Assoc. Prof. GÖKÇEN TELLİ

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Publication

Publication (WoS)

Publication (Scopus)

Citation (WoS)

H-Index (WoS)

Citation (Scopus)

H-Index (Scopus)

Project

Open Access

UN Sustainable Development Goals

Education

2011 - 2017

Doctorate

Hacettepe University, Eczacılık Fak./ Sağlık Bilimleri Ens./Farmakoloji, Eczacılık/Farmakoloji, Turkey

2006 - 2011

Undergraduate

Hacettepe University, Eczacılık Fakültesi, Turkey

Dissertations

2017

Doctorate

Normaksik ve kronik hipoksik sıçanlarda intermedin’in (IMD/AM2) pulmoner vasküler yatağa etkisinin araştırılması

Hacettepe University, Eczacılık Fakültesi, Eczacılık Meslek Bilimleri Bölümü

Foreign Languages

A2 Elementary

Spanish

B2 Upper Intermediate

English

Certificates, Courses and Trainings

2018

Proje Geliştirme Eğitimi

Other

Hacettepe Üniversitesi

2012

Deney Hayvanları Kullanım Sertifikası

Vocational Course

Hacettepe Üniversitesi

Research Areas

Health Sciences

Pharmacology and Therapeutics

Professional Sciences

Pharmacology

Academic Positions

2022 - Present

Associate Professor

Hacettepe University, Eczacılık Fakültesi, Eczacılık Meslek Bilimleri Bölümü

2013 - Present

Research Assistant

Hacettepe University, Eczacılık Fakültesi, Eczacılık Meslek Bilimleri Bölümü

2017 - 2017

Research Assistant

Ege University, Faculty Of Pharmacy, Eczacılık Meslek Bilimleri Bölümü

Managerial Experience

2024 - Present

Fakülte Öz Değerlendirme Komisyonu Üyesi

Hacettepe University, Eczacılık Fakültesi, Eczacılık Meslek Bilimleri Bölümü

2023 - Present

Akademik Danışman (Farmasötik Gelişim Topluluğu)

Hacettepe University, Eczacılık Fakültesi, Eczacılık Meslek Bilimleri Bölümü

2023 - Present

Member of the Faculty Board

Hacettepe University, Eczacılık Fakültesi

2023 - Present

Internship Committee Member

Hacettepe University, Eczacılık Fakültesi, Eczacılık Meslek Bilimleri Bölümü

Non Academic Experience

2021 - 2022

Doktora Sonrası Araştırmacı

Madrid Complutense University Faculty of Medicine, Doktora Sonrası Araştırmacı

2011 - 2012

Eczacı

Monitor Medical Research and Consulting Ltd., Eczacı

Courses

Postgraduate

EFR 609 Genel Farmakoloji

Undergraduate

ECF 333 Farmakoloji III

ECF 449 Farmakoloji V

ECF 227 Farmakoloji I

Associate Degree

Tıbbi Terminoloji

Farmakoloji

İlaç Bilgisi I

İlaç Bilgisi II

Taught Courses and Trainings

2019 - 2019

Deney Hayvanları Kullanımı Modül-2 Kursu

Continuing Education Center - Certificate Program

Telli G.

Articles

2025

1. Multitarget-directed carbamate and carbamothioate derivatives: Cholinesterase and monoamine oxidase inhibition, anti-(3-amyloid (A(3) aggregation, antioxidant and blood-brain barrier permeation properties against Alzheimer's disease

Tuncel S. T., EROL GÜNAL Ş., Demir I., BAYSAL İ., ERDEM S., TELLİ G., et al.

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY , vol.298, 2025 (SCI-Expanded, Scopus)

2025

2. Synthesis and biological evaluation of novel naproxen-phenacetin triazole hybrids as promising anti-inflammatory agents with enhanced gastrointestinal tolerability

AVCI A., Tasci H., SAĞLIK ÖZKAN B. N., TELLİ G., Gokhan-Kelekci N., ÖZKAY Y., et al.

BIOORGANIC CHEMISTRY , vol.165, 2025 (SCI-Expanded)

2024

3. Methylene Blue Attenuates Impaired Cognitive Functions and Reduces Hippocampal Aβ Levels and Oxidative Stress in D-Galactose-Induced Alzheimer’s Disease Mouse Model

Kazkayasi I., TELLİ G.

Biology Bulletin , 2024 (SCI-Expanded)

2023

4. The novel KV7 channel activator URO-K10 exerts enhanced pulmonary vascular effects independent of the KCNE4 regulatory subunit

Villegas-Esguevillas M., Cho S., Vera-Zambrano A., Kwon J. W., Barreira B., Telli G., et al.

