Prof.Dr. RAHİME ŞİMŞEK

SCI, SSCI ve AHCI İndekslerine Giren Dergilerde Yayınlanan Makaleler

Synthesis and spectroscopic characterization and DFT study of benzyl 4-([1,1 '-biphenyl]-4-yl)-2,6,6-trimethyl-5-oxo-1,4,5,6,7,8-hexahydroquinoline-3-carboxylate

Yildirim S. O. , BÜYÜKMUMCU Z., Butcher R. J. , ÇETİN G. , ŞİMŞEK R.

JOURNAL OF MOLECULAR STRUCTURE, cilt.1200, 2020 (SCI İndekslerine Giren Dergi)

Synthesis of fused 1,4-dihydropyridines as potential calcium channel blockers

Ozer E. K. , GÜNDÜZ M. G. , El-Khouly A., Sara Y., ŞİMŞEK R. , İSKİT A. B. , et al.

TURKISH JOURNAL OF BIOCHEMISTRY-TURK BIYOKIMYA DERGISI, cilt.43, sa.6, ss.578-586, 2018 (SCI İndekslerine Giren Dergi)

Synthesis, structural characterization and density functional studies of ethyl 4-(biphenyl-4-yl)-2,6,6-trimethy1-5-oxo-1,4,5,6,7,8-updtte hexahydroquinoline-3-carboxylate A non-merohedral twinned structure

Yidirim S. O. , BÜYÜKMUMCU Z., Butcher R. J. , ÇETİN G. , ŞİMŞEK R. , Safak C.

JOURNAL OF MOLECULAR STRUCTURE, cilt.1163, ss.161-166, 2018 (SCI İndekslerine Giren Dergi)

Synthesis, crystal structure and antimycobacterial activities of 4-indolyl-1,4-dihydropyridine derivatives possessing various ester groups

BAYDAR E., GÜNDÜZ M. G. , KRİSHNA V. S. , ŞİMŞEK R. , SRİRAM D., Yildirim S. O. , et al.

RESEARCH ON CHEMICAL INTERMEDIATES, cilt.43, sa.12, ss.7471-7489, 2017 (SCI İndekslerine Giren Dergi)

Theoretical and experimental study of the ground and excited states of 1,4-dihydropyridine based hexahydroquinoline derivatives achieved by microwave irradiation

GÜNDÜZ M. G. , da Silva C. d. B. , ZANOTTO G. M. , TOLDO J. M. , ŞİMŞEK R. , Safak C., et al.

NEW JOURNAL OF CHEMISTRY, cilt.41, sa.20, ss.11686-11694, 2017 (SCI İndekslerine Giren Dergi)

Synthesis and photodegradation studies of analogues of muscle relaxant 1,4-dihydropyridine compounds

GÜNDÜZ M. G. , Ragno G., ŞİMŞEK R. , De Luca M., Safak C., Grande F., et al.

ACTA PHARMACEUTICA, cilt.67, sa.3, ss.341-355, 2017 (SCI İndekslerine Giren Dergi)

Free radicals properties of some gamma-irradiated organic compounds

ŞİMŞEK R. , GÜNDÜZ M. G. , Safak C., Kokpinar O., Aydin M.

BULGARIAN CHEMICAL COMMUNICATIONS, cilt.49, sa.1, ss.82-86, 2017 (SCI İndekslerine Giren Dergi)

Synthesis, structural characterization and myorelaxant activity of 4-naphthylhexahydroquinoline derivatives containing different ester groups

GÜNDÜZ M. G. , ALBAYRAK E., Isli F., Fincan G. S. O. , Yildirim S., ŞİMŞEK R. , et al.

JOURNAL OF THE SERBIAN CHEMICAL SOCIETY, cilt.81, sa.7, ss.729-738, 2016 (SCI İndekslerine Giren Dergi)

Synthesis and Biological Evaluation of New Tricyclic Dihydropyridine Based Derivatives on Potassium Channels

GÜNDÜZ M. G. , KAYA YAŞAR Y., ŞİMŞEK R. , ERDEMLİ İ. , ŞAFAK O. C.

Iranian Journal Of Pharmaceutical Research, 2016 (SCI Expanded İndekslerine Giren Dergi)

Photodegradation studies of 1,4-dihydropyridine compounds by MCR analysis on UV spectral data

Ioele G., GÜNDÜZ M. G. , DE LUCA M., ŞİMŞEK R. , Safak C., MUZZALUPO R., et al.

