Three novel mutations in the apolipoprotein E gene in a sample of individuals with type 2 diabetes mellitus

Stephens, JW; SÖZEN, MUSTAFA; Whittall, RA; Caslake, MJ; Bedford, D; Acharya, J; Hurel, SJ; Humphries, SE

doi:10.1373/j.clinchem.2004.040121

Three novel mutations in the apolipoprotein E gene in a sample of individuals with type 2 diabetes mellitus

Stephens J., SÖZEN M. M., Whittall R., Caslake M., Bedford D., Acharya J., ...More

CLINICAL CHEMISTRY, vol.51, no.1, pp.119-124, 2005 (SCI-Expanded, Scopus)

Publication Type: Article / Article
Volume: 51 Issue: 1
Publication Date: 2005
Doi Number: 10.1373/j.clinchem.2004.040121
Journal Name: CLINICAL CHEMISTRY
Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Page Numbers: pp.119-124
Hacettepe University Affiliated: No

Abstract

Background: Apolipoprotein E (apoE) is found in association with triglyceride-rich lipoproteins and is the ligand for the removal of these particles from the plasma. Genetic variations in exon 4 lead to three common gene variants: E2, E3, and E4.