Biomedicine and Pharmacotherapy , vol.164, 2023 (SCI-Expanded)

2023

5. Sigma-1 receptor modulation fine-tunes KV1.5 channels and impacts pulmonary vascular function

Vera-Zambrano A., Baena-Nuevo M., Rinné S., Villegas-Esguevillas M., Barreira B., TELLİ G., et al.

Pharmacological Research , vol.189, 2023 (SCI-Expanded)

2022

6. Allopurinol treatment reduced vascular remodeling and improved vascular functions in monocrotaline-induced pulmonary hypertensive rats

Gokcen T., Inci K., Inci E. E., Sevgen O., Serdar U.

Pulmonary Pharmacology and Therapeutics , vol.77, 2022 (SCI-Expanded)

2022

7. Anti-inflammatory effects of oral and intraperitoneal administration of cerium oxide nanoparticles on experimental hepatic ischemia-reperfusion injury

Zengin A., ERİKÇİ A., TELLİ G., GÜMÜŞEL B., KÖSEMEHMETOĞLU K., UÇAR G., et al.

TURKISH JOURNAL OF SURGERY , vol.38, no.3, pp.255-265, 2022 (ESCI)

2022

8. Evaluation of Anti-Inflammatory Activity of Metronidazole Treatment On Carrageenan Induced Paw Edema in Mice

Kazkayası Bölük İ., Telli G.

FABAD JOURNAL OF PHARMACEUTICAL SCIENCES , vol.47, no.2, pp.175-182, 2022 (Scopus)

2022

9. Intranasal metformin treatment ameliorates cognitive functions via insulin signaling pathway in ICV-STZ-induced mice model of Alzheimer's disease

KAZKAYASI BÖLÜK İ., TELLİ G., NEMUTLU E., Uma S.

LIFE SCIENCES , vol.299, 2022 (SCI-Expanded)

2022

10. Scutellaria brevibracteata Stapf and active principles with anti-inflammatory effects through regulation of NF-κB/COX-2/iNOS pathways

DOĞAN Z., TELLİ G., TEL B. C., SARAÇOĞLU İ.

Fitoterapia , vol.158, 2022 (SCI-Expanded)

2022

11. Acute hyperglycemia causes oxidative stress which is prevented by vitamin E pretreatment in healthy rabbits

KAZKAYASI İ., TELLİ G., BALCI ÖZYURT A., UMA M. S.

JOURNAL OF RESEARCH IN PHARMACY , 2022 (Peer-Reviewed Journal)

2022

12. The Role of Metformin and Aerobic Exercise on The Hepatic Ischemia-Reperfusion Injury in Streptozotocin-Induced Diabetic Mice

TELLİ G., Telli-Atalay O.

JOURNAL OF RESEARCH IN PHARMACY , vol.26, no.3, pp.543-553, 2022 (ESCI)

2022

13. Acute hyperglycemia causes oxidative stress which is prevented by vitamin E pretreatment in healthy rabbits

Inci K., Gokcen T., Aylin B., Serdar U.

JOURNAL OF RESEARCH IN PHARMACY , vol.26, no.3, pp.534-542, 2022 (ESCI)

2021

14. Thyrotropine releasing hormone accelerates wound healing in hyperglycemia inducted mouse fibroblast cell line

DENİZALTI M., Kazkayasi I., TELLİ G.

ISTANBUL JOURNAL OF PHARMACY , vol.51, no.3, pp.313-318, 2021 (ESCI)

2021

15. The effects of allopurinol treatment in early period of monocrotaline-induced rat pulmonary hypertension model

TELLİ G., KAZKAYASI İ., Ergonul E. I., Uma S.

BRITISH JOURNAL OF PHARMACOLOGY , vol.178, no.24, pp.4967-4968, 2021 (SCI-Expanded)

2021

16. New 2-Pyrazoline and Hydrazone Derivatives as Potent and Selective Monoamine Oxidase A Inhibitors.

Salgin-Goksen U., Telli G., Erikci A., Dedecengiz E., Tel B. C., Kaynak F. B., et al.

Journal of medicinal chemistry , vol.64, no.4, pp.1989-2009, 2021 (SCI-Expanded, Scopus)

2021

17. Higher alpha-synuclein aggregate density does not lead to more severe dopaminergic cell loss in the AAV-mediated overexpression model of Parkinson's Disease: A time-course study

TEL B. C., KAZKAYASI İ., TELLİ G., Cinar E., Mutluay S. U., YALÇIN ÇAKMAKLI G., et al.

