Association of serum total bilirubin level with severity of coronary atherosclerosis is linked to systemic inflammation

Akboga, Mehmet; Canpolat, UĞUR; Sahinarslan, Asif; Alsancak, Yakup; Nurkoc, Serdar; Aras, Dursun; Aydogdu, Sinan; Abaci, Adnan

doi:10.1016/j.atherosclerosis.2015.02.051

Association of serum total bilirubin level with severity of coronary atherosclerosis is linked to systemic inflammation

Akboga M. K., Canpolat U., Sahinarslan A., Alsancak Y., Nurkoc S., Aras D., ...More

ATHEROSCLEROSIS, vol.240, no.1, pp.110-114, 2015 (SCI-Expanded, Scopus)

Publication Type: Article / Article
Volume: 240 Issue: 1
Publication Date: 2015
Doi Number: 10.1016/j.atherosclerosis.2015.02.051
Journal Name: ATHEROSCLEROSIS
Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Page Numbers: pp.110-114
Keywords: Bilirubin, Inflammation, CRP, NLR, RDW, Atherosclerosis, LOW-DENSITY-LIPOPROTEIN, CELL DISTRIBUTION WIDTH, C-REACTIVE PROTEIN, LYMPHOCYTE RATIO, ENDOTHELIAL FUNCTION, INVERSE RELATIONSHIP, ARTERY-DISEASE, NEUTROPHIL, METAANALYSIS, RISK
Hacettepe University Affiliated: Yes

Abstract

Objective: Although cardiovascular protective action of bilirubin has been attributed to its antioxidant effect, there was scarce data regarding the anti-inflammatory properties. Herein, we aimed to assess the relationship between serum total bilirubin level and severity of coronary artery disease (CAD) in association with the direct inflammatory marker such as C-reactive protein (CRP), the other indirect markers included in inflammation process such as neutrophil to lymphocyte ratio (NLR) and red cell distribution width (RDW) in patients with stable CAD.