White blood cell count and ratio changes in newborns after granulocyte colony-stimulating factor treatments

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BÜYÜKEREN M., YİĞİT Ş., ÇELİK H. T., YURDAKÖK M.

PAEDIATRICA INDONESIANA, cilt.61, sa.5, ss.240-246, 2021 (ESCI) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 61 Sayı: 5
  • Basım Tarihi: 2021
  • Doi Numarası: 10.14238/pi61.5.2021.240-6
  • Dergi Adı: PAEDIATRICA INDONESIANA
  • Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), Scopus, CINAHL, Directory of Open Access Journals
  • Sayfa Sayıları: ss.240-246
  • Anahtar Kelimeler: newborn, granulocyte colony-stimulating factor, neutropenia, immature/total ratio, PRETERM NEWBORNS, NEUTROPENIA, SEPSIS, TRIAL
  • Hacettepe Üniversitesi Adresli: Evet

Özet

Background Granulocyte-colony stimulating factor (G-CSF) is frequently used to treat neonatal neutropenia. There is a paucity of data in the literature on when immature to total neutrophil ratio (I/T ratio) can be accurately used as a sepsis marker after G-CSF therapy, as well as when I/T ratio returns to normal values expected in newborns who did not receive G-CSF.