UniProt-DAAC: domain architecture alignment and classification, a new method for automatic functional annotation in UniProtKB


Dogan T. , MacDougall A., Saidi R., Poggioli D., Bateman A., O'Donovan C., ...Daha Fazla

BIOINFORMATICS, cilt.32, sa.15, ss.2264-2271, 2016 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 32 Konu: 15
  • Basım Tarihi: 2016
  • Doi Numarası: 10.1093/bioinformatics/btw114
  • Dergi Adı: BIOINFORMATICS
  • Sayfa Sayıları: ss.2264-2271

Özet

Motivation: Similarity-based methods have been widely used in order to infer the properties of genes and gene products containing little or no experimental annotation. New approaches that overcome the limitations of methods that rely solely upon sequence similarity are attracting increased attention. One of these novel approaches is to use the organization of the structural domains in proteins.