Effect of intraarticular injection of lornoxicam on the articular cartilage & synovium in rat

Saricaoglu F., Dal D., ATİLLA P., Iskit A. B., Tarhan O., Asan E., ...Daha Fazla

INDIAN JOURNAL OF MEDICAL RESEARCH, cilt.127, sa.4, ss.362-365, 2008 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 127 Sayı: 4
  • Basım Tarihi: 2008
  • Dergi Adı: INDIAN JOURNAL OF MEDICAL RESEARCH
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.362-365
  • Anahtar Kelimeler: intraarticular injection, lornoxicam, nonsteroidal anti-inflammatory drugs (NSAIDs), postoperative analgesia, rat, POSTOPERATIVE ANALGESIA, PAIN RELIEF, EFFICACY, NSAIDS
  • Hacettepe Üniversitesi Adresli: Evet

Özet

Background & objectives: Intraarticular (i.a) drug application is consider to be a new therapeutic approach for the treatment of postoperative pain after arthroscopic knee surgery without any systemic adverse effects. Lornoxicam, a nonsteroid anti-inflammatory drug is a short acting agent, and its anti-inflammatory and analgesic activity may be effective in the postoperative pain management in minor surgery. In this study, the effects of intraarticular administration of lornoxicam on the synovium and articular cartilage in the rat knee joint were investigated.