Duration of intensive care unit stay as a guide for the timely treatment of Carbapenem-resistant Enterobacterales bloodstream infection: a case-control study

Karadoǧan, Eda; Uzar, Hanife; Özden, Asll; Dalglç, Büşra; Demir, Mervenur; Sertçelik, Ahmet; Telli Dizman, Gülçin; Çaklr, BANU; Hazlrolan, Gülşen; Uzun, Omrum; Metan, Gökhan

doi:10.1017/ash.2025.10198

Duration of intensive care unit stay as a guide for the timely treatment of Carbapenem-resistant Enterobacterales bloodstream infection: a case-control study

Karadoǧan E., Uzar H., Özden A., Dalglç B., Demir M., Sertçelik A., ...Daha Fazla

Antimicrobial Stewardship and Healthcare Epidemiology, cilt.5, sa.1, 2025 (ESCI, Scopus)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 5 Sayı: 1
Basım Tarihi: 2025
Doi Numarası: 10.1017/ash.2025.10198
Dergi Adı: Antimicrobial Stewardship and Healthcare Epidemiology
Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), Scopus
Açık Arşiv Koleksiyonu: AVESİS Açık Erişim Koleksiyonu
Hacettepe Üniversitesi Adresli: Evet

Özet

Timely selection of appropriate empirical treatment for carbapenem-resistant Enterobacterales (CRE) bacteremia remains challenging, especially when prior antibiotic exposure data is unavailable. We found that intensive care unit stay duration predicts CRE bacteremia - with ≥8 days showing 81% sensitivity and 96% PPV - providing a practical clue for empirical therapy decisions.