Coenzyme Q10 concentrations and antioxidant status in tissues of breast cancer patients

Portakal O., Ozkaya Ö., Inal M., Bozan B., Kosan M., Sayek I.

CLINICAL BIOCHEMISTRY, vol.33, no.4, pp.279-284, 2000 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 33 Issue: 4
  • Publication Date: 2000
  • Doi Number: 10.1016/s0009-9120(00)00067-9
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.279-284
  • Hacettepe University Affiliated: Yes


Objectives: An increasing amount of experimental and epidemiological evidence implicates the involvement of oxygen derived radicals in the pathogenesis of cancer development. Oxygen derived radicals are able to cause damage to membranes, mitochondria, and macromolecules including proteins, lipids and DNA. Accumulation of DNA damages has been suggested to contribute to carcinogenesis. It would, therefore, be advantageous to pinpoint the effects of oxygen derived radicals in cancer development.