Clinical and electrophysiological findings in mesial temporal lobe epilepsy with hippocampal sclerosis, based on the recent histopathological classifications

TEZER, HATİCE; XASIYEV, FADİME; SOYLEMEZOGLU, Figen; BİLGİNER, BURÇAK; Oguz, Kader; SAYGI, SERAP

doi:10.1016/j.eplepsyres.2016.08.012

Clinical and electrophysiological findings in mesial temporal lobe epilepsy with hippocampal sclerosis, based on the recent histopathological classifications

TEZER F. I., XASIYEV F. İ., SOYLEMEZOGLU F., BİLGİNER B., Oguz K. K., SAYGI S.

EPILEPSY RESEARCH, vol.127, pp.50-54, 2016 (SCI-Expanded, Scopus)

Publication Type: Article / Article
Volume: 127
Publication Date: 2016
Doi Number: 10.1016/j.eplepsyres.2016.08.012
Journal Name: EPILEPSY RESEARCH
Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Page Numbers: pp.50-54
Keywords: Epilepsy, Seizure, Hippocampal sclerosis, Temporal lobe epilepsy, Pathology, Types of hippocampal sclerosis, INTERNATIONAL CONSENSUS CLASSIFICATION, RETROSPECTIVE ANALYSIS, DIAGNOSTIC METHODS, TASK-FORCE, SURGERY, COMMISSION, PREDICTORS, MORTALITY, LOBECTOMY
Hacettepe University Affiliated: Yes

Abstract

Background: Hippocampal sclerosis (HS) is a common pathology in MTLE, patients may show different surgical outcomes and clinical features. The 2013 ILAE classification subdivides HS into 3 types (HS type 1: severe neuronal loss and gliosis predominantly in CAl and CA4 regions; - HS type 2: CAl predominant; HS type 3: CA4 predominant) and includes "gliosis only, as no-HS". The association of clinical and electrophysiological findings with different HS types has not been reported previously in detail.