Prof. Dr. TUNCA DOĞAN
Ana Sayfa
Eğitim Bilgileri
Araştırma Alanları
Akademik İdari Deneyim
Yayınlar & Eserler
Proje & Patent & Tasarım
Bilimsel & Mesleki Faaliyetler
Başarılar & Tanınırlık
Duyurular & Dokümanlar
İletişim
Özgeçmiş Dosyası İndir
Türkçe
English
Hacettepe Üniversitesi
Akademik Veri Yönetim Sistemi
English
Akademik Veri Yönetim Sistemi
English
Yayınlar & Eserler
Yayın Ağı
SCI, SSCI ve AHCI İndekslerine Giren Dergilerde Yayınlanan Makaleler
Design, synthesis, and evaluation of novel Indole-Based small molecules as sirtuin inhibitors with anticancer activities
BINARCI B.
,
Kilic E. K.
,
DOĞAN T.
,
ATALAY R.
,
KAHRAMAN D. C.
,
BAYTAŞ S.
DRUG DEVELOPMENT RESEARCH
, sa.7, 2024 (SCI-Expanded)
Mutual annotation-based prediction of protein domain functions with Domain2GO
Ulusoy E.
,
DOĞAN T.
PROTEIN SCIENCE
, sa.6, 2024 (SCI-Expanded)
An integrative framework for clinical diagnosis and knowledge discovery from exome sequencing data
Shojaei M.
,
Mohammadvand N.
,
DOĞAN T.
,
Alkan C.
,
Çetin Atalay R.
,
ACAR A.
Computers in Biology and Medicine
, cilt.169, 2024 (SCI-Expanded)
How to approach machine learning-based prediction of drug/compound–target interactions
Atas Guvenilir H.
,
DOĞAN T.
Journal of Cheminformatics
, cilt.15, sa.1, 2023 (SCI-Expanded)
Democratizing knowledge representation with BioCypher
Lobentanzer S.
,
Aloy P.
,
Baumbach J.
,
Bohar B.
,
Carey V. J.
,
Charoentong P.
, et al.
Nature Biotechnology
, cilt.41, sa.8, ss.1056-1059, 2023 (SCI-Expanded)
SELFormer: molecular representation learning via SELFIES language models
Yüksel A.
,
Ulusoy E.
,
Ünlü A.
,
DOĞAN T.
Machine Learning: Science and Technology
, cilt.4, sa.2, 2023 (SCI-Expanded)
ProFAB-open protein functional annotation benchmark
Özdilek A. S.
,
ATAKAN A.
,
ÖZSARI G.
,
Acar A.
,
ATALAY M. V.
,
DOĞAN T.
, et al.
Briefings in bioinformatics
, cilt.24, sa.2, 2023 (SCI-Expanded)
UniProt: the Universal Protein Knowledgebase in 2023
Bateman A.
,
Martin M.
,
Orchard S.
,
Magrane M.
,
Ahmad S.
,
Alpi E.
, et al.
Nucleic Acids Research
, cilt.51, sa.D1, 2023 (SCI-Expanded)
ASCARIS: Positional feature annotation and protein structure-based representation of single amino acid variations
Cankara F.
,
DOĞAN T.
Computational and Structural Biotechnology Journal
, cilt.21, ss.4743-4758, 2023 (SCI-Expanded)
SLPred: a multi-view subcellular localization prediction tool for multi-location human proteins
ÖZSARI G.
,
RİFAİOĞLU A. S.
,
ATAKAN A.
,
Tunca Dogan T.
,
Martin M. J.
,
ATALAY R.
, et al.
BIOINFORMATICS
, cilt.38, sa.17, ss.4226-4229, 2022 (SCI-Expanded)
Learning functional properties of proteins with language models
Unsal S.
,
Atas H.
,
Albayrak M.
,
Turhan K.
,
Acar A. C.
,
Doğan T.
NATURE MACHINE INTELLIGENCE
, cilt.4, sa.3, ss.227-245, 2022 (SCI-Expanded)
Machine learning-based prediction of drug approvals using molecular, physicochemical, clinical trial, and patent-related features
Ciray F.
,
DOĞAN T.
