Synthesis and cytotoxicity studies on new pyrazole-containing oxime ester derivatives


KARAKURT A., Bozbey I., USLU H., SARI S. , ÖZDEMİR Z., ŞALVA E.

TROPICAL JOURNAL OF PHARMACEUTICAL RESEARCH, vol.18, no.6, pp.1315-1322, 2019 (Journal Indexed in SCI) identifier identifier

  • Publication Type: Article / Article
  • Volume: 18 Issue: 6
  • Publication Date: 2019
  • Doi Number: 10.4314/tjpr.v18i6.24
  • Title of Journal : TROPICAL JOURNAL OF PHARMACEUTICAL RESEARCH
  • Page Numbers: pp.1315-1322

Abstract

Purpose: To synthesize a series of new 1-(2-naphthyl)-2-(1H-pyrazol-1-yl)ethanone oxime ester derivatives (5-12) with potential anticancer properties, and to determine their cytotoxic effects in mouse fibroblast and human neuroblastoma cell lines.