FUTURE MEDICINAL CHEMISTRY, cilt.8, sa.2, ss.107-115, 2016 (SCI İndekslerine Giren Dergi)

Analgesic effect of a broad-spectrum dihydropyridine inhibitor of voltage-gated calcium channels

Gadotti V. M. , Bladen C., Zhang F. X. , Chen L., GÜNDÜZ M. G. , ŞİMŞEK R. , et al.

PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY, cilt.467, sa.12, ss.2485-2493, 2015 (SCI İndekslerine Giren Dergi)

1,4-Dihydropyridine derivatives with T-type calcium channel blocking activity attenuate inflammatory and neuropathic pain

Bladen C., Gadotti V. M. , GÜNDÜZ M. G. , Berger N. D. , ŞİMŞEK R. , Safak C., et al.

PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY, cilt.467, sa.6, ss.1237-1247, 2015 (SCI İndekslerine Giren Dergi)

Microwave-assisted synthesis of condensed 1,4-dihydropyridines as potential calcium channel modulators

Ozer E. K. , GÜNDÜZ M. G. , El-Khouly A., SARA M. Y. , ŞİMŞEK R. , İSKİT A. B. , et al.

TURKISH JOURNAL OF CHEMISTRY, cilt.39, sa.4, ss.886-896, 2015 (SCI İndekslerine Giren Dergi)

Synthesis and Evaluation of 1,4-Dihydropyridine Derivatives with Calcium Channel Blocking Activity

Bladen C., GÜNDÜZ M. G. , ŞİMŞEK R. , Safak C. , Zamponi G. W.

PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY, cilt.466, sa.7, ss.1355-1363, 2014 (SCI İndekslerine Giren Dergi)

Microwave-assisted synthesis and myorelaxant activity of 9-indolyl-1,8-acridinedione derivatives

GÜNDÜZ M. G. , Isli F., El-Khouly A., Yildirim S., Fincan G. S. O. , ŞİMŞEK R. , et al.

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, cilt.75, ss.258-266, 2014 (SCI İndekslerine Giren Dergi)

ESR study of some gamma irradiated amino acids and condensed 1,4-dihydropyridines

Aydin M., ŞİMŞEK R. , GÜNDÜZ M. G. , Safak C. , Osmanoglu Y. E.

JOURNAL OF MOLECULAR STRUCTURE, cilt.1035, ss.378-382, 2013 (SCI İndekslerine Giren Dergi)

Synthesis and Myorelaxant Activity of Fused 1,4-Dihydropyridines on Isolated Rabbit Gastric Fundus

Safak C. , GÜNDÜZ M. G. , Ilhan S. O. , ŞİMŞEK R. , Isli F., Yildirim S., et al.

DRUG DEVELOPMENT RESEARCH, cilt.73, sa.6, ss.332-342, 2012 (SCI İndekslerine Giren Dergi)

Investigation of myorelaxant activity of 9-aryl-3,4,6,7-tetrahydroacridine-1,8-(2H,5H,9H,10H)-diones in isolated rabbit gastric fundus

Fincan G. S. O. , GÜNDÜZ M. G. , Vural I. M. , ŞİMŞEK R. , Sarioglu Y., Safak C.

MEDICINAL CHEMISTRY RESEARCH, cilt.21, sa.8, ss.1817-1824, 2012 (SCI İndekslerine Giren Dergi)

Synthesis of Cyclopentapyridine and Thienopyridine Derivatives as Potential Calcium Channel Modulators

GÜNDÜZ M. G. , SAFAK C. , Kaygisiz B., Kosar B. C. , ŞİMŞEK R. , Erol K., et al.

ARZNEIMITTELFORSCHUNG-DRUG RESEARCH, cilt.62, sa.4, ss.167-175, 2012 (SCI İndekslerine Giren Dergi)

Two 1,4-dihydropyridine derivatives with potential calcium-channel antagonist activity

Linden A., Safak C. , ŞİMŞEK R. , GÜNDÜZ M. G.

ACTA CRYSTALLOGRAPHICA SECTION C-STRUCTURAL CHEMISTRY, cilt.67, 2011 (SCI İndekslerine Giren Dergi)

7-Substituted Hexahydroquinoline Derivatives and their Calcium Channel Modulator Effects

GÜNDÜZ M. G. , Celebi S., Kaygisiz B., ŞİMŞEK R. , Erol K., Safak C.

