Synthesis and cytotoxicity studies on new pyrazole-containing oxime ester derivatives

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KARAKURT A., Bozbey I., USLU H., SARI S., ÖZDEMİR Z., ŞALVA E.

TROPICAL JOURNAL OF PHARMACEUTICAL RESEARCH, vol.18, no.6, pp.1315-1322, 2019 (SCI-Expanded)

• Publication Type: Article / Article
• Volume: 18 Issue: 6
• Publication Date: 2019
• Doi Number: 10.4314/tjpr.v18i6.24
• Journal Name: TROPICAL JOURNAL OF PHARMACEUTICAL RESEARCH
• Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
• Page Numbers: pp.1315-1322
• Hacettepe University Affiliated: Yes

Abstract

Purpose: To synthesize a series of new 1-(2-naphthyl)-2-(1H-pyrazol-1-yl)ethanone oxime ester derivatives (5-12) with potential anticancer properties, and to determine their cytotoxic effects in mouse fibroblast and human neuroblastoma cell lines.