Prof. Dr. AYTEKİN AKYOL

Yayın Ağı

Makaleler 48

1. AKR1B1 Expression in the Colorectal Tumor Microenvironment Contributes Towards Its Prognostic Significance

DEMİRKOL CANLI S., GÜNER GEBEŞ G., Isik A., Sosic-Jurjevi B., Rom A. D., SEZA E. G., et al.

CANCER MEDICINE , cilt.14, sa.10, 2025 (SCI-Expanded, Scopus) Sürdürülebilir Kalkınma

2. **A new CRISPR-mediated Apc knockout allele leads to pyloric gland adenoma-like gastric polyps in mice with C57BL/6;FVB/N mixed background**

Uzun S., Ozcan O., Gok A., Isik A., Bakir S., ÖZCAN A., et al.

ANIMAL MODELS AND EXPERIMENTAL MEDICINE , 2025 (ESCI, Scopus)

3. **Amine Oxidase, Copper Containing 3 (Aoc3) Knockout Mice Are More Prone to DSS-induced Colitis and Colonic Tumorigenesis**

Ozcan O., AKYOL Ö., AKYOL A.

IN VIVO , cilt.38, sa.5, ss.2300-2309, 2024 (SCI-Expanded, Scopus)

4. Post-Transcriptional Regulation of Rab7a in Lysosomal Positioning and Drug Resistance in Nutrient-Limited Cancer Cells

Taskiran A. E. G., HÜSNÜGİL H. H., Soltani Z. E., Oral G., Menemenli N. S., Hampel C., et al.

TRAFFIC , cilt.25, sa.9, 2024 (SCI-Expanded, Scopus)

5. Targeting LINC00152 activates cAMP/Ca²⁺/ferroptosis axis and overcomes tamoxifen resistance in ER plus breast cancer

Saatci O., Alam R., Huynh-Dam K., Isik A., ÜNER M., BELDER N., et al.

CELL DEATH & DISEASE , cilt.15, sa.6, 2024 (SCI-Expanded, Scopus)

6. The prognostic and predictive role of class III β-Tubulin and hENT1 expression in patients with advanced pancreatic ductal adenocarcinoma

Sahin T., IŞIK A., Guven D., Ceylan F., BABAOĞLU B., AKYOL A., et al.

Pancreatology , cilt.24, sa.2, ss.279-288, 2024 (SCI-Expanded, Scopus)

7. Lysosomal alkalinization in nutrient restricted cancer cells activates cytoskeletal rearrangement to enhance partial epithelial to mesenchymal transition

HÜSNÜGİL H. H., Güleç Taşkıran A. E., GÜDERER İ., Nehri L. N., Oral G., Menemenli N. Ş., et al.

Translational Oncology , cilt.41, 2024 (SCI-Expanded, Scopus)

8. The Impact of Dose Rate on the Tumor Microenvironment Using Flattening-filter-free Beams

YILMAZ M., Gok A., Gedik M., ÇAĞLAYAN A., YEDEKÇİ F. Y., AYDIN DİLSİZ S., et al.

Clinical Oncology , 2024 (SCI-Expanded, Scopus)

9. Toxic PARP trapping upon cAMP-induced DNA damage reinstates the efficacy of endocrine therapy and CDK4/6 inhibitors in treatment-refractory ER+ breast cancer

Saatci O., Cetin M., ÜNER M., Tokat U. M., Chatzistamou I., Ersan P. G., et al.

Nature Communications , cilt.14, sa.1, 2023 (SCI-Expanded, Scopus)

10. Claudin 18.2 Expression in Gastric Adenocarcinomas in a Large Turkish Cohort

Işık A., GÜNER G., Zeyneloğlu C., DEMİRKOL CANLI S., TAŞTAN H., AKYOL A.

Abant Tıp Dergisi , cilt.12, sa.2, ss.122-130, 2023 (Hakemli Dergi)

11. Characterization of the Subcellular Distribution of Phospho-β-catenin in Colorectal Cancer

Uzun S., Isik A., KATİPOĞLU K., GÜNER G., AKYOL A.