LATIN AMERICAN JOURNAL OF PHARMACY, cilt.28, sa.6, ss.922-926, 2009 (SCI İndekslerine Giren Dergi)

Substituted 9-aryl-1,8-acridinedione derivatives and their effects on potassium channels

GÜNDÜZ M. G. , Dogan A. E. , ŞİMŞEK R. , Erol K., Safak C.

MEDICINAL CHEMISTRY RESEARCH, cilt.18, sa.4, ss.317-325, 2009 (SCI İndekslerine Giren Dergi)

Condensed 1,4-dihydropyridines with various esters and their calcium channel antagonist activities

Bulbul B., Ozturk G. S. , Vural M., ŞİMŞEK R. , Sarioglu Y., Linden A., et al.

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, cilt.44, sa.5, ss.2052-2058, 2009 (SCI İndekslerine Giren Dergi)

Evaluation of myorelaxant activity of 7-substituted hexahydroquinoline derivatives in isolated rabbit gastric fundus

GÜNDÜZ M. G. , Ozturk G. S. , Vural I. M. , ŞİMŞEK R. , Sarioglu Y., Safak C.

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, cilt.43, sa.3, ss.562-568, 2008 (SCI İndekslerine Giren Dergi)

Structure-activity relationships of receptor binding of 1,4-dihydropyridine derivatives

Takahashi D., Oyunzul L., Onoue S., Ito Y., Uchida S., ŞİMŞEK R. , et al.

BIOLOGICAL & PHARMACEUTICAL BULLETIN, cilt.31, sa.3, ss.473-479, 2008 (SCI İndekslerine Giren Dergi)

Synthesis of 2-Methyl-4-aryl-4,6,7,8-tetrahydro-5(1H)-quinolone Derivatives and their Effects on Potassium Channels

Oeztuerk G. S. , Vural M., Guenduez M. G. , ŞİMŞEK R. , Sarioglu Y., SAFAK C.

ARZNEIMITTELFORSCHUNG-DRUG RESEARCH, cilt.58, sa.12, ss.659-665, 2008 (SCI İndekslerine Giren Dergi)

Synthesis and calcium modulatory activity of 3-alkyloxycarbonyl-4-(disubstituted)aryl-5-oxo-1,4,5,6,7,8-hexahydroquinoline derivatives

ŞİMŞEK R. , Ozturk G. S. , Vural I. M. , GÜNDÜZ M. G. , Sarioglu Y., Safak C.

ARCHIV DER PHARMAZIE, cilt.341, sa.1, ss.55-60, 2008 (SCI İndekslerine Giren Dergi)

Studies on condensed 1,4-dihydropyridine derivatives and their calcium modulatory activities

Aydin F. , Safak C. , Simsek R. , Erol K., Ulgen M., Linden A.

PHARMAZIE, cilt.61, sa.8, ss.655-659, 2006 (SCI İndekslerine Giren Dergi)

Fused 1,4-dihydropyridines as potential calcium modulatory compounds

Safak C. , Simsek R.

MINI-REVIEWS IN MEDICINAL CHEMISTRY, cilt.6, sa.7, ss.747-755, 2006 (SCI İndekslerine Giren Dergi)

Cocrystals of diastereoisomers of 1,4-dihydropyridine derivatives

Linden A., Gunduz M. G. , SIMSEK R. , SAFAK C.

ACTA CRYSTALLOGRAPHICA SECTION C-CRYSTAL STRUCTURE COMMUNICATIONS, cilt.62, 2006 (SCI İndekslerine Giren Dergi)

4-Difluoro-substituted phenyl-5-oxo-hexahydroquinoline derivatives and their effects on calcium channels

Simsek R. , Gunduz M. G. , Sirmagul B., Safak C. , Erol K., Linden A.

ARZNEIMITTELFORSCHUNG-DRUG RESEARCH, cilt.56, sa.7, ss.529-534, 2006 (SCI İndekslerine Giren Dergi)

(+/-)-Methyl and (+/-)-ethyl 4-(2,3-difluorophenyl)-2,6,6-trimethyl-5-oxo-1,4,5,6,7,8-hexahydroquinoline-3-carboxylate

Linden A. , Simsek R. , Gunduz M. G. , Safak C.

