Anaphylactic Reaction Owing to Ondansetron Administration in a Child With Neuroblastoma and Safe Use of Granisetron: A Case Report

Demir H. A., BATU AKAL E. D., YALÇIN B., CİVELEK E., SAÇKESEN C., Buyukpamkcu M.

JOURNAL OF PEDIATRIC HEMATOLOGY ONCOLOGY, cilt.32, sa.8, 2010 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 32 Sayı: 8
  • Basım Tarihi: 2010
  • Doi Numarası: 10.1097/mph.0b013e3181ea214a
  • Dergi Adı: JOURNAL OF PEDIATRIC HEMATOLOGY ONCOLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Anahtar Kelimeler: anaphylactic reaction, anaphlaxis, children, ondansetron, chemotherapy, antiemetics
  • Hacettepe Üniversitesi Adresli: Evet

Özet

A 1-year-old girl with stage-IV neuroblastoma developed ondansetron hydrochloride anaphylaxis. Safe use of granisetron as an antiemetic after skin prick, oral, and intravenous challenge tests is presented. We present this case to emphasize that ondansetron hydrochloride may cause a serious anaphylactic reaction. In such a case, granisetron may be given to patients as an antiemetic after some provocative tests performed.