Obesity is associated with increased myocardial oxidative stress

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VINCENT H., POWERS S., STEWART D., SHANELY R., Demirel H., NAITO H.

INTERNATIONAL JOURNAL OF OBESITY, cilt.23, sa.1, ss.67-74, 1999 (SCI-Expanded)

• Yayın Türü: Makale / Tam Makale
• Cilt numarası: 23 Sayı: 1
• Basım Tarihi: 1999
• Doi Numarası: 10.1038/sj.ijo.0800761
• Dergi Adı: INTERNATIONAL JOURNAL OF OBESITY
• Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
• Sayfa Sayıları: ss.67-74
• Anahtar Kelimeler: obesity, myocardium, lipid peroxidation, antioxidant enzymes, reactive oxygen species (ROS), ZUCKER-FATTY RAT, FREE-RADICALS, CELLULAR DEFENSES, SKELETAL-MUSCLE, ISCHEMIA, EXERCISE, PROTEINS, HEART, ASSAY
• Hacettepe Üniversitesi Adresli: Evet

Özet

OBJECTIVE: To determine: 1) whether obesity predisposes the myocardium to oxidative stress as evidenced by higher tissue levels of myocardial lipid peroxidation, and 2) what cellular mechanisms are responsible for this predisposition.