Coenzyme Q10 concentrations and antioxidant status in tissues of breast cancer patients

Portakal O., Ozkaya Ö., Inal M., Bozan B., Kosan M., Sayek I.

CLINICAL BIOCHEMISTRY, cilt.33, sa.4, ss.279-284, 2000 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 33 Sayı: 4
  • Basım Tarihi: 2000
  • Doi Numarası: 10.1016/s0009-9120(00)00067-9
  • Dergi Adı: CLINICAL BIOCHEMISTRY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.279-284
  • Hacettepe Üniversitesi Adresli: Evet

Özet

Objectives: An increasing amount of experimental and epidemiological evidence implicates the involvement of oxygen derived radicals in the pathogenesis of cancer development. Oxygen derived radicals are able to cause damage to membranes, mitochondria, and macromolecules including proteins, lipids and DNA. Accumulation of DNA damages has been suggested to contribute to carcinogenesis. It would, therefore, be advantageous to pinpoint the effects of oxygen derived radicals in cancer development.