ACTA CRYSTALLOGRAPHICA SECTION C-CRYSTAL STRUCTURE COMMUNICATIONS, cilt.61, 2005 (SCI İndekslerine Giren Dergi)

Synthesis, evaluation of the calcium antagonistic activity and biotransformation of hexahydroquinoline and furoquinoline derivatives

Simsek R. , Safak C. , Erol K., Ataman S., Ulgen M., Linden A.

ARZNEIMITTEL-FORSCHUNG-DRUG RESEARCH, cilt.53, sa.3, ss.159-166, 2003 (SCI İndekslerine Giren Dergi)

Vasorelaxing properties of some phenylacridine type potassium channel openers in isolated rabbit thoracic arteries

Berkan O. C. , Sarac B., Simsek R. , Yildirim S., Sarioglu Y., Safak C.

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, cilt.37, sa.6, ss.519-523, 2002 (SCI İndekslerine Giren Dergi)

Photochemical study of hexahydroquinoline derivatives - A new group of calcium antagonists

Mielcarek J. , Safak C., Simsek R. , Matloka A.

ARCHIV DER PHARMAZIE, cilt.335, ss.77-82, 2002 (SCI İndekslerine Giren Dergi)

Synthesis of hexahydroquinoline derivatives possessing calcium antagonistic activity

Simsek R. , Safak C. , Erol K., Sirmagul B.

PHARMAZIE, cilt.56, sa.8, ss.665-666, 2001 (SCI İndekslerine Giren Dergi)

Studies on calcium antagonist activities of 2-ethyl-3-carbmethoxy-4-aryl-5-oxo-6,6-dimethyl-1,4,5,6,7,8-hexahydroquinoline derivatives

Simsek R. , Safak C. , Erol K., Sirmagul B.

ARZNEIMITTEL-FORSCHUNG-DRUG RESEARCH, cilt.51, sa.12, ss.959-963, 2001 (SCI İndekslerine Giren Dergi)

(+/-)-9-(2-Bromophenyl)-7,7-dimethyl-1,3,4,5,6,7,8,9-octahydrofuro[3,4-b]quinoline-1,8-dione

Simsek R. , Linden A., Safak C.

ACTA CRYSTALLOGRAPHICA SECTION C-CRYSTAL STRUCTURE COMMUNICATIONS, cilt.56, ss.351-353, 2000 (SCI İndekslerine Giren Dergi)

Some azolylthioacetamides and their analgesic and antiinflammatory activities

Simsek R. , Kelicen P., Safak C. , Akgun H. , Demirdamar R.

PHARMAZIE, cilt.54, sa.3, ss.229-231, 1999 (SCI İndekslerine Giren Dergi)

Racemic ethyl 4-(2-fluorophenyl)-2,6,6-trimethyl-5-oxo-1,4,5,6,7,8-hexahydro-quinoline-3-carboxylate

Linden A. , Safak C., Simsek R.

ACTA CRYSTALLOGRAPHICA SECTION C-CRYSTAL STRUCTURE COMMUNICATIONS, cilt.54, ss.879-882, 1998 (SCI İndekslerine Giren Dergi)

Analgesic and antiinflammatory effects of some 2-mercaptobenzoxazole derivatives

Safak C. , Simsek R. , Erol K., Vural K.

PHARMAZIE, cilt.51, sa.3, ss.180-182, 1996 (SCI İndekslerine Giren Dergi)

Diğer Dergilerde Yayınlanan Makaleler

Electrochemical detection of antioxidant activities of 4-indolyl-5-oxo-6,6 (or 7,7)-dimethyl-1,4,5,6,7,8-hexahydroquinoline derivatives

SÜSLÜ İ. , ERDOĞAN KABLAN S. , Safak C. , ŞİMŞEK R.

JOURNAL OF RESEARCH IN PHARMACY, cilt.25, sa.1, ss.52-62, 2021 (ESCI İndekslerine Giren Dergi)

2,2,7,7-Tetramethyl-1,2,3,4,5,6,7,8-octahydroacridine-1,8-dione

Yildirim S. O. , Butcher R. J. , ŞİMŞEK R. , El-Khouly A., Safak C.

