Ultrastructural changes in the circumventricular organs after experimental subarachnoid hemorrhage

Akpinar G., Acikog B., Surucu S., Celik H., Cagavi F.

NEUROLOGICAL RESEARCH, vol.27, no.6, pp.580-585, 2005 (Peer-Reviewed Journal) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 27 Issue: 6
  • Publication Date: 2005
  • Doi Number: 10.1179/016164105x48752
  • Journal Indexes: Science Citation Index Expanded, Scopus
  • Page Numbers: pp.580-585


Objectives: Circumventricular organs (CVOs) are fine, periventricular, neurotransmitter-rich structures that are devoid of a blood-brain barrier and are known for their secretory role controlling fluid and electrolyte balance, thirst and even reproduction. Common pathologies of the brain such as trauma or bleeding affect CVOs, and hence their function. However, at what stage of these disease processes are CVOs affected and the time sequence of their recovery is still not clear. The aim of this study was to detect the morphological changes in CVOs using electron microscopy after experimental subarachnoid hemorrhage (SAH).