Drug-Associated Thrombocytopenia as a Rare and Devastating Side Effect of Octreotide in a Cirrhotic Patients: A Case Report and Current Literature Review

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ALTINTOP S. E., GÜVEN A. T., KESKİN O.

HASEKI TIP BULTENI-MEDICAL BULLETIN OF HASEKI, vol.59, no.3, pp.265-267, 2021 (ESCI) identifier identifier identifier

  • Publication Type: Article / Review
  • Volume: 59 Issue: 3
  • Publication Date: 2021
  • Doi Number: 10.4274/haseki.galenos.2021.6775
  • Journal Name: HASEKI TIP BULTENI-MEDICAL BULLETIN OF HASEKI
  • Journal Indexes: Emerging Sources Citation Index (ESCI), Scopus, Academic Search Premier, CINAHL, EMBASE, Directory of Open Access Journals, TR DİZİN (ULAKBİM)
  • Page Numbers: pp.265-267
  • Hacettepe University Affiliated: Yes

Abstract

Variceal bleeding is one of the most serious outcomes encountered in portal hypertension. It represents one of the leading causes of death in cirrhotic patients. Octreotide infusion is the mainstay of treatment in variceal bleeding. It shows its effects by lowering portal venous pressure. Here, we present a patient with variceal bleeding who experienced sudden thrombocytopenia after octreotide infusion. Cessation of the octreotide therapy has resulted in a quick recovery of the platelet counts. Naranjo adverse drug reaction probability scale has revealed a probable relationship with 6 points. The case is reported in discussion with the existing 4 cases in the literature.