Regular Treatment With Aspirin 300 mg/day After Desensitization in Patients With N-ERD: 12-Year Results

KAYA S. B., Cakmak M. E., DAMADOĞLU E., KARAKAYA G., KALYONCU A. F.

TURKISH THORACIC JOURNAL, vol.22, no.5, pp.376-380, 2021 (ESCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 22 Issue: 5
  • Publication Date: 2021
  • Doi Number: 10.5152/turkthoracj.2021.0298
  • Journal Name: TURKISH THORACIC JOURNAL
  • Journal Indexes: Emerging Sources Citation Index (ESCI), Scopus, TR DİZİN (ULAKBİM)
  • Page Numbers: pp.376-380
  • Keywords: Aspirin desensitization, asthma, endoscopic sinus surgery, nasal polyp, NSAID hypersensitivity, LONG-TERM TREATMENT, OUTCOMES
  • Hacettepe University Affiliated: Yes

Abstract

OBJECTIVE: Aspirin desensitization is recommended for patients with nonsteroidal anti-inflammatory drug (NSAID) hypersensitivity, in whom asthma is uncontrolled despite medical treatment, and/or frequent endoscopic sinus surgery (ESS) is required due to nasal polyps. There are few studies in the literature on long-term follow-up of patients undergoing regular aspirin treatment after desensitization. This study aims to evaluate the effect of regular aspirin treatment on respiratory function, symptom control, quality of life, and the number of nasal surgeries required during a period of 12 years.