JOURNAL OF RESEARCH IN PHARMACY , vol.25, no.3, pp.352-358, 2021 (ESCI)

2021

18. The effects of 5-hydroxytryptophan on carrageenan-induced mouse paw oedemas

TELLİ G., KAZKAYASI İ., Uma S.

REVISTA DE NUTRICAO-BRAZILIAN JOURNAL OF NUTRITION , vol.34, 2021 (SCI-Expanded)

2021

19. Investigation of the relationship between chronic montelukast treatment, asthma and depression-like behavior in mice

Tel B. C., Telli G., Onder S., Nemutlu E., Bozkurt T. E.

EXPERIMENTAL AND THERAPEUTIC MEDICINE , vol.21, no.1, 2021 (SCI-Expanded)

2020

20. The Cardiopulmonary Effects of Calcitonin-Gene Related Peptide Family Kalsitonin-Geni İle İlişkili Peptit Ailesinin Kardiyopulmoner Etkileri

TELLİ G., TEL B. C., GÜMÜŞEL B.

Turkish Journal of Pharmaceutical s , vol.17, pp.349-356, 2020 (ESCI)

2018

21. Mechanism of adrenomedullin 2/intermedin mediated vasorelaxation in rat main pulmonary artery

Telli G., Eraç Y., Tel B. C., Gumusel B.

PEPTIDES , vol.103, pp.65-71, 2018 (SCI-Expanded)

2018

22. Effect of intermedin/adrenomedullin(2) on the pulmonary vascular bed in hypoxia-induced pulmonary hypertensive rats

Telli G., Tel B. C., Yersal N., Korkusuz P., Gumusel B.

LIFE SCIENCES , vol.192, pp.62-67, 2018 (SCI-Expanded)

2018

23. Effects of GPER-1 receptor activation on the reactivity of pulmonary vascular bed and its possible protective role on ischemia/reperfusion

Telli G., Tel B. C., Buyukafsar K., Gumusel B.

JOURNAL OF RESEARCH IN PHARMACY , vol.22, no.3, pp.422-428, 2018 (ESCI)

2014

24. EFFECT OF THE G PROTEIN-COUPLED ESTROGEN RECEPTOR-1 (GPER-1) ON THE CONTROL OF PULMONARY ARTERIAL PRESSURE

Telli G., Tel B., Buyukafsar K., Gumusel B.

BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY , vol.115, pp.21-22, 2014 (SCI-Expanded)

Papers Presented at Peer-Reviewed Scientific Conferences

2021

1. The Effects of Allopurinol Treatment in Early Period of Monocrotaline-Induced Rat Pulmonary Hypertension Model

TELLİ G., KAZKAYASI İ., SOMUNCUOĞLU E. İ., UMA M. S.

Pharmacology 2021-British Pharmacological Society, England, 07 September 2021, (Summary Text)

2020

2. In vitro diyabetik koşullarda protirelinin fibroblast yara iyileşmesine etkisi

KAZKAYASI İ., DENİZALTI M., TELLİ G.

International Eurasian Conference on BioTechnology and BioChemistry, Turkey, 16 December 2020, (Summary Text)

2020

3. Anti-inflammatory activity of 5-hydroxytryptophan

TELLİ G., KAZKAYASI İ., UMA M. S.

3rd International Eurasion Conference on Biological and Chemical Sciences, Turkey, 19 March 2020, (Summary Text)

2019

4. Investigation of the relationship between montelukast treatment, asthma and depression-like behavior in mice

TELLİ G., BOZKURT T. E., Onder S., NEMUTLU E., TEL B. C.

European-Respiratory-Society (ERS) International Congress, Madrid, Spain, 28 September - 02 October 2019, vol.54, (Summary Text)

2017

5. SIÇAN ANA PULMONER ARTERİNDE İNTERMEDİN/ADRENOMEDULLİN2 (IMD/AM2)’NİN HÜCRE İÇİ KALSİYUM KONSANTRASYONUNA ETKİSİNİN İNCELENMESİ

TELLİ G., ERAÇ Y., TEL B. C., GÜMÜŞEL B.

24. Ulusal Farmakoloji Kongresi, Turkey, 17 - 20 October 2017, (Summary Text)

2017

6. The Role of Potassium Channels in The Relaxation Response of Intermedin/Adrenomedullin2 (IMD/AM2) in The Rat Pulmonary Artery

TELLİ G., TEL B. C., GÜMÜŞEL B.

