Facile synthesis of heteroaryl substituted gamma-lactams from nitrovinyl arenes
TURKISH JOURNAL OF CHEMISTRY, cilt.42, sa.1, ss.29-35, 2018 (SCI-Expanded, Scopus, TRDizin)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 42 Sayı: 1
- Basım Tarihi: 2018
- Doi Numarası: 10.3906/kim-1705-25
- Dergi Adı: TURKISH JOURNAL OF CHEMISTRY
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
- Sayfa Sayıları: ss.29-35
- Hacettepe Üniversitesi Adresli: Evet
Özet
Aliphatic nitroalkanes with different functional groups were synthesized from the Michael addition reactions of active methylene compounds 2 and nitrovinyl arenes 1 in high yields. The synthesized Michael adducts were subjected to intramolecular cyclization to give heteroaryl substituted gamma-lactams in good to high yields under mild reaction conditions.