Expert Opinion on Drug Discovery
, cilt.17, sa.12, ss.1425-1441, 2022 (SCI-Expanded)
Editorial: Machine Learning Methodologies to Study Molecular Interactions
Yakimovich A.
,
oezguer A.
,
DOĞAN T.
,
Ozkirimli E.
FRONTIERS IN MOLECULAR BIOSCIENCES
, cilt.8, 2021 (SCI-Expanded)
A crowdsourcing open platform for literature curation in UniProt
Wang Y.
,
Wang Q.
,
Huang H.
,
Huang W.
,
Chen Y.
,
McGarvey P. B.
, et al.
PLOS BIOLOGY
, cilt.19, sa.12, 2021 (SCI-Expanded)
Protein domain-based prediction of drug/compound-target interactions and experimental validation on LIM kinases
Doğan T.
,
Guzelcan E. A.
,
Baumann M.
,
Koyas A.
,
Atas H.
,
Baxendale I.
, et al.
PLOS COMPUTATIONAL BIOLOGY
, cilt.17, sa.11, 2021 (SCI-Expanded)
CROssBAR: comprehensive resource of biomedical relations with knowledge graph representations
Doğan T.
,
Atas H.
,
Joshi V.
,
Atakan A.
,
Rifaioğlu A. S.
,
Nalbat E.
, et al.
NUCLEIC ACIDS RESEARCH
, cilt.49, sa.16, 2021 (SCI-Expanded)
Crowdsourced mapping of unexplored target space of kinase inhibitors
Cichonska A.
,
Ravikumar B.
,
Allaway R. J.
,
Wan F.
,
Park S.
,
Isayev O.
, et al.
NATURE COMMUNICATIONS
, cilt.12, sa.1, 2021 (SCI-Expanded)
MDeePred: novel multi-channel protein featurization for deep learning-based binding affinity prediction in drug discovery
Rifaioglu A. S.
,
Atalay R. C.
,
KAHRAMAN D. C.
,
DOĞAN T.
,
Martin M.
,
Atalay V.
BIOINFORMATICS
, cilt.37, sa.5, ss.693-704, 2021 (SCI-Expanded)
UniProt: the universal protein knowledgebase in 2021
Bateman A.
,
Martin M.
,
Orchard S.
,
Magrane M.
,
Agivetova R.
,
Ahmad S.
, et al.
NUCLEIC ACIDS RESEARCH
, cilt.49, sa.D1, 2021 (SCI-Expanded)
iBioProVis: interactive visualization and analysis of compound bioactivity space
DÖNMEZ A.
,
RİFAİOĞLU A. S.
,
ACAR A. C.
,
DOĞAN T.
,
ATALAY R.
,
ATALAY M. V.
BIOINFORMATICS
, cilt.36, sa.14, ss.4227-4230, 2020 (SCI-Expanded)
DEEPScreen: high performance drug-target interaction prediction with convolutional neural networks using 2-D structural compound representations
Rifaioğlu A. S.
,
Nalbat E.
,
Atalay V.
,
Martin M. J.
,
Cetin-Atalay R.
,
Doğan T.
CHEMICAL SCIENCE
, cilt.11, sa.9, ss.2531-2557, 2020 (SCI-Expanded)
The CAFA challenge reports improved protein function prediction and new functional annotations for hundreds of genes through experimental screens
Zhou N.
,
Jiang Y.
,
Bergquist T. R.
,
Lee A. J.
,
Kacsoh B. Z.
,
Crocker A. W.
, et al.
GENOME BIOLOGY
, cilt.20, sa.1, 2019 (SCI-Expanded)
FAIR adoption, assessment and challenges at UniProt
Garcia L.
,
Bolleman J.
,
Gehant S.
,
Redaschi N.
,
Martin M.
,
Bateman A.
, et al.
SCIENTIFIC DATA
, cilt.6, 2019 (SCI-Expanded)
Recent applications of deep learning and machine intelligence on in silico drug discovery: methods, tools and databases
Rifaioğlu A. S.
,
Atas H.
,
Martin M. J.
,
Cetin-Atalay R.
,
Atalay V.
,
Dogan T.
