Alteration of the microRNA expression profile in familial Mediterranean fever patients

Akkaya-Ulum Y. Z., Balci-Peynircioglu B., KARADAĞ Ö., Eroglu F. K., KALYONCU U., KİRAZ S., ...More

CLINICAL AND EXPERIMENTAL RHEUMATOLOGY, vol.35, no.6, 2017 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 35 Issue: 6
  • Publication Date: 2017
  • Journal Name: CLINICAL AND EXPERIMENTAL RHEUMATOLOGY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Keywords: inflammation, epigenetics, microRNAs, familial Mediterranean fever, array, inflammatory pathways, INFLAMMATION
  • Hacettepe University Affiliated: Yes

Abstract

Objective. Phenotypic heterogeneity in familial Mediterranean fever (FMF) disease indicated that FMF is not a simple monogenic disease. Therefore it has been suggested that epigenetic factors can be one of the reason for the variations. We undertook this study to test potential involvement of miRNAs in the pathogenesis of FMF.