The effects of mitochondrial transplantation in acetaminophen-induced liver toxicity in rats


Ulger O., Kubat G. B., Cicek Z., Celik E., ATALAY Ö., Suvay S., ...Daha Fazla

LIFE SCIENCES, cilt.279, 2021 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 279
  • Basım Tarihi: 2021
  • Doi Numarası: 10.1016/j.lfs.2021.119669
  • Dergi Adı: LIFE SCIENCES
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, BIOSIS, CAB Abstracts, Chimica, EMBASE, MEDLINE, Veterinary Science Database
  • Hacettepe Üniversitesi Adresli: Evet

Özet

Aims: Acetaminophen (APAP) toxicity is one of the leading causes of acute liver injury-related death and liver failure worldwide. In many studies, mitochondrial dysfunction has been identified as an important cause of damage in APAP toxicity. Therefore, our study aimed to investigate the possible effects of mitochondrial transplantation on liver damage due to APAP toxicity.