Different molecular mechanisms for the eight types of human lung cancers

Criss W.

INDOOR AND BUILT ENVIRONMENT, cilt.14, sa.6, ss.537-541, 2005 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 14 Sayı: 6
  • Basım Tarihi: 2005
  • Doi Numarası: 10.1177/1420326x04059282
  • Dergi Adı: INDOOR AND BUILT ENVIRONMENT
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.537-541
  • Hacettepe Üniversitesi Adresli: Hayır

Özet

The various types of lung cancer each have unique properties and their cells show specific changes in molecular regulatory control mechanisms. Each type has mutations/amplifications/over expression of several oncogenes, mutations or loss of cancer suppressor genes, increased telomerase activity and loss of chromosome 3p. These molecular genotypic changes are discussed with regard to the unique phenotypic characteristics of human lung cancers.