Coenzyme Q10 concentrations and antioxidant status in tissues of breast cancer patients

Portakal, O; Ozkaya, ÖZAY; Inal, ME; Bozan, B; Kosan, M; Sayek, I

doi:10.1016/s0009-9120(00)00067-9

Coenzyme Q10 concentrations and antioxidant status in tissues of breast cancer patients

Copy For Citation

Portakal O., Ozkaya Ö., Inal M., Bozan B., Kosan M., Sayek I.

CLINICAL BIOCHEMISTRY, vol.33, no.4, pp.279-284, 2000 (SCI-Expanded)

Publication Type: Article / Article
Volume: 33 Issue: 4
Publication Date: 2000
Doi Number: 10.1016/s0009-9120(00)00067-9
Journal Name: CLINICAL BIOCHEMISTRY
Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Page Numbers: pp.279-284
Hacettepe University Affiliated: Yes

Abstract

Objectives: An increasing amount of experimental and epidemiological evidence implicates the involvement of oxygen derived radicals in the pathogenesis of cancer development. Oxygen derived radicals are able to cause damage to membranes, mitochondria, and macromolecules including proteins, lipids and DNA. Accumulation of DNA damages has been suggested to contribute to carcinogenesis. It would, therefore, be advantageous to pinpoint the effects of oxygen derived radicals in cancer development.