In Vivo , cilt.37, sa.4, ss.1576-1583, 2023 (SCI-Expanded, Scopus)

12. Role of Reduced Bdnf Expression in Novel Apc Mutant Allele-induced Intestinal and Colonic Tumorigenesis in Mice

Gok A., Işik A., Bakir S., Uzun S., GÜNER G., Ozcan O., et al.

In Vivo , cilt.37, sa.4, ss.1562-1575, 2023 (SCI-Expanded, Scopus)

13. A Novel Gene List Identifies Tumors with a Stromal-Mesenchymal Phenotype and Worse Prognosis in Gastric Cancer

Demirkol Canlı S., Üner M., Kucukkaraduman B., Karaoglu D. A., Isik A., Turhan N., et al.

Cancers , cilt.15, sa.11, 2023 (SCI-Expanded, Scopus)

14. Prognostic and predictive value of tumoral DNA damage repair protein expression in patients with resected pancreatic cancer

Ceylan F., Guven D. C., Taban H., Aktepe O., ŞAHİN T. K., Kilickap S., et al.

Clinics and Research in Hepatology and Gastroenterology , cilt.47, sa.3, 2023 (SCI-Expanded, Scopus) Sürdürülebilir Kalkınma

15. Gastric Carcinoma with Lymphoid Stroma: A Combination of Mismatch Repair Deficient Medullary Type and Epstein–Barr Virus-associated Gastric Carcinomas

Üner M., Isık A., Oztop S., Karabulut E., Demirkol Canlı S., Akyol A.

International Journal of Surgical Pathology , cilt.30, sa.6, ss.623-633, 2022 (SCI-Expanded, Scopus)

16. Diffuse Large B-Cell Lymphoma, Epstein-Barr Virus -Positive Kappa Monotypic Plasma Cell Proliferation and Invasive Carcinoma, Developing in a Child With Defective Mismatch Repair

ÜNER M., Saglam A., Tukun A., Aydin B., AKYOL A., ÜNER A.

PEDIATRIC AND DEVELOPMENTAL PATHOLOGY , cilt.25, sa.3, ss.339-344, 2022 (SCI-Expanded, Scopus) Sürdürülebilir Kalkınma

17. Loss of CTNNB1 exon 3 in sclerosing angiomatoid nodular transformation of the spleen

Uzun S., Ozcan O., Isik A., Saglam A., Gedikoglu G., Demiroz A. S., et al.

VIRCHOWS ARCHIV , cilt.479, sa.4, ss.747-754, 2021 (SCI-Expanded, Scopus)

18. Intrahepatic Biliary Intraductal Papillary Mucinous Neoplasm With Intermittent Jaundice: Case Report

CENNET Ö., DOĞRUL A. B., TIRNAKSIZ M. B., ÜNER H., AKYOL A., KARÇAALTINCABA M., et al.

INTERNATIONAL SURGERY , cilt.105, sa.1-3, ss.211-214, 2021 (SCI-Expanded, Scopus)

19. Enhanced expression of HNF4 alpha during intestinal epithelial differentiation is involved in the activation of ER stress

Tunçer S., Sade-Memişoğlu A., Keşküş A., Sheraj I., Güner G., Akyol A., et al.

FEBS JOURNAL , cilt.287, sa.12, ss.2504-2523, 2020 (SCI-Expanded, Scopus)

20. A Highly Potent TACC3 Inhibitor as a Novel Anticancer Drug Candidate.

Akbulut O., Lengerli D., Saatci O., Duman E., Seker U., Isik A., et al.

Molecular cancer therapeutics , cilt.19, ss.1243-1254, 2020 (SCI-Expanded, Scopus)

21. Targeting lysyl oxidase (LOX) overcomes chemotherapy resistance in triple negative breast cancer

Saatci O., Kaymak A., Raza U., Ersan P., Akbulut O., Banister C., et al.

NATURE COMMUNICATIONS , cilt.11, sa.1, 2020 (SCI-Expanded, Scopus)

22. The potential efficacy of dietary fatty acids and fructose induced inflammation and oxidative stress on the insulin signaling and fat accumulation in mice

Tamer F., Ulug E., Akyol A., Nergiz-Unal R.

