Comparison of early versus late onset familial Mediterranean fever

Yasar Bilge N. S., Sari I., Solmaz D., Senel S., Emmungil H., KILIÇ L., ...More

INTERNATIONAL JOURNAL OF RHEUMATIC DISEASES, vol.21, no.4, pp.880-884, 2018 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 21 Issue: 4
  • Publication Date: 2018
  • Doi Number: 10.1111/1756-185x.13259
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.880-884
  • Keywords: age at onset of disease, early onset, familial Mediterranean fever, M694V, TURKISH PATIENTS, TURKEY, MULTICENTER, AMYLOIDOSIS, FMF
  • Hacettepe University Affiliated: Yes


AimFamilial Mediterranean fever (FMF) is the most common autoinflammatory disease. One of the common characteristics of this disease is its young age predominance. Nearly 90% of patients experience disease flares during early adult age periods. Currently there are limited data for the comparison of early versus late onset FMF and therefore the primary aim of this study was to investigate these two subsets with regard to their certain demographic, clinical and genetic differences.