Anaphylactic Reaction Owing to Ondansetron Administration in a Child With Neuroblastoma and Safe Use of Granisetron: A Case Report


Demir H. A., BATU AKAL E. D., YALÇIN B., CİVELEK E., SAÇKESEN C., Buyukpamkcu M.

JOURNAL OF PEDIATRIC HEMATOLOGY ONCOLOGY, vol.32, no.8, 2010 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 32 Issue: 8
  • Publication Date: 2010
  • Doi Number: 10.1097/mph.0b013e3181ea214a
  • Journal Name: JOURNAL OF PEDIATRIC HEMATOLOGY ONCOLOGY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Keywords: anaphylactic reaction, anaphlaxis, children, ondansetron, chemotherapy, antiemetics
  • Hacettepe University Affiliated: Yes

Abstract

A 1-year-old girl with stage-IV neuroblastoma developed ondansetron hydrochloride anaphylaxis. Safe use of granisetron as an antiemetic after skin prick, oral, and intravenous challenge tests is presented. We present this case to emphasize that ondansetron hydrochloride may cause a serious anaphylactic reaction. In such a case, granisetron may be given to patients as an antiemetic after some provocative tests performed.