The clay samples taken from studied area Nigde-Dikilitas located place in the northeast part of Nigde province in the Central Anatolian region have been investigated by means of FTIR spectroscopy. Firstly, the FTIR spectra of beidellite, illite, illite-smectite mixed layer, kaolinite, chlorite (ripidolite), nontronite, montmorillonite, Ca-montmorillonite, Na-montmorillonite known as standard natural clays and then anhydrite, gypsum, quartz+feldspar, illite+quartz+feldspar clays to be found in clays with the standard clays have been also taken, respectively. The minerals have been determined by comparing the spectrum of every sample with the spectra of the standard clays and combined clays. It has been observed that the existence of the O-H, Al-Al-OH, Al-Mg-OH, and Si-O-Si groups in the FTIR spectrum measurements of the samples belonging to the lower, middle and upper levels of Dikilitas clay profiles (D1), (D2, D3), and (D4), respectively. In addition, it has been found that these samples including quartz, amorphous silica, feldspar, and Na-montmorillonite and these silicate samples have a T-O-T (tetrahedral-octahedral-tetrahedral) smectite structure.