Obesity is associated with increased myocardial oxidative stress

VINCENT, ALİ; POWERS, SK; STEWART, DJ; SHANELY, RA; Demirel, H; NAITO, H

doi:10.1038/sj.ijo.0800761

Obesity is associated with increased myocardial oxidative stress

VINCENT H., POWERS S., STEWART D., SHANELY R., Demirel H., NAITO H.

INTERNATIONAL JOURNAL OF OBESITY, cilt.23, sa.1, ss.67-74, 1999 (SCI-Expanded, Scopus)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 23 Sayı: 1
Basım Tarihi: 1999
Doi Numarası: 10.1038/sj.ijo.0800761
Dergi Adı: INTERNATIONAL JOURNAL OF OBESITY
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.67-74
Anahtar Kelimeler: obesity, myocardium, lipid peroxidation, antioxidant enzymes, reactive oxygen species (ROS), ZUCKER-FATTY RAT, FREE-RADICALS, CELLULAR DEFENSES, SKELETAL-MUSCLE, ISCHEMIA, EXERCISE, PROTEINS, HEART, ASSAY
Hacettepe Üniversitesi Adresli: Evet

Özet

OBJECTIVE: To determine: 1) whether obesity predisposes the myocardium to oxidative stress as evidenced by higher tissue levels of myocardial lipid peroxidation, and 2) what cellular mechanisms are responsible for this predisposition.