MICROFLUIDIC DEVICE FOR SYNTHESIS OF CHITOSAN NANOPARTICLES


ÇETİN B., Taze S., AŞIK M. D., TUNCEL S. A.

ASME Fluids Engineering Division Summer Meeting, Nevada, Amerika Birleşik Devletleri, 7 - 11 Temmuz 2013 identifier

  • Yayın Türü: Bildiri / Tam Metin Bildiri
  • Cilt numarası:
  • Basıldığı Şehir: Nevada
  • Basıldığı Ülke: Amerika Birleşik Devletleri
  • Hacettepe Üniversitesi Adresli: Hayır

Özet

Chitosan nanoparticles have a biodegradable, biocompatible, non-toxic structure, and commonly used for drug delivery systems. In this paper, simulation of a microfluidic device for the synthesis of chitosan nanoparticle is presented. The flow filed together with the concentration field within the microchannel network is simulated using COMSOL Multiphysics (R) simulation environment. Different microchannel geometries are analyzed, and the mixing performance of these configurations are compared. As a result, a 3D design for a microfluidics platform which includes four channel each of which performs the synthesis in parallel is proposed. Future research directions regarding the fabrication of the microfluidic device and experimentation phase are addressed and discussed.