The term "nutraceutical" was coined from "nutrition" and "pharmaceutics" in 1989 by Stephen DeFelice, MD. Nutraceuticals as an extract or food has preventive and physiological effects in chronic diseases. According to Merriam-Webster, nutraceutical is defined as a food compound that provides medical or health benefits besides its nutritious effect. There is confusion in terminology between the terms of food supplements, nutraceuticals and food additives and the term food supplement is often used instead of nutraceuticals in practice. The term nutraceuticals includes a concentrate, a metabolite, a constituent, an extract, or combinations of these ingredients as a powder or liquid. The products are found in various pharmaceutical dosage forms such as pill, gel, capsule, tablet but not accepted as a drug. In US, the dietary ingredients such as a vitamin, a mineral, an herb or other botanicals, an amino acid, an enzyme, some tissues and secretory glands are also accepted in this group when taken orally. In this study, nutraceuticals which are used due to different regulations in many countries are discussed and some examples having antioxidant, estrogenic activities and as a diet are given.