Epidemiology and management of healthcare-associated bloodstream infections in non-neutropenic immunosuppressed patients: a review of the literature


ÇALIK BAŞARAN N., AŞÇIOĞLU HAYRAN S.

THERAPEUTIC ADVANCES IN INFECTIOUS DISEASE, cilt.4, sa.6, ss.171-191, 2017 (ESCI) identifier

  • Yayın Türü: Makale / Derleme
  • Cilt numarası: 4 Sayı: 6
  • Basım Tarihi: 2017
  • Doi Numarası: 10.1177/2049936117733394
  • Dergi Adı: THERAPEUTIC ADVANCES IN INFECTIOUS DISEASE
  • Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), EMBASE, Directory of Open Access Journals
  • Sayfa Sayıları: ss.171-191
  • Hacettepe Üniversitesi Adresli: Evet

Özet

Advancements in medicine have led to a considerable increase in the proportion of patients living with severe chronic diseases, malignancies, and HIV infections. Most of these conditions are associated with acquired immune-deficient states and treatment-related immunosuppression. Although infections as a result of neutropenia have long been recognized and strategies for management were developed, non-neutropenic immunosuppression has been overlooked. Recently, community-acquired infections in patients with frequent, significant exposure to healthcare settings and procedures have been classified as healthcare-associated infections' since they are more similar to hospital-acquired infections. Most of the non-neutropenic immunosuppressed patients have frequent contact with the healthcare system due to their chronic and severe diseases. In this review, we focus on the healthcare-associated bloodstream infections in the most common non-neutropenic immunosuppressive states and provide an update of the recent evidence for the management of these infections.