BRIEFINGS IN BIOINFORMATICS
, cilt.20, sa.5, ss.1878-1912, 2019 (SCI-Expanded)
DEEPred: Automated Protein Function Prediction with Multi-task Feed-forward Deep Neural Networks
Rifaioğlu A. S.
,
Doğan T.
,
Martin M. J.
,
Cetin-Atalay R.
,
Atalay V.
SCIENTIFIC REPORTS
, cilt.9, 2019 (SCI-Expanded)
UniProt: a worldwide hub of protein knowledge
Bateman A.
,
Martin M.
,
Orchard S.
,
Magrane M.
,
Alpi E.
,
Bely B.
, et al.
NUCLEIC ACIDS RESEARCH
, cilt.47, 2019 (SCI-Expanded)
ECPred: a tool for the prediction of the enzymatic functions of protein sequences based on the EC nomenclature
Dalkiran A.
,
Rifaioğlu A. S.
,
Martin M. J.
,
Cetin-Atalay R.
,
Atalay V.
,
Dogan T.
BMC BIOINFORMATICS
, cilt.19, 2018 (SCI-Expanded)
HPO2GO: prediction of human phenotype ontology term associations for proteins using cross ontology annotation co-occurrences
Doğan T.
PEERJ
, cilt.6, 2018 (SCI-Expanded)
Large-scale automated function prediction of protein sequences and an experimental case study validation on PTEN transcript variants
Rifaioğlu A. S.
,
Dogan T.
,
Sarac O. S.
,
Ersahin T.
,
Saidi R.
,
Atalay M. V.
, et al.
PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS
, cilt.86, sa.2, ss.135-151, 2018 (SCI-Expanded)
A Structural Perspective on the Modulation of Protein-protein Interactions with Small Molecules
Demirel H. C.
,
Dogan T.
,
TUNÇBAĞ N.
CURRENT TOPICS IN MEDICINAL CHEMISTRY
, cilt.18, sa.8, ss.700-713, 2018 (SCI-Expanded)
Phylogenetic and Other Conservation-Based Approaches to Predict Protein Functional Sites
Atas H.
,
Tunçbağ N.
,
Doğan T.
COMPUTATIONAL DRUG DISCOVERY AND DESIGN
, cilt.1762, ss.51-69, 2018 (SCI-Expanded)
On expert curation and scalability: UniProtKB/Swiss-Prot as a case study
Poux S.
,
Arighi C. N.
,
Magrane M.
,
Bateman A.
,
Wei C.
,
Lu Z.
, et al.
BIOINFORMATICS
, cilt.33, sa.21, ss.3454-3460, 2017 (SCI-Expanded)
From the research laboratory to the database: the Caenorhabditis elegans kinome in UniProtKB
Zaru R.
,
Magrane M.
,
O'Donovan C.
,
Bateman A.
,
Martin M. J.
,
Alpi E.
, et al.
BIOCHEMICAL JOURNAL
, cilt.474, ss.493-515, 2017 (SCI-Expanded)
UniProt: the universal protein knowledgebase
Bateman A.
,
Martin M. J.
,
O'Donovan C.
,
Magrane M.
,
Alpi E.
,
Antunes R.
, et al.
NUCLEIC ACIDS RESEARCH
, cilt.45, 2017 (SCI-Expanded)
An expanded evaluation of protein function prediction methods shows an improvement in accuracy
Jiang Y.
,
Oron T. R.
,
Clark W. T.
,
Bankapur A. R.
,
D'Andrea D.
,
Lepore R.
, et al.
GENOME BIOLOGY
, cilt.17, 2016 (SCI-Expanded)
UniProt-DAAC: domain architecture alignment and classification, a new method for automatic functional annotation in UniProtKB
Doğan T.
,
Macdougall A.
,
Saidi R.
,
Poggioli D.
,
Bateman A.
,
O'donovan C.
, et al.
BIOINFORMATICS
, cilt.32, sa.15, ss.2264-2271, 2016 (SCI-Expanded)
The UniProtKB guide to the human proteome
Breuza L.
,
Poux S.
,
Estreicher A.
,
Famiglietti M. L.
,
Magrane M.
