On expert curation and scalability: UniProtKB/Swiss-Prot as a case study

Creative Commons License

Poux S., Arighi C. N., Magrane M., Bateman A., Wei C., Lu Z., ...More

BIOINFORMATICS, vol.33, no.21, pp.3454-3460, 2017 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 33 Issue: 21
  • Publication Date: 2017
  • Doi Number: 10.1093/bioinformatics/btx439
  • Journal Name: BIOINFORMATICS
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.3454-3460
  • Hacettepe University Affiliated: No


Motivation: Biological knowledgebases, such as UniProtKB/Swiss-Prot, constitute an essential component of daily scientific research by offering distilled, summarized and computable knowledge extracted from the literature by expert curators. While knowledgebases play an increasingly important role in the scientific community, their ability to keep up with the growth of biomedical literature is under scrutiny. Using UniProtKB/Swiss-Prot as a case study, we address this concern via multiple literature triage approaches.