Real-world data on MTX tolerance with regimens used in children versus adults

KAYA AKCA Ü., Farisogullari B., YARDIMCI G. K., SAĞ E., ATALAY E., KASAP CÜCEOĞLU M., ...Daha Fazla

CLINICAL RHEUMATOLOGY, cilt.40, sa.12, ss.5095-5102, 2021 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 40 Sayı: 12
  • Basım Tarihi: 2021
  • Doi Numarası: 10.1007/s10067-021-05802-8
  • Dergi Adı: CLINICAL RHEUMATOLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, CAB Abstracts, EMBASE, MEDLINE, Veterinary Science Database
  • Sayfa Sayıları: ss.5095-5102
  • Anahtar Kelimeler: Methotrexate, Intolerance, Methotrexate intolerance severity score, JUVENILE IDIOPATHIC ARTHRITIS, METHOTREXATE INTOLERANCE, RHEUMATOID-ARTHRITIS, PARENTERAL METHOTREXATE, FOLINIC ACID, RISK-FACTORS, TOXICITY, SUPPLEMENTATION, PREVALENCE, THERAPY
  • Hacettepe Üniversitesi Adresli: Evet

Özet

Objective Methotrexate (MTX) is one of the most commonly used disease-modifying anti-rheumatic drugs which can cause gastrointestinal side effects. MTX intolerance is defined as gastrointestinal and behavioral symptoms occurring before and after MTX administration. This study aims to evaluate and compare the frequency of methotrexate intolerance in adult and pediatric patients.