Basal cell carcinoma (BCC) is the most common skin cancer. The gold standard therapy is surgery in the treatment of BCC. The recomended surgical method is Mohs micrographic surgery, as it provides the highest cure rates in high-risk BCC in terms of recurrence. It is well known that certain drugs such as aspirin, warfarin and clopidogrel cause bleeding complications during dermatologic surgery. In contrast, it is not well known to have bleeding side effects similar to these drugs. Herein, we present ibrutinib-associated hematoma and ecchymosis in a patient with BCC who underwent Mohs micrographic surgery.