UniProt-DAAC: domain architecture alignment and classification, a new method for automatic functional annotation in UniProtKB

Dogan T. , MacDougall A., Saidi R., Poggioli D., Bateman A., O'Donovan C., ...More

BIOINFORMATICS, vol.32, no.15, pp.2264-2271, 2016 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 32 Issue: 15
  • Publication Date: 2016
  • Doi Number: 10.1093/bioinformatics/btw114
  • Title of Journal : BIOINFORMATICS
  • Page Numbers: pp.2264-2271


Motivation: Similarity-based methods have been widely used in order to infer the properties of genes and gene products containing little or no experimental annotation. New approaches that overcome the limitations of methods that rely solely upon sequence similarity are attracting increased attention. One of these novel approaches is to use the organization of the structural domains in proteins.