Ionizing radiation and its effects on pharmaceuticals

SARCAN E. T., ÖZER A. Y.

JOURNAL OF RADIOANALYTICAL AND NUCLEAR CHEMISTRY, cilt.323, sa.1, ss.1-11, 2020 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 323 Sayı: 1
  • Basım Tarihi: 2020
  • Doi Numarası: 10.1007/s10967-019-06954-3
  • Dergi Adı: JOURNAL OF RADIOANALYTICAL AND NUCLEAR CHEMISTRY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, Aerospace Database, Analytical Abstracts, Biotechnology Research Abstracts, CAB Abstracts, Chimica, Communication Abstracts, EMBASE, Food Science & Technology Abstracts, INSPEC, Metadex, Pollution Abstracts, Public Affairs Index, Veterinary Science Database, Civil Engineering Abstracts
  • Sayfa Sayıları: ss.1-11
  • Anahtar Kelimeler: X-ray, Electron-beam, Gamma-ray, Microwave, Radiolysis, E-BEAM IRRADIATION, X-RAY, GAMMA-RADIATION, AQUEOUS-SOLUTIONS, RADIOLOGICAL SAFETY, STERILIZATION, DRUGS, RADIOSTERILIZATION, RADIOSTABILITY, DEGRADATION
  • Hacettepe Üniversitesi Adresli: Evet

Özet

Radiation is used for different purposes such as sterilization, imaging, analysis and security. Sterilization, one of the the using area of radiation, is important issue for industries. The disadvantages of heat and chemical sterilization on medicines, medical devices and foodstuffs have made important the use of radiation sterilization. Officinal sterilization method are available (25 kGy gamma-rays) in the pharmacopeias. Other ionizing radiations are getting popular because of their advantages and changing conditions on gamma-sterilization. In this article, the results of different types of ionizing radiation exposure in different doses and several analytical methods used to detect differences have been evaluated.