Evaluation of the Effect of Minoxidil in Experimental Cerebral Vasospasm

Tekiner A., Sargon M. F., Bayar M. A., Caydere M., Yucel D., Senes M., ...Daha Fazla

Neurotrauma and Vascular Neurosurgery Joint EANS Annual Meeting / 4th World ICH Conference, Newcastle, Avustralya, 2 - 05 Mayıs 2011, ss.87-91 identifier

  • Yayın Türü: Bildiri / Tam Metin Bildiri
  • Cilt numarası:
  • Basıldığı Şehir: Newcastle
  • Basıldığı Ülke: Avustralya
  • Sayfa Sayıları: ss.87-91
  • Hacettepe Üniversitesi Adresli: Evet

Özet

Minoxidil (6-piperidin-1-ylpyrimidine-2,4-diamine 3-oxide) is a potassium channel opener and causes hyperpolarization of cell membranes. By this way it causes vasodilatation. In this experimental study, subrachnoid haemorrhage (SAH) model was performed to the rabbits basilar artery and cerebral cortex were examined by histological and oxidative/nitrosative stress parameters.