International Multidisciplinary Symposium on Drug Research and Development, 5 - 07 October 2017, (Summary Text)

2016

7. Intermedin/Adrenomedullin 2 (IMD/AM2) is a potent vasodilator in chronic hypoxia induced pulmonary hypertensive isolated rat lungs

TELLİ G., Kandilci H. B., TEL B. C., Gumusel B.

Experimental Biology Meeting, California, United States Of America, 2 - 06 April 2016, vol.30, (Summary Text)

2015

8. Antidepressant activity of novel selective monoamine oxidase A MAO A inhibitors 2 Pyrazoline derivatives synthesized with molecular modelling

TELLİ G., Salgın Gökşen U., ERİKÇİ A., YABANOĞLU ÇİFTÇİ S., TEL B. C., YELEKÇİ K., et al.

International Multidiciplinary Symposium on Drug Research Development 2015, 15 - 17 October 2015, (Summary Text)

2015

9. Antidepressant activity of novel selective monoamine oxidase A inhibitors 2 Pyrazoline derivatives synthesized with molecular modeling

TELLİ G., salgın gökşen u., ERİKÇİ A., YABANOĞLU ÇİFTÇİ S., TEL B. C., YELEKÇİ K., et al.

International Multidisciplinary Symposium on Drug Research & Development, 15 - 17 October 2015

2015

10. MAO Inhibitory and Antidepressant Activities of Novel 2 Pyrazoline Derivatives

Salgın Gökşen U., TELLİ G., ERİKÇİ A., YABANOĞLU ÇİFTÇİ S., TEL B. C., UÇAR G., et al.

Pharma Middle East, Dubai, United Arab Emirates, 2 - 04 November 2015, (Summary Text)

2015

11. Adeno ilişkili viral vektör aracılı Parkinson hastalığı modelinde dentat girusta aşırı alfasinüklein ifadesine bağlı bilişsel fonksiyon değişikliklerinin davranışsal ve histopatolojik değerlendirilmesi

ÇINAR E., YALÇIN ÇAKMAKLI G., Mutluay S. U., TELLİ G., KAZKAYASI İ., Ulusoy A., et al.

23. Ulusal Farmakoloji Kongresi, Turkey, 7 - 09 September 2015

2015

12. Does higher alpha-synuclein aggregate density lead to more severe dopaminergic cell loss in the AAV-mediated over-expression model of PD?

ÇINAR E., YALÇIN ÇAKMAKLI G., Mutluay S. U., TELLİ G., KAZKAYASI İ., ULUSOY A., et al.

19th International of Parkinson’s Disease and Movement Disorders, United States Of America, 14 June 2015, (Summary Text)

2015

13. Cognitive dysfunction due to over expression of alpha synuclein in hippocampus by using viral vector based approach Modeling cognitive decline in PD

TEL B. C., YALÇIN ÇAKMAKLI G., ÇINAR E., Mutluay S. U., TELLİ G., SAKA TOPÇUOĞLU E., et al.

Movement Disordes Society Meeting 2015, 14 - 18 June 2015

2015

14. Cognitive dysfunction due to over-expression of alpha-synuclein in hippocampus by using viral vector based approach: Modeling cognitive decline in PD

Tel B., Cakmakli G. Y., Cinar E., Mutluay S. U., Telli G., Saka E., et al.

19th International Congress of Parkinson's Disease and Movement Disorders, California, United States Of America, 14 - 18 June 2015, vol.30, (Summary Text)

2015

15. Does higher alpha synuclein aggregat density lead to more severe dopaminergic cell loss in AAV mediated over expression model of PD

YALÇIN ÇAKMAKLI G., ÇINAR E., Mutluay S. U., TELLİ G., KAZKAYASI İ., TEL B. C., et al.

Neurizon 2015, 26 - 29 May 2015, (Summary Text)

2014

16. Effect on G protein coupled estrogen receptor 1 GPER 1 on the control of pulmpnary atrerial presure

Telli G., Tel B. C., Büyükafşar K., Gümüşel B.

17th World Congress of Basic and Clinical Pharmacology, Cape-Town, South Africa, 13 - 18 July 2014, pp.68, (Summary Text)

2014

17. Hipokampüste AAV-aracılı alfa-sinüklein aşırı ifadesi ile PH modelinde kognitif değişiklikler oluşturulabilir mi?

Yalçın Çakmaklı G., Çınar E., Kazkayası İ., Telli G., Mutluay S. U., Saka Topçuoğlu E., et al.