FOOD AND CHEMICAL TOXICOLOGY , cilt.135, 2020 (SCI-Expanded, Scopus)

23. Class III beta-tubulin Expression in Colorectal Neoplasms Is a Potential Predictive Biomarker for Paclitaxel Response

Oztop S., IŞIK A., GUNER G., Gurdal H., KARABULUT E., Yilmaz E., et al.

ANTICANCER RESEARCH , cilt.39, sa.2, ss.655-662, 2019 (SCI-Expanded, Scopus)

24. An immunohistochemical approach to detect oncogenic CTNNB1 mutations in primary neoplastic tissues

AKYOL A., GUNER G., OZSEKER H. S., IŞIK A., Atci O., UZUN S., et al.

LABORATORY INVESTIGATION , cilt.99, sa.1, ss.128-137, 2019 (SCI-Expanded, Scopus)

25. Morphologic and Immunohistochemical Appraisal of Primary Gastric Carcinomas

GUNER G., IŞIK A., KARABULUT E., GEDIKOGLU G., SÖKMENSÜER C., AKYOL A.

APPLIED IMMUNOHISTOCHEMISTRY & MOLECULAR MORPHOLOGY , cilt.26, sa.10, 2018 (SCI-Expanded, Scopus)

26. Undifferentiated Embryonal Sarcoma of the Liver in an Adult Patient

Beksac K., Mammadov R., Ciftci T., GÜNER G., AKYOL A., Kaynaroglu V.

CUREUS , cilt.10, sa.7, 2018 (ESCI)

27. Targeting PLK1 overcomes T-DM1 resistance via CDK1-dependent phosphorylation and inactivation of Bcl-2/xL in HER2-positive breast cancer

Saatci O., BORGONI S., Akbulut O., Durmus S., Raza U., Eyupoglu E., et al.

ONCOGENE , cilt.37, sa.17, ss.2251-2269, 2018 (SCI-Expanded, Scopus)

28. Diagnostic and Treatment Reproducibility of Cervical Intraepithelial Neoplasia / Squamous Intraepithelial Lesion and Factors Affecting the Diagnosis

SAGLAM A., USUBÜTÜN A., DOLGUN A., Mutter G. L., SALMAN M. C., KURTULAN O., et al.

TURKISH JOURNAL OF PATHOLOGY , cilt.33, sa.3, ss.177-191, 2017 (ESCI, Scopus, TRDizin)

29. Azelnidipine, a novel calcium channel blocker, ameliorates severity of colitis in DSS induced colitis in mice possibly by modulating tissue levels of TNF-alpha and IL-6

Kav T., AKYOL A., Aksoy E., Ozer C., Torgutalp M., Sivri B.

JOURNAL OF CROHNS & COLITIS , cilt.11, 2017 (SCI-Expanded, Scopus)

30. Cyanoacrylate Associated Foreign Body Granulomatous Gastritis: A Report of Three Cases

GÜNER G., KURTULAN O., KAV T., SÖKMENSÜER C., Gedikoglu G., AKYOL A.

CASE REPORTS IN PATHOLOGY , 2017 (ESCI)

31. Herediter Mide Kanserleri

Güner G., AKYOL A.

Güncel Gastroenteroloji , cilt.21, sa.1, ss.38-44, 2017 (Hakemli Dergi)

32. Evaluation of prognostic value of 2010 WHO classification of gastric neuroendocrine tumours

Kurtulan O., Turhan N., AKYOL A., Gedikoglu G., Sokmensuer C.

VIRCHOWS ARCHIV , cilt.469, 2016 (SCI-Expanded, Scopus)

33. The prognostic significance of Cerb-B2 expression in gastric carcinomas

Babaoglu B., AKYOL A., Sokmensuer C., Gedikoglu G.

VIRCHOWS ARCHIV , cilt.469, 2016 (SCI-Expanded, Scopus)

34. Kolorektal Kanserdeki Biyobelirteçler

AKYOL A.

Güncel Gastroenteroloji , cilt.20, sa.2, ss.120-129, 2016 (Hakemli Dergi)

35. Image of the Month: A Neuroendocrine Tumor Invading All Portal Venous System Components.

Ozturk O., Bayraktar Y., Akyol A.

