Assessment of ST2 and Reg3a levels in patients with acute graft-versus-host disease after allogeneic hematopoietic stem cell transplantation

ALADAĞ KARAKULAK E., DEMİROĞLU H., Malkan Ü. Y., Akman U., GÖKER H., BÜYÜKAŞIK Y.

TURKISH JOURNAL OF MEDICAL SCIENCES, vol.51, no.1, pp.355-358, 2021 (SCI-Expanded) identifier identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 51 Issue: 1
  • Publication Date: 2021
  • Doi Number: 10.3906/sag-2007-17
  • Journal Name: TURKISH JOURNAL OF MEDICAL SCIENCES
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, CAB Abstracts, EMBASE, MEDLINE, Veterinary Science Database, TR DİZİN (ULAKBİM)
  • Page Numbers: pp.355-358
  • Keywords: Suppression of tumorigenicity 2, regenerating isletderived 3-alpha, graft-versus-host disease, allogeneic hematopoietic stem cell transplantation, MORTALITY
  • Hacettepe University Affiliated: Yes

Abstract

Background/aim: Graft-versus-host disease (GVHD) is a crucial complication leading to significant morbidity and mortality allogeneic hematopoietic stem cell transplantation which occurs in approximately half of the transplant recipients. Suppression of tumorigenicity 2 (ST2) and regenerating islet-derived 3-alpha(Reg3a) might be important biomarkers to predict acute GVHD.