,
Tognolli M.
, et al.
DATABASE-THE JOURNAL OF BIOLOGICAL DATABASES AND CURATION
, 2016 (SCI-Expanded)
Tools and data services registry: a community effort to document bioinformatics resources
Ison J.
,
Rapacki K.
,
Menager H.
,
Kalas M.
,
Rydza E.
,
Chmura P.
, et al.
NUCLEIC ACIDS RESEARCH
, cilt.44, 2016 (SCI-Expanded)
UniProt: a hub for protein information
Bateman A.
,
Martin M. J.
,
O'Donovan C.
,
Magrane M.
,
Apweiler R.
,
Alpi E.
, et al.
NUCLEIC ACIDS RESEARCH
, cilt.43, 2015 (SCI-Expanded)
Activities at the Universal Protein Resource (UniProt)
Apweiler R.
,
Bateman A.
,
Martin M. J.
,
O'Donovan C.
,
Magrane M.
,
Alam-Faruque Y.
, et al.
NUCLEIC ACIDS RESEARCH
, cilt.42, 2014 (SCI-Expanded)
Automatic Identification of Highly Conserved Family Regions and Relationships in Genome Wide Datasets Including Remote Protein Sequences
Doğan T.
,
Karacali B.
PLOS ONE
, cilt.8, sa.9, 2013 (SCI-Expanded)
Diğer Dergilerde Yayınlanan Makaleler
Transfer learning for drug-target interaction prediction
DALKIRAN A.
,
ATAKAN A.
,
Rifaioğlu A. S.
,
Martin M. J.
,
Atalay R. Ç.
,
ACAR A.
, et al.
Bioinformatics (Oxford, England)
, cilt.39, sa.39, 2023 (Scopus)
Data Centric Molecular Analysis and Evaluation of Hepatocellular Carcinoma Therapeutics Using Machine Intelligence-Based Tools
Cetin-Atalay R.
,
Kahraman D. C.
,
Nalbat E.
,
Rifaioğlu A. S.
,
Atakan A.
,
Dönmez A.
, et al.
JOURNAL OF GASTROINTESTINAL CANCER
, cilt.52, sa.4, ss.1266-1276, 2021 (Hakemli Dergi)
Hakemli Kongre / Sempozyum Bildiri Kitaplarında Yer Alan Yayınlar
In vitro validation of drug-target interactions revealed in silico by Comprehensive Resource of Biomedical Relations with Network Representations and Deep Learning (CROssBAR) in HCC
NALBAT E.
,
Rifaioglu A. S.
,
DOĞAN T.
,
Martin M. J.
,
Cetin-Atalay R.
,
ATALAY M. V.
AACR Annual Meeting, ELECTR NETWORK, 22 - 24 Haziran 2020, cilt.80
Unsupervised identification of redundant domain entries in InterPro database using clustering techniques
RİFAİOĞLU A. S.
,
Doǧan T.
,
CAN T.
6th ACM Conference on Bioinformatics, Computational Biology, and Health Informatics, BCB 2015, Georgia, Amerika Birleşik Devletleri, 9 - 12 Eylül 2015, ss.505-506
2-D thresholding of the connectivity map following the multiple sequence alignments of diverse datasets
Doǧan T.
,
Karaçali B.
10th IASTED International Conference on Biomedical Engineering, BioMed 2013, Innsbruck, Avusturya, 13 - 15 Şubat 2013, ss.1-8
Evolutionary relationships between gene sequences via nonlinear embedding Doǧrusal olmayan gömme teknikleri altinda gen dizilerinin evrimsel i̇lişkileri
Doǧan T.
,
Karaçcali B.
2010 15th National Biomedical Engineering Meeting, BIYOMUT2010, Antalya, Türkiye, 21 - 24 Nisan 2010
Metrikler
Daha fazla metrik
Yayın
48
Atıf (WoS)
17299
H-İndeks (WoS)
21
Atıf (Scopus)
22060
H-İndeks (Scopus)
21
Atıf (Scholar)
30963
H-İndeks (Scholar)
25
Proje
10
Açık Erişim
23
BM Sürdürülebilir Kalkınma Amaçları