ACTA CRYSTALLOGRAPHICA SECTION E-CRYSTALLOGRAPHIC COMMUNICATIONS, cilt.69, 2013 (ESCI İndekslerine Giren Dergi)

Ethyl 2,7,7-trimethyl-4-(1-methyl-1H-indol-3-yl)-5-oxo-1,4,5,6,7,8-hexahydroquinoline-3-carboxylate

Yildirim S. O. , Butcher R. J. , GÜNDÜZ M. G. , El-Khouly A., ŞİMŞEK R. , Safak C.

ACTA CRYSTALLOGRAPHICA SECTION E-CRYSTALLOGRAPHIC COMMUNICATIONS, cilt.69, 2013 (ESCI İndekslerine Giren Dergi)

3,3,6,6-Tetramethyl-9-(1-methyl-1H-indol-2-yl)-1,2,3,4,5,6,7,8,9,10-deca-hydroacridine-1,8-dione

Yildirim S. O. , Butcher R. J. , El-Khouly A., Safak C. , ŞİMŞEK R.

ACTA CRYSTALLOGRAPHICA SECTION E-CRYSTALLOGRAPHIC COMMUNICATIONS, cilt.68, 2012 (ESCI İndekslerine Giren Dergi)

Ethyl 4-(5-bromo-1H-indol-3-yl)-2,6,6-trimethyl-5-oxo-1,4,5,6,7,8-hexahydroquinoline-3-carboxylate

GÜNDÜZ M. G. , Butcher R. J. , Yildirim S. O. , El-Khouly A., Safak C. , ŞİMŞEK R.

ACTA CRYSTALLOGRAPHICA SECTION E-CRYSTALLOGRAPHIC COMMUNICATIONS, cilt.68, 2012 (ESCI İndekslerine Giren Dergi)

9-(5-Bromo-1H-indol-3-yl)-1,2,3,4,5,6,7,8,9,10-decahydroacridine-1,8-dionedimethyl sulfoxide monosolvate

El-Khouly A., Yildirim S. O. , Butcher R. J. , ŞİMŞEK R. , Safak C.

ACTA CRYSTALLOGRAPHICA SECTION E-CRYSTALLOGRAPHIC COMMUNICATIONS, cilt.68, 2012 (ESCI İndekslerine Giren Dergi)

Antimicrobial Screening of 2 Methyl 3 Acyl 4 Aryl 2 6 6 and or 2 7 7 Trimethyl 1 4 5 6 7 8 Hexahydroquinoline Derivatives

GÜNDÜZ M. G. , EKİZOĞLU M. , KART D. , ŞİMŞEK R. , ŞAFAK O. C.

Hacettepe University, J. Faculty of Pharmacy, cilt.31, sa.1, ss.51-58, 2011 (Diğer Kurumların Hakemli Dergileri)

Hakemli Kongre / Sempozyum Bildiri Kitaplarında Yer Alan Yayınlar

Experimental and Molecular Modeling Investigation of Isopropyl 4-(Biphenyl-4-Yl)-2,6,6-Trimethyl-5-Oxo-1,4,5,6,7,8-Hexahydroquinoline-3-Carboxylate

Yildirim S. O. , ÇETİN G. , BÜYÜKMUMCU Z., ŞİMŞEK R. , Safak C. , Butcher R. J. , et al.

33rd International Physics Congress of the Turkish-Physical-Society (TPS), Bodrum, Türkiye, 6 - 10 Eylül 2017, cilt.1935

Antimicrobial Screening of 1 4 Dihydropyridine Derivatives

EKİZOĞLU M. , GÜNDÜZ M. G. , KART D. , ŞİMŞEK R. , ŞAFAK O. C.

4th International Meeting on Medicinal and Pharmaceutical Chemistry-6th International Symposium on Pharmaceutical Chemistry Joint Meeting, 30 Eylül - 02 Ekim 2010

Kitap & Kitap Bölümleri

Türk Farmakopesi

TUNÇBİLEK M., YEŞİLADA A., BALKAN A. , TOZKOPARAN B. , PALASKA E. , ÖZKANLI F. , et al.

T. C. Sağlık Bakanlığı Türkiye İlaç ve Tıbbi Cihaz Kurumu, Ankara, 2018

Yayınlar & Eserler

SCI, SSCI ve AHCI İndekslerine Giren Dergilerde Yayınlanan Makaleler

Diğer Dergilerde Yayınlanan Makaleler

Hakemli Kongre / Sempozyum Bildiri Kitaplarında Yer Alan Yayınlar

Kitap & Kitap Bölümleri