The American journal of gastroenterology , cilt.111, ss.311, 2016 (SCI-Expanded, Scopus)

36. Tissue-Specific Effects of Reduced β-catenin Expression on Adenomatous Polyposis Coli Mutation-Instigated Tumorigenesis in Mouse Colon and Ovarian Epithelium.

Feng Y., Sakamoto N., Wu R., Liu J., Wiese A., Green M., et al.

PLoS genetics , cilt.11, 2015 (SCI-Expanded, Scopus)

37. Morphological analysis of the relationship between the duodenal biopsy samples diagnosed as "increased intraepithelial lymphocytes" with Helicobacter pylori gastritis and Celiac Disease

Babaoglu B., Ozturk O., AKYOL A., Koklu S., Sokmensuer C.

VIRCHOWS ARCHIV , cilt.467, 2015 (SCI-Expanded, Scopus)

38. Histopathological Evaluation of Orchiectomy Specimens in 51 Late Postpubertal Men with Unilateral Cryptorchidism

Koni A., Ozseker H. S., Arpali E., Kilinc E., DOĞAN H. S., AKYOL A., et al.

JOURNAL OF UROLOGY , cilt.192, sa.4, ss.1183-1188, 2014 (SCI-Expanded, Scopus)

39. Intraductal Papillary Mucinous Neoplasms of the Pancreas (IPMNs): 11 cases of Hacettepe experience

Bugdayci M., AKYOL A., SÖKMENSÜER C., Gedikoglu G.

VIRCHOWS ARCHIV , cilt.465, 2014 (SCI-Expanded, Scopus)

40. Maternal Cdx2 is dispensable for mouse development

Blij S., Frum T., Akyol A., Fearon E., Ralston A.

DEVELOPMENT , cilt.139, sa.21, ss.3969-3972, 2012 (SCI-Expanded, Scopus)

41. Reproducibility of endometrial intraepithelial neoplasia diagnosis is good, but influenced by the diagnostic style of pathologists

USUBÜTÜN A., Mutter G. L., Saglam A., Dolgun A., Ozkan E. A., Ince T., et al.

MODERN PATHOLOGY , cilt.25, sa.6, ss.877-884, 2012 (SCI-Expanded, Scopus)

42. CDX2 Regulates Multidrug Resistance 1 Gene Expression in Malignant Intestinal Epithelium

Takakura Y., Hinoi T., Oue N., Sasada T., Kawaguchi Y., Okajima M., et al.

CANCER RESEARCH , cilt.70, sa.17, ss.6767-6778, 2010 (SCI-Expanded, Scopus)

43. Generating somatic mosaicism with a Cre recombinase - microsatellite sequence transgene

Akyol A., Hinoi T., Feng Y., Bommer G. T., Glaser T. M., Fearon E. R.

NATURE METHODS , cilt.5, sa.3, ss.231-233, 2008 (SCI-Expanded, Scopus)

44. Mouse model of colonic adenoma-carcinoma progression based on somatic Apc inactivation

Hinoi T., Akyol A., Theisen B. K., Ferguson D. O., Greenson J. K., Williams B. O., et al.

CANCER RESEARCH , cilt.67, sa.20, ss.9721-9730, 2007 (SCI-Expanded, Scopus) Sürdürülebilir Kalkınma

45. Mouse model of human ovarian endometrioid adenocarcinoma based on somatic defects in the Wnt/beta-catenin and PI3K/Pten signaling pathways

Wu R., Hendrix-Lucas N., Kuick R., Zhai Y., Schwartz D. R., Akyol A., et al.

CANCER CELL , cilt.11, sa.4, ss.321-333, 2007 (SCI-Expanded, Scopus)

46. Drosophila split ends homologue SHARP functions as a positive regulator of wnt/beta-catenin/T-cell factor signaling in neoplastic transformation

Feng Y., Bommer G. T., Zhai Y., Akyol A., Hinoi T., Winer I., et al.

CANCER RESEARCH , cilt.67, sa.2, ss.482-491, 2007 (SCI-Expanded, Scopus) Sürdürülebilir Kalkınma

47. CDX2-regulated expression of iron transport protein hephaestin in intestinal and colonic epithelium

HINOI T., GESINA G., Akyol A., KUICK R., HANASH S., GIORDANO T., et al.

