Low indoleamine 2,3-dioxygenase activity in persistent food allergy in children

BUYUKTIRYAKI B., ŞAHİNER Ü. M., GİRGİN G., BİRBEN E., SOYER O. U., CAVKAYTAR O., ...Daha Fazla

ALLERGY, cilt.71, sa.2, ss.258-266, 2016 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 71 Sayı: 2
  • Basım Tarihi: 2016
  • Doi Numarası: 10.1111/all.12785
  • Dergi Adı: ALLERGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.258-266
  • Anahtar Kelimeler: cell culture, children, food allergy, indoleamine 2, 3-dioxygenase (IDO), tolerance, SUPPRESS TRYPTOPHAN BREAKDOWN, DENDRITIC CELLS, INTERFERON-GAMMA, SERUM TRYPTOPHAN, TOXOPLASMA-GONDII, HUMAN-FIBROBLASTS, INDUCTION, EXPRESSION, TOLERANCE, ACID
  • Hacettepe Üniversitesi Adresli: Evet

Özet

BackgroundIndoleamine 2,3-dioxygenase (IDO), which degrades tryptophan (Trp) to kynurenine (Kyn), has been demonstrated to contribute to modulation of allergic responses. However, the role of IDO in food allergy has not yet been elucidated.