SYNTHESIS AND PHARMACOLOGY OF SOME NEW CARBAMODITHIOIC ACID-ESTERS
ARZNEIMITTELFORSCHUNG-DRUG RESEARCH, sa.2, ss.123-126, 1992 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Basım Tarihi: 1992
- Dergi Adı: ARZNEIMITTELFORSCHUNG-DRUG RESEARCH
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, International Pharmaceutical Abstracts
- Sayfa Sayıları: ss.123-126
- Hacettepe Üniversitesi Adresli: Hayır
Özet
In this study 13 new dithiocarbamates were prepared by reacting 3-methyl-6-chloroacetyl-benzoxazolinone with potassium N,N-disubstituted dithiocarbamate derivatives. The structures of the compounds were confirmed by UV, IR, H-1-NMR, mass spectroscopic methods and elementary analysis. The anticholinergic activity was tested on rabbit ileum. With exception of one compound all derivatives exhibited a stronger antihistaminic activity as compared with their anticholinergic action.