GASTROENTEROLOGY , cilt.128, sa.4, ss.946-961, 2005 (SCI-Expanded, Scopus)

48. Myasthenia gravis and lymphoblastic lymphoma involving the thymus: A rare association

Uner A., Abali H., Engin H., Akyol A., Ruacan E., Tan E., et al.

LEUKEMIA & LYMPHOMA , cilt.42, sa.3, ss.527-531, 2001 (SCI-Expanded, Scopus)

Hakemli Bilimsel Toplantılarda Yayımlanmış Bildiriler 11

1. Overcoming chemotherapy resistance in triple negative breast cancer via targeting lysyl oxidase (LOX)

Saatçi Ö., Akbulut Ö., Rezaeain A., Banister C., Sikirzhytski V., AKSOY S., et al.

AACR Virtual Special Conference, Virtual, Amerika Birleşik Devletleri, 11 - 12 Ocak 2021, cilt.81, (Özet Bildiri)

2. Heterocyclic amine intake along with high fat diet may trigger predisposition to atherosclerosis

Yuruk A., GÜMÜŞ D., AKYOL A., KIZIL M., NERGİZ ÜNAL R.

88th EAS Congress, 04 Ekim 2020, (Özet Bildiri)

3. Class III Beta-Tubulin Expression in Colrectal Cancer Development

öztop s., IŞIK A., taş g. g., YILMAZ E., AKYOL A.

IONCC 2017, 21 - 23 Eylül 2017, (Özet Bildiri)

4. Class III Beta-Tubulin Expression in Colorectal Cancer Development

Öztop S., Işık A., Güner Taş G., YILMAZ E., AKYOL A.

1. ULUSLARARASI KANSER VE İYON KANALLARI KONGRESİ, Türkiye, 21 - 23 Eylül 2017, ss.53, (Özet Bildiri)

5. Azelnidipine, a novel calcium channel blocker, ameliorates severity of colitis in DSS induced colitis in mice possibly by modulating tissue levels of TNF-alpha and IL-6

KAV T., AKYOL A., KAHRAMANOĞLU AKSOY E., ÖZER C., TORGUTALP M., SİVRİ B.

12th Congress of ECCO, Barselona, İspanya, 15 Şubat 2017 - 18 Şubat 2018, cilt.11, ss.93-94, (Özet Bildiri)

9. DNA hatalı eşleşme tamir mekanizması bozukluğu içeren kolorektal kanserlerin dörtlü immünohistokimyasal panel ile değerlendirilmesi

AKYOL A., Üner M., Işık A., Öztop S., GEDİKOĞLU M. G., SÖKMENSÜER C.

25. Ulusal Patoloji Kongresi, Türkiye, 14 - 17 Ekim 2015, (Özet Bildiri)

10. İleri evre medüller tip mide karsinomlarının klinikopatolojik ve moleküler özellikleri

Üner M., Güner G., Işık A., Karabulut E., GEDİKOĞLU M. G., SÖKMENSÜER C., et al.

25. Ulusal Patoloji Kongresi, Türkiye, 14 - 17 Ekim 2015, (Özet Bildiri)

11. Morphological analysis of the relationship between the duodenal biopsy samples diagnosed as increased intraepithelial lymphocytes with Helicobacter pylori gastritis and Celiac Disease

Babaoğlu B., Ozturk Ö., AKYOL A., KÖKLÜ S., SÖKMENSÜER C.

27th European Congress of Pathology, 5 - 09 Ekim 2015, cilt.467, ss.130, (Özet Bildiri)

Kitaplar 1

1. Mide kanseri ve prekürsör lezyonlar: Güncel ve moleküler sınıflama.

GÜNER TAŞ G., AKYOL A., GÜNER G.

Gastrointestinal Patolojide Yenilikler., Özdamar ŞO, Editör, Türkiye Klinikleri, Ankara, ss.22-28, 2019

Metrikler

Yayın

Yayın (WoS)

Yayın (Scopus)

Atıf (WoS)

704

H-İndeks (WoS)

Atıf (Scopus)

818

H-İndeks (Scopus)

Atıf (Scholar)

H-İndeks (Scholar)

Proje

Tez Danışmanlığı

Açık Erişim

BM Sürdürülebilir Kalkınma Amaçları

Yayınlar & Eserler