Protective role of erdosteine pretreatment on oleic acid-induced acute lung injury

Erdem, AYŞEN; Gedikli, ESRA; Yersal, NİLGÜN; Karaismailoğlu, SERKAN; Muftuoglu, SEVDA; Fadillioglu, ERSİN; Tuncer, MELTEM

doi:10.1016/j.jss.2017.02.061

Protective role of erdosteine pretreatment on oleic acid-induced acute lung injury

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Erdem A., Gedikli E., Yersal N., Karaismailoğlu S., Muftuoglu S. F., Fadillioglu E., ...More

JOURNAL OF SURGICAL RESEARCH, vol.213, pp.234-242, 2017 (SCI-Expanded)

Publication Type: Article / Article
Volume: 213
Publication Date: 2017
Doi Number: 10.1016/j.jss.2017.02.061
Journal Name: JOURNAL OF SURGICAL RESEARCH
Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Page Numbers: pp.234-242
Keywords: Erdosteine, Oleic acid, Acute lung injury, RESPIRATORY-DISTRESS-SYNDROME, SUPEROXIDE-DISMUTASE, LIPOIC ACID, RATS, ERYTHROCYTE, TOXICITY, THERAPY, ASSAY
Hacettepe University Affiliated: Yes

Abstract

Background: Erdosteine is a mucolytic agent with antioxidant and anti-inflammatory effects. We evaluated the protective effect of erdosteine pretreatment on oleic acid (OA)induced acute lung injury.