Protective role of erdosteine pretreatment on oleic acid-induced acute lung injury

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Erdem A., Gedikli E., Yersal N., Karaismailoğlu S., Muftuoglu S. F., Fadillioglu E., ...More

JOURNAL OF SURGICAL RESEARCH, vol.213, pp.234-242, 2017 (SCI-Expanded, Scopus)

  • Publication Type: Article / Article
  • Volume: 213
  • Publication Date: 2017
  • Doi Number: 10.1016/j.jss.2017.02.061
  • Journal Name: JOURNAL OF SURGICAL RESEARCH
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.234-242
  • Keywords: Erdosteine, Oleic acid, Acute lung injury, RESPIRATORY-DISTRESS-SYNDROME, SUPEROXIDE-DISMUTASE, LIPOIC ACID, RATS, ERYTHROCYTE, TOXICITY, THERAPY, ASSAY
  • Open Archive Collection: AVESIS Open Access Collection
  • Hacettepe University Affiliated: Yes

Abstract

Background: Erdosteine is a mucolytic agent with antioxidant and anti-inflammatory effects. We evaluated the protective effect of erdosteine pretreatment on oleic acid (OA)induced acute lung injury.