Prospective Randomized Study on the Effects of Improved Sleep Quality After Craniotomy on Melatonin Concentrations and Inflammatory Response in Neurosurgical Intensive Care Patients

Arik E., Dolgun H., Hanalioglu Ş., Sahin O. S., Ucar F., Yazicioglu D., ...More

WORLD NEUROSURGERY, vol.140, 2020 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 140
  • Publication Date: 2020
  • Doi Number: 10.1016/j.wneu.2020.05.017
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, CAB Abstracts, EMBASE, Index Islamicus, MEDLINE, Veterinary Science Database
  • Keywords: Cranial surgery, Intensive care, Interleukin, Melatonin, ICU
  • Hacettepe University Affiliated: Yes


OBJECTIVE: Sleep disorders in intensive care units after a craniotomy can decrease melatonin secretion and increase the inflammatory stress response. The aim of this study was to investigate the influence of improving sleep quality via eye patches and earplugs on melatonin secretion and inflammatory mediator release.