Clinical and electrophysiological findings in mesial temporal lobe epilepsy with hippocampal sclerosis, based on the recent histopathological classifications

TEZER F. I., XASIYEV F. İ., SOYLEMEZOGLU F., BİLGİNER B., Oguz K. K., SAYGI S.

EPILEPSY RESEARCH, vol.127, pp.50-54, 2016 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 127
  • Publication Date: 2016
  • Doi Number: 10.1016/j.eplepsyres.2016.08.012
  • Journal Name: EPILEPSY RESEARCH
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.50-54
  • Keywords: Epilepsy, Seizure, Hippocampal sclerosis, Temporal lobe epilepsy, Pathology, Types of hippocampal sclerosis, INTERNATIONAL CONSENSUS CLASSIFICATION, RETROSPECTIVE ANALYSIS, DIAGNOSTIC METHODS, TASK-FORCE, SURGERY, COMMISSION, PREDICTORS, MORTALITY, LOBECTOMY
  • Hacettepe University Affiliated: Yes

Abstract

Background: Hippocampal sclerosis (HS) is a common pathology in MTLE, patients may show different surgical outcomes and clinical features. The 2013 ILAE classification subdivides HS into 3 types (HS type 1: severe neuronal loss and gliosis predominantly in CAl and CA4 regions; - HS type 2: CAl predominant; HS type 3: CA4 predominant) and includes "gliosis only, as no-HS". The association of clinical and electrophysiological findings with different HS types has not been reported previously in detail.