Effect of intermedin/adrenomedullin(2) on the pulmonary vascular bed in hypoxia-induced pulmonary hypertensive rats

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Telli G., Tel B. C., Yersal N., Korkusuz P., Gumusel B.

LIFE SCIENCES, cilt.192, ss.62-67, 2018 (SCI-Expanded, Scopus)

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 192
  • Basım Tarihi: 2018
  • Doi Numarası: 10.1016/j.lfs.2017.11.031
  • Dergi Adı: LIFE SCIENCES
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.62-67
  • Anahtar Kelimeler: Intermedin/adrenomedullin(2), Hypoxia-induced pulmonary hypertension, Isolated rat lung, Pulmonary artery, GENE-RELATED PEPTIDE, ARTERIAL-HYPERTENSION, NITRIC-OXIDE, FAMILY PEPTIDE, ADRENOMEDULLIN, VASODILATION, INTERMEDIN, MAMMALS, PATHWAY
  • Hacettepe Üniversitesi Adresli: Evet

Özet

Aims: This study aimed to investigate the effect and mechanism of action of intermedin/adrenomedullin2 (IMD/AM(2)) on the pulmonary vascular bed in pulmonary hypertensive rats.