşfi
Yükseköğretim Kurumları Destekli Proje , BAP Diğer
SARI S. (Yürütücü), SABUNCUOĞLU S., ARIKAN AKDAĞLI S., GÜLMEZ KIVANÇ D., KART D.
2017 - 2022
2017 - 2022Aril bütenoik asit türevlerinin HDAC-spesifik inhibisyon aktivitelerinin ve nöroprotektif etkilerinin araştırılması
Yükseköğretim Kurumları Destekli Proje , BAP Araştırma Projesi
YURTER H. (Yürütücü), BORA G., TAŞKOR G., DALKARA S., SARI S., Sunguroğlu M.
2020 - 2021
2020 - 2021Potentilla speciosa Willd var speciosa Willd ve sekonder metabolitlerinin glukozidaz ve tirosinaz inhibitör etkilerinin araştırılması
Yükseköğretim Kurumları Destekli Proje , BAP Y.Lisans
ŞÖHRETOĞLU D. (Yürütücü), Özgünseven A., SARI S.
2020 - 2021
2020 - 2021İlaç Yeniden Konumlandırma Yaklaşımı ile Alfa Tübülin Asetilasyonunu Arttırabilecek Bileşiklerin Araştırılması
Yükseköğretim Kurumları Destekli Proje , BAP Y.Lisans
BORA AKOĞLU G. (Yürütücü), YURTER H., Çetin Ö., SARI S.
2019 - 2020
2019 - 2020Kurum içi bir azol kütüphanesi içerisinden sanal aktivite tarama ile yeni alfa-glukozidaz inhibitörü bileşiklerin keşfi
Yükseköğretim Kurumları Destekli Proje , BAP Diğer
SARI S. (Yürütücü), SARAÇ TARHAN S., ÖZEL A., BARUT B.
2018 - 2020
2018 - 2020Polidatin ve Kirsosplenetinin DNA Bağlanma Modları Topoizomeraz Enzim İnhibitörü Etkilerinin In vitro ve In siliko Araştırılması
Yükseköğretim Kurumları Destekli Proje , BAP Diğer
ŞÖHRETOĞLU D. (Yürütücü), BARUT B., SARI S., ÖZEN A.
2018 - 2020
2018 - 2020Oksim ester yapısında arilalkilazol türevi antifungal bileşikler (Amerika Başvurusu)
Yükseköğretim Kurumları Destekli Proje , BAP Diğer
SARAÇ TARHAN S. (Yürütücü), SARI S., DALKARA S., KARAKURT A.
2018 - 2019
2018 - 2019Bazı Flavonoitlerin alpha-Glukozidaz ve Tirosinaz Enzim İnhibitörü Etki Mekanizmalarının Kinetik ve Bilgisayarlı Modelleme Yöntemleriyle In vitro ve In Silico Araştırılması
Yükseköğretim Kurumları Destekli Proje , BAP Diğer
ŞÖHRETOĞLU D. (Yürütücü), SARI S., BARUT B., ÖZEL A.
2017 - 2018
2017 - 2018Arilalkilazol Yapısında Yeni Oksim Ester Türevleri Üzerinde Çalışmalar Sentez Biyolojik Aktivite ve Moleküler Modelleme
Yükseköğretim Kurumları Destekli Proje , BAP Doktora
ÖZKANLI F. (Yürütücü), SARI S.
2015 - 2018
2015 - 2018Oksim ester yapısında arilalkilazol türevi antifungal bileşikler (PCT başvurusu)
Yükseköğretim Kurumları Destekli Proje , BAP Diğer
SARAÇ TARHAN S. (Yürütücü), SARI S., KARAKURT A., DALKARA S.
2017 - 2017
2017 - 2017EUROPIN Viyana İlaç Tasarımı Yaz Okulu 2017
Yükseköğretim Kurumları Destekli Proje , BAP Diğer
DALKARA S. (Yürütücü), SARI S.
Patent
2016
2016Oksim Ester Yapısında (Arilalkil)azol Türevi Antifungal Bileşikler
Patent
Tescil Edildi, Buluşun Tescil No: TR 2013 11057 B , Standart Tescil