12. Ulusal Sinirbilim Kongresi, İstanbul, Turkey, 28 - 31 May 2014, vol.77, pp.17, (Summary Text)

Funded Projects

2024 - Present

Alzheimer Hastalığının Tedavisinde Kullanılmak Üzere Gliburid Iceren Nanosüspansiyon Formülasyonlarının Geliştirilmesi ve Karakterizasyonuna Yönelik Çalışmalar

Project Supported by Higher Education Institutions , BAP Other

GÜLSÜN İNAL T. (Executive), AKDAĞ ÇAYLI Y., ŞAHİN S., TELLİ G., REÇBER T., AYTEKİN E., et al.

2023 - Present

Alzheimer Hastalığında Kullanılabilecek Yeni Bir Doğal Kaynak Prunella vulgaris L ve Etkin Bileşikleri Tübitak Proje No 121S491Ek Bütçe Desteği

Project Supported by Higher Education Institutions , BAP Other

KUTLUAY V. M. (Executive), DOĞAN Z., PEHLİVAN S., AYTEKİN E., TELLİ G.

2022 - 2025

Piperasilin tazobaktam ve karbapenem kullanımının karbapeneme dirençli gram negatif bakteriler ile fekal kolonizasyon gelişmesi üzerinde etkisinin karşılaştırılması

Project Supported by Higher Education Institutions , BAP Other

METAN G. (Executive), TELLİ G., HAZIROLAN G., AKOVA M., SARICAOĞLU T., TELLİ DİZMAN G., et al.

2023 - 2024

Voltajbağımlı potasyum kanalları alt ailesi üyesi 4 KCNE4 geninin sağlıklı ve pulmoner hipertansif dişi ve erkek sıçanların pulmoner düz kas hücrelerindeki düzeylerinin karşılaştırılması

Project Supported by Higher Education Institutions , BAP Research Project

TELLİ G. (Executive)

2023 - 2024

Dolutegravir ve Doravirinin Sirtuinler Aracılığıyla Yağ Doku Bejleşmesine Etkileri

Project Supported by Higher Education Institutions , BAP Other

İNKAYA A. Ç. (Executive), TELLİ G., UZUN M., ZEYBEK N. D., AYDIN S.

2021 - 2023

Streptozotosin ile İndüklenen Diyabet Geliştirilen Farelerde Tirotiropin Salgılattırıcı Hormonun Topikal Uygulamasının Yara İyileşmesine Etkisi

Project Supported by Higher Education Institutions , BAP Other

TELLİ G. (Executive), KAZKAYASI İ., DENİZALTI M., TİMUR S. S.

2020 - 2022

Monokrotalin İle İndüklenen Sıçan Pulmoner Hipertansiyon Modelinde Allopurinol Tedavisinin Etkisi

Project Supported by Higher Education Institutions , BAP Other

UMA M. S. (Executive), ÖNDER S. Ç., TELLİ G., KAZKAYASI İ., SOMUNCUOĞLU E. İ.

2020 - 2021

İntraserebroventriküler Streptozotosin Uygulaması ile Alzheimer Hastalığı Oluşturulmuş Farelerde İntranazal Metformin Tedavisi

TUBITAK Project , 1002 - Quick Support Program

KAZKAYASI İ. (Executive), TELLİ G.

2019 - 2020

Endemik Scutellaria Rubicunda Hornem. Subsp. Brevibracteata J.R.Edm. Bitkisinin Antienflamatuvar Etkisinin Araştırılması ve Muhtemel Etki Mekanizmasının Açıklanması

TUBITAK Project , 1002 - Quick Support Program

(Project Abstract)

Doğan Z. (Executive), Saraçoğlu İ., Telli G., Tel B. C.

2015 - 2019

Bazal gangliyonlarda ve limbik kortekste viral vektör aracılı alfa sinüklein aşırı ifadesine dayalı Parkinson hastalığı modelinde motor ve davranışsal değişikliklerin patoloji ile karşılaştırmalı olarak incelenmesi ve bu modelde rapamisin uygulamasının etkisinin araştırılması

Project Supported by Higher Education Institutions , BAP Research Project

TEL B. C. (Executive), MUTLUAY S. U., ELİBOL B., YABANOĞLU ÇİFTÇİ S., BAYSAL İ., YALÇIN ÇAKMAKLI G., et al.

2016 - 2017

Sıçan ana pulmoner arterinde intermedinin etki mekanizmasının incelenmesi

Project Supported by Higher Education Institutions , BAP Other

GÜMÜŞEL B. (Executive), TELLİ G., KANDİLCİ H. B., TEL B. C.

2015 - 2016