Prospective Randomized Study on the Effects of Improved Sleep Quality After Craniotomy on Melatonin Concentrations and Inflammatory Response in Neurosurgical Intensive Care Patients

Arik, Emine; Dolgun, Habibullah; Hanalioglu, ŞAHİN; Sahin, Omer; Ucar, Fatma; Yazicioglu, Dilek; Dogan, Ihsan; Yilmaz, Erdal

doi:10.1016/j.wneu.2020.05.017

Prospective Randomized Study on the Effects of Improved Sleep Quality After Craniotomy on Melatonin Concentrations and Inflammatory Response in Neurosurgical Intensive Care Patients

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Arik E., Dolgun H., Hanalioglu Ş., Sahin O. S., Ucar F., Yazicioglu D., ...More

WORLD NEUROSURGERY, vol.140, 2020 (SCI-Expanded)

Publication Type: Article / Article
Volume: 140
Publication Date: 2020
Doi Number: 10.1016/j.wneu.2020.05.017
Journal Name: WORLD NEUROSURGERY
Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, CAB Abstracts, EMBASE, Index Islamicus, MEDLINE, Veterinary Science Database
Keywords: Cranial surgery, Intensive care, Interleukin, Melatonin, ICU
Hacettepe University Affiliated: Yes

Abstract

OBJECTIVE: Sleep disorders in intensive care units after a craniotomy can decrease melatonin secretion and increase the inflammatory stress response. The aim of this study was to investigate the influence of improving sleep quality via eye patches and earplugs on melatonin secretion and inflammatory mediator release.