Central precocious puberty in a girl with Williams syndrome: the result of treatment with GnRH analogue

Utine G., Alikasifoglu A., Alikasifoglu M., Tuncbilek E.

EUROPEAN JOURNAL OF MEDICAL GENETICS, cilt.49, sa.1, ss.79-82, 2006 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 49 Sayı: 1
  • Basım Tarihi: 2006
  • Doi Numarası: 10.1016/j.ejmg.2005.04.020
  • Dergi Adı: EUROPEAN JOURNAL OF MEDICAL GENETICS
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.79-82
  • Hacettepe Üniversitesi Adresli: Evet

Özet

Williams syndrome (WS) is a well-known microdeletion syndrome characterized by specific facial features, retardation in growth and development, typical personality and cardiac defects. Poor growth potential is further affected by central precocious puberty (CPP) which is frequent in these patients. A WS patient with CPP is presented, whose pubertal development and bone age progression were arrested by administration of GnRH analogues. The case is reported to discuss the role of GnRH analogues for management of CPP in patients with WS. (c) 2005 Elsevier SAS. All rights reserved.