Acantholimon koycegizicum Dogan & Akaydin sp. nova and A. goksunicum Dogan & Akaydin sp. nova (Plumbaginaceae) are described and illustrated from Anatolia, Turkey. Acantholimon koycegizicum grows on serpentine mountain slopes between Koycegiz and Kaplicalar (C2 Mugla) in South West Anatolia, and A. goksunicum grows on calcareous mountain steppe in Goksun (B6 Kahramanmaras) in SE Anatolia. The species are closely related to A. calvertii, an endemic confined to East Anatolia. Diagnostic morphological characters are discussed. A revised key to Turkish Acantholimon species with 2-5-branched terminal spikes and previous years' stem with persistent circinate leaf bases, is also presented along with notes on the ecology, biogeography and conservational status of the new species.