DALI: Defining Antibiotic Levels in Intensive Care Unit Patients: Are Current beta-Lactam Antibiotic Doses Sufficient for Critically Ill Patients?

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Roberts J. A., Paul S. K., AKOVA M., Bassetti M., De Waele J. J., Dimopoulos G., ...Daha Fazla

CLINICAL INFECTIOUS DISEASES, cilt.58, sa.8, ss.1072-1083, 2014 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 58 Sayı: 8
  • Basım Tarihi: 2014
  • Doi Numarası: 10.1093/cid/ciu027
  • Dergi Adı: CLINICAL INFECTIOUS DISEASES
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.1072-1083
  • Hacettepe Üniversitesi Adresli: Evet

Özet

Background. Morbidity and mortality for critically ill patients with infections remains a global healthcare problem. We aimed to determine whether beta-lactam antibiotic dosing in critically ill patients achieves concentrations associated with maximal activity and whether antibiotic concentrations affect patient outcome.