Evaluation of the Effect of Minoxidil in Experimental Cerebral Vasospasm

Tekiner A., Sargon M. F., Bayar M. A., Caydere M., Yucel D., Senes M., ...More

Neurotrauma and Vascular Neurosurgery Joint EANS Annual Meeting / 4th World ICH Conference, Newcastle, Australia, 2 - 05 May 2011, pp.87-91 identifier

  • Publication Type: Conference Paper / Full Text
  • Volume:
  • City: Newcastle
  • Country: Australia
  • Page Numbers: pp.87-91
  • Hacettepe University Affiliated: Yes

Abstract

Minoxidil (6-piperidin-1-ylpyrimidine-2,4-diamine 3-oxide) is a potassium channel opener and causes hyperpolarization of cell membranes. By this way it causes vasodilatation. In this experimental study, subrachnoid haemorrhage (SAH) model was performed to the rabbits basilar artery and cerebral cortex were examined by histological and oxidative/nitrosative stress parameters.