Enantioselective addition of diethylzinc to aldehydes catalyzed by beta-amino alcohols derived from (1R,2S)-norephedrine
APPLIED ORGANOMETALLIC CHEMISTRY, cilt.24, sa.1, ss.33-37, 2010 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 24 Sayı: 1
- Basım Tarihi: 2010
- Doi Numarası: 10.1002/aoc.1583
- Dergi Adı: APPLIED ORGANOMETALLIC CHEMISTRY
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Sayfa Sayıları: ss.33-37
- Hacettepe Üniversitesi Adresli: Evet
Özet
beta-Amino alcohols derived from (1R,2S)-norephedrine were synthesized and used as ligands in the catalytic enantioselective diethylzinc addition to benzaldehydes. N-alkylated (1R,2S)-norephedrine-based derivative 3a gave the highest enantioselectivity. The effects of different parameters on the enantioselectivity of the product were investigated. Copyright (C) 2009 John Wiley & Sons, Ltd.