Analysis of TNF-alpha (-308) polymorphism and gingival crevicular fluid TNF-alpha levels in aggressive and chronic periodontitis: A preliminary report

Yucel O. O., Berker E., MESCI L., ERATALAY K., TEPE E., TEZCAN I.

CYTOKINE, vol.72, no.2, pp.173-177, 2015 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 72 Issue: 2
  • Publication Date: 2015
  • Doi Number: 10.1016/j.cyto.2015.01.001
  • Journal Name: CYTOKINE
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.173-177
  • Hacettepe University Affiliated: Yes


Objectives: The purpose of this study was to determine the differences in the distribution of TNF-alpha (-308) gene polymorphism among aggressive periodontitis, chronic periodontitis and periodontally healthy individuals and also to investigate whether this polymorphism is associated with gingival crevicular fluid TNF-alpha levels and periodontal disease severity.